DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17612 and CG2120

DIOPT Version :9

Sequence 1:	NP_608824.1	Gene:	CG17612 / 33639	FlyBaseID:	FBgn0031597	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster

Alignment Length:	361	Identity:	87/361 - (24%)
Similarity:	142/361 - (39%)	Gaps:	64/361 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 LEEPAIGSCRVCLEQSDNLTNIFDDAHQYGIPIATILSQYTGMPVEKGDSFSEYICVTCLDVVKN 243
            |.:..:|:..||||.......:.|           :..:...|.:|..:..|||   ..|::|..
  Fly    15 LADDDLGNYDVCLEDLQLFAQLED-----------LSGERLPMEMELLNPGSEY---DLLELVNG 65

  Fly   244 AFDDLESKENTIQMYRQPKEEIIDIDSIPVKNKPVDYEVTGKPPHRCPQCPKIFLLAAKLQAHIR 308
            |.....:.|:......:||.       .|...:   :..||| .|.|..|.:.|..|..|:.|..
  Fly    66 ALQQRNTTEHKPTDMCKPKR-------TPTTKR---HRTTGK-DHTCDICDRRFSEAYNLRIHKM 119

  Fly   309 THNETRTTEPPRLKCPMCPSIYMKRGCLEAHMWIHRASDERESELEPPYRCPHCPKLFLYSSFLE 373
            ||    |.|.|.: |..|...:.:...|..|...|.|        |.|::|..|.|.|.|:::|.
  Fly   120 TH----TDEKPHV-CVECGKGFRQLNKLRIHAVTHTA--------ERPHKCDICGKGFRYANYLT 171

  Fly   374 IHIQTHEDVSQRLSRKSSHKC--AQCADVFSDVSSLKDHVKIHAGERTFKCPLCLMSFQEESNLK 436
            :|.:.|       :.:..:.|  ..|...|..:.:.:.|.|:....:|...|...::.||:
  Fly   172 VHRRLH-------TGEKPYPCLATDCHLSFHSIHARRIHTKLRHAAQTDPDPEHPLAEQEQ---- 225

  Fly   437 SHDCAHTRFKCHKCSKFFESQNYLDFHFKKSHTTKGPFKC--IKCQQTFQKRNGLKEHISSQVCV 499
             .|.:...|.|..||:....|.||..|.|: |..:..|.|  .:|.:.|...:.||.|   |:
  Fly   226 -RDTSALSFTCPVCSRVLTDQCYLSIHLKR-HYNQRDFPCPQPECGKRFFSASELKHH---QI-- 283

  Fly   500 QFLRSKSPGQIFPCPKCPKKFSIEDNYQMHHATHKK 535
                :.:..:.|.||.||.:|..:.|::.|...|::
  Fly   284 ----AHTQQRPFACPLCPARFLRKSNHKQHLKVHER 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17612	NP_608824.1	zf-AD	187..>246	CDD:285071	13/58 (22%)
		C2H2 Zn finger	290..310	CDD:275368	6/19 (32%)
		C2H2 Zn finger	323..343	CDD:275370	4/19 (21%)
		zf-C2H2_8	356..438	CDD:292531	18/83 (22%)
		C2H2 Zn finger	359..379	CDD:275368	7/19 (37%)
		C2H2 Zn finger	394..414	CDD:275368	5/21 (24%)
		C2H2 Zn finger	422..438	CDD:275368	3/15 (20%)
		C2H2 Zn finger	447..463	CDD:275368	6/15 (40%)
		C2H2 Zn finger	476..505	CDD:275368	7/30 (23%)
		C2H2 Zn finger	513..533	CDD:275368	7/19 (37%)
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	568..584	CDD:275368
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	6/19 (32%)
		zf-H2C2_2	113..138	CDD:290200	9/29 (31%)
		C2H2 Zn finger	129..149	CDD:275368	4/19 (21%)
		zf-H2C2_2	142..166	CDD:290200	10/31 (32%)
		COG5048	151..>264	CDD:227381	32/133 (24%)
		C2H2 Zn finger	157..177	CDD:275368	7/19 (37%)
		C2H2 Zn finger	185..206	CDD:275368	4/20 (20%)
		C2H2 Zn finger	235..255	CDD:275368	8/20 (40%)
		C2H2 Zn finger	263..285	CDD:275368	7/30 (23%)
		C2H2 Zn finger	293..313	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446559
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930