DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17612 and C09F5.3

DIOPT Version :9

Sequence 1:	NP_608824.1	Gene:	CG17612 / 33639	FlyBaseID:	FBgn0031597	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_001367485.1	Gene:	C09F5.3 / 182454	WormBaseID:	WBGene00015649	Length:	378	Species:	Caenorhabditis elegans

Alignment Length:	375	Identity:	80/375 - (21%)
Similarity:	129/375 - (34%)	Gaps:	91/375 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 PVKNKPVDYEVTGKPPHRCPQCPKIFLLAAKLQAH------------IRTHNETRTTEPPRLKCP 324
            |..:|.:..|...|    |..|..:....::||:|            |.|.|...:|:  |:.|.
Worm    30 PASSKSIKQENLLK----CELCSTVCSSISQLQSHTLSEHVPEKKPSISTSNSAPSTK--RVACQ 88

  Fly   325 MCPSIYMKRGCLEAHMWIHRASDERESELEPPYRCPHCPKLFLYSSFLEIHIQTHEDVSQRLS-R 388
            .|...:........||..|.:|  ..|:|   :.||.||   :.:.|.:...|.....:|.|. :
Worm    89 QCEDTFEDFAQFAIHMKSHLSS--VTSQL---FFCPICP---VGTPFRDKKSQLEHLTTQHLQIQ 145

  Fly   389 KSSHKCAQCADVFSDVSSLKDHVKIHAGE--RTFKCPLCLMSFQEESNLKSHDCAHTR----FKC 447
            .:.|.|:.|...|....:    ..:|..|  :.:.|..|....:.|...|.|...|:|    :.|
Worm   146 VTQHICSICDSAFPSPQA----QSVHFAEAHKKYSCTNCDFETENEKTFKEHSKQHSRQLIMYGC 206

  Fly   448 HKCSKFFESQNYLDFHFKKSH-------------TTKGP--------FKCIKCQQTFQKRNGLKE 491
            ..|:..:.||.:|..|.:.||             |...|        .:|..|.::....:||.|
Worm   207 ALCATSYPSQLHLITHVQMSHDQETFYPPSLPIPTPPSPKSTPKQRVLQCSVCDESVLGEDGLDE 271

  Fly   492 HISSQVC-VQFLRSKSPGQIFPCPKCPKKFSIEDNYQMHHATHKKVKTVIERHNCTQCKKSYQNK 555
            |...:.| |:|...        |..|.:....|.::..|...|.|    ...|:|..|::|.::.
Worm   272 HRLRKHCKVRFADK--------CADCQEPLLNETSFVEHCLRHSK----DHAHHCPVCRQSLRSD 324

  Fly   556 KLLTKHI---LSHNR-----------------CVHCSMSFTSKYLLEQHT 585
            ..:..|.   :||..                 |..|.......:.|.:||
Worm   325 SQIHAHCAYHMSHQDSTSSTSSSPITNGFSFVCPICGEKLDDGFALIEHT 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17612	NP_608824.1	zf-AD	187..>246	CDD:285071
		C2H2 Zn finger	290..310	CDD:275368	6/31 (19%)
		C2H2 Zn finger	323..343	CDD:275370	4/19 (21%)
		zf-C2H2_8	356..438	CDD:292531	18/84 (21%)
		C2H2 Zn finger	359..379	CDD:275368	6/19 (32%)
		C2H2 Zn finger	394..414	CDD:275368	3/19 (16%)
		C2H2 Zn finger	422..438	CDD:275368	4/15 (27%)
		C2H2 Zn finger	447..463	CDD:275368	5/15 (33%)
		C2H2 Zn finger	476..505	CDD:275368	9/29 (31%)
		C2H2 Zn finger	513..533	CDD:275368	4/19 (21%)
		C2H2 Zn finger	545..565	CDD:275368	4/22 (18%)
		C2H2 Zn finger	568..584	CDD:275368	3/15 (20%)
C09F5.3	NP_001367485.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7952
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950