DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17612 and klu-2

DIOPT Version :9

Sequence 1:	NP_608824.1	Gene:	CG17612 / 33639	FlyBaseID:	FBgn0031597	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_491843.3	Gene:	klu-2 / 172339	WormBaseID:	WBGene00022592	Length:	386	Species:	Caenorhabditis elegans

Alignment Length:	193	Identity:	43/193 - (22%)
Similarity:	87/193 - (45%)	Gaps:	30/193 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   369 SSF--LEIHIQTHEDVSQRLSRKSSHKCAQCADVFSDVS----SLKDHVKIHAGER------TFK 421
            |:|  :..|.|:.|::.||:...:|...:...::.:.:|    :....|:..:|..      .:.
Worm   184 SAFEIVSCHHQSAEEILQRVRLGTSGSTSSANNLRNSLSEATTTTTGSVESTSGTADGSAPGQYY 248

  Fly   422 CPLCLMSFQEESNLKSHDCAHT---RFKCHKCSKFFESQNYLDFHFKKSHTTKGPFKCIKCQQTF 483
            |.:|...|:....|..|...||   .|||..|.:||...::|..| :::||.:.|:.|..|..:.
Worm   249 CFICEKDFRRPDILSRHTRRHTGEKPFKCEDCGRFFSRSDHLRTH-RRTHTDEKPYHCCVCNYSA 312

  Fly   484 QKRNGLKEHISSQVCVQFLRSKSPGQIFPCPKCPKKFSIEDNY---------QMHHATHKKVK 537
            ::|:.|..|:|::     .::.:|..|....:..::...:.:|         |.|.||.::|:
Worm   313 RRRDVLTRHMSTR-----HQAIAPPSILGTHRNVRRCLSDGDYHKMAAQELRQRHQATREEVE 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17612	NP_608824.1	zf-AD	187..>246	CDD:285071
		C2H2 Zn finger	290..310	CDD:275368
		C2H2 Zn finger	323..343	CDD:275370
		zf-C2H2_8	356..438	CDD:292531	15/80 (19%)
		C2H2 Zn finger	359..379	CDD:275368	4/11 (36%)
		C2H2 Zn finger	394..414	CDD:275368	2/23 (9%)
		C2H2 Zn finger	422..438	CDD:275368	4/15 (27%)
		C2H2 Zn finger	447..463	CDD:275368	5/15 (33%)
		C2H2 Zn finger	476..505	CDD:275368	6/28 (21%)
		C2H2 Zn finger	513..533	CDD:275368	4/28 (14%)
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	568..584	CDD:275368
klu-2	NP_491843.3	COG5048	216..>298	CDD:227381	18/82 (22%)
		C2H2 Zn finger	249..269	CDD:275368	5/19 (26%)
		zf-H2C2_2	262..286	CDD:290200	10/23 (43%)
		COG5048	273..>328	CDD:227381	17/60 (28%)
		C2H2 Zn finger	277..297	CDD:275368	6/20 (30%)
		zf-H2C2_2	289..314	CDD:290200	7/25 (28%)
		C2H2 Zn finger	305..324	CDD:275368	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000