Protein Alignment Traf4 and traf2a

DIOPT Version :10

• Sequence 1: NP_477416.1
• Gene: Traf4 / 33638
• FlyBaseID: FBgn0026319
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_073808310.1
• Gene: traf2a / 564295
• ZFINID: ZDB-GENE-071120-2
• Length: 575
• Species: Danio rerio
• Alignment Length: 523
• Identity: 110/523 - (21%)
• Similarity: 183/523 - (34%)
• Gaps: 190/523 - (36%)

  Fly   110 KQGCKWSDELRKLKGHLNACKHDATQCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGA 174
            ||||.:.|         ||.|.:.......|        :.:...:|.|::         |:..
Zfish    86 KQGCAFPD---------NAAKREVEALEAVC--------INEECSWTGTIK---------EYEA- 123

  Fly   175 GLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTLPLHAAQCPR 239
               .|.|.|....:.|.: |.:.:....:..|..::|.:|...|.:|:..|....:..|...||:
Zfish   124 ---NHEGKCDFRILPCPS-CKELLRANELERHNERECPERTLNCKYCKEPFHFKNIKAHDEICPK 184

  Fly   240 APLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLM 304
            .|:.| :.|....|||.:...|:: .|......|.|...||.....::.:..|.::.:..||:|:
Zfish   185 YPMIC-EGCAKKKIPREKYVDHIK-LCTKFRTPCRFHVVGCDMTVEKEKIHDHEQACSYEHLNLL 247

  Fly   305 --------VALSSRQGQQIQM-------------------------------------------- 317
                    |.|.|.|.|.:::
Zfish   248 LHFIMGIKVNLESLQPQSLELASHKIHELHQSLRELELKMGQLCGAGASVQGACALPPPPPPAPT 312

  Fly   318 -------LKSAVS------------------------KLSIN----------------------- 328
                   |.:||.                        :|.:|
Zfish   313 LGTSFTPLPTAVGAALELQLHSEKTKVVELSRRCQELELKVNTFENIVCVLNREMERSATTMEAY 377

  Fly   329 ----------------------------------------------YTGTLLWKITDWSAKMAEA 347
                                                          |.|..:|||:|:|.|..:|
Zfish   378 NRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYDGVFVWKISDFSKKRQDA 442

  Fly   348 RGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFT 412
            .......:.||.||||:||||:...::|||:|.|..||:|::..|:.|..||||||||:..:|..
Zfish   443 VAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLM 507

  Fly   413 LFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSR-PFIKGDTVFLRV 476
            |.:   |:.:..:.::|.||.:..:||||.::.: :..|.|.|.....|.|: .:|:.||:|::.
Zfish   508 LLD---QNNREHIIDAFRPDISSSSFQRPVSDMN-IASGCPLFCPLSKLDSKNSYIRDDTIFIKA 568

  Fly   477 KVD 479
            .||
Zfish   569 IVD 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf4	NP_477416.1	PLN03086	<109..206	CDD:178635	17/95 (18%)
		zf-TRAF	233..292	CDD:280357	15/58 (26%)
		MATH_TRAF4	331..479	CDD:239750	55/148 (37%)
traf2a	XP_073808310.1	None