Protein Alignment Traf4 and traf5

DIOPT Version :10

• Sequence 1: NP_477416.1
• Gene: Traf4 / 33638
• FlyBaseID: FBgn0026319
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_021325328.1
• Gene: traf5 / 563887
• ZFINID: ZDB-GENE-071120-3
• Length: 542
• Species: Danio rerio
• Alignment Length: 571
• Identity: 138/571 - (24%)
• Similarity: 219/571 - (38%)
• Gaps: 176/571 - (30%)

  Fly    52 ATSRSSSSTVSSSHSSSHSSPTPGNNNNNMPITELE-QIIYPGPDPKHIMGSLVFCIHHKQGCKW 115
            |...:.||.:|..:|.:..|....:..... ::.|| |.|.|.      .|.:|. ..|:.||
Zfish     2 AAEENESSGLSRQNSEASRSWDLDSRTLRF-VSRLEQQFICPS------CGGIVL-NPHQTGC-- 56

  Fly   116 SDELRKLKGHLNACKHDATQC---------PNKCGAQIPRIMMTDHLQYTCTMRR--------TR 163
                    ||: .|    .||         .:||......|...:..|..|..|.        |.
Zfish    57 --------GHI-FC----AQCVKAYTENGGSSKCPLDSIPIKPEEIFQDNCCKRELLNLEVFCTN 108

  Fly   164 CEFCQSEFSGAGLEEHNGSCGQEPVYC-EAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSA 227
            ...|...||...|::|..:|..|.|.| .:.|...:||..:..|:...|:.||..|.:|::.|..
Zfish   109 APECTQRFSLCNLQDHLKACPHERVRCSHSDCSDIVLRKNLLEHQRNACSYRLETCHYCRQNFPV 173

  Fly   228 DTLPLH-AAQCPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEA 291
            ..:..| .:.||...:.|...| ...|.|.:|:|| .|||..:...|.:|..||..:..|..::.
Zfish   174 SQMMGHQKSSCPDVEVPCSNNC-TQMIKRHQLQAH-ADECLEVETDCVYKNYGCTVRDKRGKVQV 236

  Fly   292 HLESNAAAHLSLMVALSSRQGQQIQMLKS--------------AVSKL----------------- 325
            |..:..:||:.|::..:::..:|::.|:.              .||.|
Zfish   237 HENTEFSAHVRLVLESNTKLEKQMEQLQQDMLVQQGVLKDKSLVVSSLDRDVSLCDNTLTTLQRS 301

  Fly   326 ----------------------------------------------------------------- 325
                                                                             
Zfish   302 VEEQRVRICSVQRELRDLRVLGSELKEELPRLQASLDSLRQQVAVTESLREHLGALEQTCERHTR 366

  Fly   326 --------------------SINYTGTLLWKITD-WSAKMAEARGKDGLELVSPPFYTSQYGYKL 369
                                |.:|.|.|:||:.| |..|      :.|..|.|.|||||:.||||
Zfish   367 LLDIHVEQLQCNEQRLRQLESSSYDGKLIWKVRDYWHRK------ESGAALSSSPFYTSRSGYKL 425

  Fly   370 QASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSG-QGGVAESFVPDP 433
            ....:|.|:|.|..:|:|:||.::.|::|:.|.|||..:||.||.:   ||| :..::.:|:||.
Zfish   426 SVRAYLGGDGSGRGSHMSLYITIMRGDFDSFLPWPFRQNITLTLLD---QSGTRNHMSHTFIPDV 487

  Fly   434 TWENFQRPSNEPDQLGFGFPRFISH---ELLHSRPFIKGDTVFLRVKVDPS 481
            ..::|.||:::.: :..||.|||||   |...:..|::.:|:|::||||.|
Zfish   488 NSDSFHRPTSDAN-VATGFTRFISHCDLENPRNAVFVRDETLFIKVKVDTS 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf4	NP_477416.1	PLN03086	<109..206	CDD:178635	27/114 (24%)
		zf-TRAF	233..292	CDD:280357	18/59 (31%)
		MATH_TRAF4	331..479	CDD:239750	59/152 (39%)
traf5	XP_021325328.1	RING_Ubox	35..90	CDD:473075	18/76 (24%)
		zf-TRAF	124..179	CDD:280357	15/54 (28%)
		zf-TRAF	179..237	CDD:280357	18/59 (31%)
		SMC_prok_B	<192..>384	CDD:274008	23/193 (12%)
		MATH_TRAF_C	392..535	CDD:238168	59/152 (39%)