Protein Alignment Traf4 and traf6

DIOPT Version :9

• Sequence 1: NP_477416.1
• Gene: Traf4 / 33638
• FlyBaseID: FBgn0026319
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001038217.1
• Gene: traf6 / 554561
• ZFINID: ZDB-GENE-030131-5735
• Length: 542
• Species: Danio rerio
• Alignment Length: 563
• Identity: 130/563 - (23%)
• Similarity: 200/563 - (35%)
• Gaps: 171/563 - (30%)

  Fly    16 SRLSPNRNSKDCSTLASPVPPP--------TPP--------------RNKTTSGSGNCATSRSSS 58
            |.|||..|....| ::|.:||.        .||              |:...:..|:    |...
Zfish    33 SFLSPTENPSTIS-VSSSMPPDQQGYDVEFDPPLESKYECPICLMGLRSAVQTPCGH----RFCD 92

  Fly    59 STVSSSHSSSHSSPTPGNNNNNMPITELEQIIYPGPDPK-HIMGSLVFCIHHKQGCKWSDELRKL 122
            |.:..|...: ....|.:|.     ..||:.::|....| .|:...|.|.:.  ||....|||:|
Zfish    93 SCIRKSIRDT-GQKCPVDNE-----VLLEEQLFPDNFAKREILSLTVKCSNF--GCSEKMELRQL 149

  Fly   123 KGHLNACKHDATQCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEHNGSCGQEP 187
            :.||:.|:.....|| :|...:|...:.:|....|..|...|..|...|..|..:.|...|....
Zfish   150 EKHLSQCRFATAPCP-QCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYAVKQNHEQFCPFAN 213

  Fly   188 VYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTLPLHAAQCPRAPLACPQRCDAGP 252
            ..||                            :|:.|...|.|.||              ||.
Zfish   214 TVCE----------------------------YCEMELIRDQLALH--------------CDT-- 234

  Fly   253 IPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLES---------------------- 295
                        :|....|:|:|...|||.|..|..|..|::.
Zfish   235 ------------DCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCT 287

  Fly   296 --NAAAHLS-------------------------LMVALSS---RQGQQIQML-------KSAVS 323
              :||||||                         .::.|..   ||.|||:.|       |:.|:
Zfish   288 MPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVT 352

  Fly   324 KL---------------SINYTGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASM 373
            :|               :..|.|..:|::.::|..:........:.|.||||||.:.||||...:
Zfish   353 ELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRL 417

  Fly   374 FL-NGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWEN 437
            .| ..:.|..:..:|:::..:.||:|:.|.||...:|...:.:|  ..||..: |.....|..:.
Zfish   418 HLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQ--VEGQHHI-EVMETKPDLQA 479

  Fly   438 FQRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKVDP 480
            ||||:...:..|||:..|:..:.|..|.|:|.|.:.:|.:|.|
Zfish   480 FQRPTVMRNPKGFGYVTFLHLQALRQRGFVKEDVLLVRCEVTP 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf4	NP_477416.1	PLN03086	<109..206	CDD:178635	24/96 (25%)
		zf-TRAF	233..292	CDD:424248	13/58 (22%)
		MATH_TRAF4	331..479	CDD:239750	43/148 (29%)
traf6	NP_001038217.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..54		9/21 (43%)
		RING	71..108	CDD:214546	5/41 (12%)
		zf-TRAF	205..262	CDD:280357	22/112 (20%)
		MATH_TRAF6	375..521	CDD:239745	43/148 (29%)
		Substrate binding. /evidence=ECO:0000250	489..496		3/6 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391991at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920