DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Traf4 and elgi

DIOPT Version :9

Sequence 1:	NP_477416.1	Gene:	Traf4 / 33638	FlyBaseID:	FBgn0026319	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001261904.1	Gene:	elgi / 39735	FlyBaseID:	FBgn0283649	Length:	315	Species:	Drosophila melanogaster

Alignment Length:	241	Identity:	47/241 - (19%)
Similarity:	80/241 - (33%)	Gaps:	61/241 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 PTPGNNNNNMPITELEQIIYPGPDPKHIMGSL----VFCIHHKQGCKWSDELRKLKGHLNACKHD 132
            ||...:.|::....|..:      |:.:...|    :.|.:...||....:|.....||:.|.|:
  Fly    51 PTCPVDRNSLTTANLRAV------PRILRNLLSRLSITCDNAPYGCTAVLKLDAYNSHLDECIHN 109

  Fly   133 ATQ---CPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEHNGSCGQEPVYCEAKC 194
            ..:   |...||..||:..:.||   .|..........|:|..|   |..:....|:....|.|
  Fly   110 PKRPFPCEKGCGFDIPKDELKDH---NCVRELRTLIVKQTEKMG---ELKSELTDQQLTINELK- 167

  Fly   195 GQRILRGRMTLHKSKDCAKRLRRCAHCQR----EFSADTLPLHAAQCPRA-------PLACPQRC 248
                    ..|...||..:.:|......|    :...|.:...::..|||       .::.|
  Fly   168 --------RELQLFKDFMRAMRVSNPAMRAIADQMERDEVIRWSSTLPRARVTRWGGMISTP--- 221

  Fly   249 DAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLE 294
                           |:...|.:..:..|:||    |..:|::.:|
  Fly   222 ---------------DDALQLMIKRALSESGC----PPHILDSLME 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf4	NP_477416.1	PLN03086	<109..206	CDD:178635	22/99 (22%)
		zf-TRAF	233..292	CDD:424248	11/65 (17%)
		MATH_TRAF4	331..479	CDD:239750
elgi	NP_001261904.1	RING	17..55	CDD:238093	2/3 (67%)
		Sina	83..>157	CDD:302762	20/79 (25%)
		USP8_interact	137..315	CDD:286082	25/146 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010