DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17612 and che-1

DIOPT Version :9

Sequence 1:	NP_608824.1	Gene:	CG17612 / 33639	FlyBaseID:	FBgn0031597	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_001076598.1	Gene:	che-1 / 183847	WormBaseID:	WBGene00000483	Length:	273	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	66/301 - (21%)
Similarity:	102/301 - (33%)	Gaps:	103/301 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 PAIGSCRVCLEQSDNLTNIFDDAHQYGIPIATILSQYTGMPVEKGDSFSEYICVTCLDV------ 240
            |:.|:.:..|:|::|......:...:|        .|.|......:|.|.:.....|::
Worm    43 PSSGTTQQALQQTENGIIQGQNGSDHG--------AYGGWRQHDWNSTSSWSIGNQLEMENGTLT 99

  Fly   241 ----------VKNAFDDLESKENTIQMYRQ-----------------PKEEIIDIDSIPVKNKPV 278
                      ::|....:.|...|...:||                 ||:|.:.:.....::.|
Worm   100 MSHGATNDGNIRNNQQMMTSNHITTDSFRQIPPSGLCYMDPTPSLRLPKKEPLPVQRPMARSTP- 163

  Fly   279 DYEVTGKPPHRCPQCPKIFLLAAKLQAHIRTHNETRTTEPPRLKCPMCPSIYMKRGCLEAHMWIH 343
                   .|.||..|.|.|..||.|.||.|.|..
Worm   164 -------KPFRCQTCGKAFSQAANLTAHKRIHTG------------------------------- 190

  Fly   344 RASDERESELEPPYRCPHCPKLFLYSSFLEIHIQTHEDVSQRLSRKSSHKCAQCADVFSDVSSLK 408
                      |.|:.||.|.:.|..||.|..|.:||       :.:..:.||||...|:|.|:|.
Worm   191 ----------EKPFMCPVCNRPFSQSSSLVTHRRTH-------TGERPYPCAQCEKAFTDSSTLT 238

  Fly   409 DHVKIHAGERTFKCPLCLMSFQEESNLKSHDCAHTRFKCHK 449
            .|::.|.|.:.:.|.:|:|.|.:..||      |...|.||
Worm   239 KHLRTHTGHKPYVCSICMMKFTQSGNL------HRHMKTHK 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17612	NP_608824.1	zf-AD	187..>246	CDD:285071	10/74 (14%)
		C2H2 Zn finger	290..310	CDD:275368	10/19 (53%)
		C2H2 Zn finger	323..343	CDD:275370	0/19 (0%)
		zf-C2H2_8	356..438	CDD:292531	28/81 (35%)
		C2H2 Zn finger	359..379	CDD:275368	8/19 (42%)
		C2H2 Zn finger	394..414	CDD:275368	9/19 (47%)
		C2H2 Zn finger	422..438	CDD:275368	6/15 (40%)
		C2H2 Zn finger	447..463	CDD:275368	2/3 (67%)
		C2H2 Zn finger	476..505	CDD:275368
		C2H2 Zn finger	513..533	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	568..584	CDD:275368
che-1	NP_001076598.1	zf-C2H2	166..188	CDD:278523	11/21 (52%)
		C2H2 Zn finger	168..188	CDD:275368	10/19 (53%)
		zf-H2C2_2	180..205	CDD:290200	11/65 (17%)
		C2H2 Zn finger	196..216	CDD:275368	8/19 (42%)
		zf-H2C2_2	208..232	CDD:290200	8/30 (27%)
		C2H2 Zn finger	224..244	CDD:275368	9/19 (47%)
		zf-H2C2_2	237..261	CDD:290200	8/23 (35%)
		C2H2 Zn finger	252..272	CDD:275368	8/25 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000