Protein Alignment Traf4 and Traf2

DIOPT Version :10

• Sequence 1: NP_477416.1
• Gene: Traf4 / 33638
• FlyBaseID: FBgn0026319
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001101285.1
• Gene: Traf2 / 311786
• RGDID: 1310457
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 477
• Identity: 120/477 - (25%)
• Similarity: 199/477 - (41%)
• Gaps: 88/477 - (18%)

  Fly    45 TSGSGNCATSRSSSSTVSSSHSSSHSSPTPGNNNNNMPITELEQIIYPGPDPKHIMGSLVFCIHH 109
            :||..|||.................||..|    :|....|:|.:  |...|
  Rat    63 SSGPQNCAACVHEGLYEEGISILESSSAFP----DNAARREVESL--PAVCP------------- 108

  Fly   110 KQGCKWSDELRKLKG-HLNACKHDATQCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSG 173
            ..||.|...|::.:. |...|....|:|| .|...:.......|.:..|..|...|:.|::..|.
  Rat   109 NDGCTWKGTLKEYESCHEGLCPFLLTECP-ACKGLVRLSEKKHHTEQECPKRSLSCQHCRAPCSH 172

  Fly   174 AGLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTLPLHAAQCP 238
            |.||.|...|.:.|:.|:. ||::|.:.::..|        :|.|:.|:            ..|.
  Rat   173 ADLELHYEVCPKFPLTCDG-CGKKISQEKLQDH--------VRTCSKCR------------VLCR 216

  Fly   239 RAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAH-LESNAAAHLS 302
            ...:.|.:..:...:...||: .||:....|..|....:|.....||..:.... ||...|...:
  Rat   217 FHAIGCSELVETEDLQDHELQ-RLREHLALLLSSFLESQASQNQVGPELLQRCQILEQKIATFEN 280

  Fly   303 LMVALS-------------SRQG--------------QQIQM-----------LKSAVSKLSIN- 328
            ::..|:             |||.              ||::.           |:..||:|.::
  Rat   281 IVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVST 345

  Fly   329 YTGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVL 393
            |.|..:|||:|::.|..||.......:.||.|:||:||||:...::|||:|.|..||:|::..|:
  Rat   346 YDGVFIWKISDFARKRQEAIAGRTPAIFSPAFFTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVM 410

  Fly   394 PGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISH 458
            .|..||||:|||:..:|..|.:   .:.:..|.::|.||.|..:||||.::.: :..|.|.|...
  Rat   411 KGPNDALLQWPFNQKVTLMLLD---HNNREHVIDAFRPDVTSSSFQRPVSDMN-IASGCPLFCPV 471

  Fly   459 ELLHSR-PFIKGDTVFLRVKVD 479
            ..:.:: .:::.|.:|::..||
  Rat   472 SKIEAKNSYVRDDAIFIKAIVD 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf4	NP_477416.1	PLN03086	<109..206	CDD:178635	26/97 (27%)
		zf-TRAF	233..292	CDD:280357	11/58 (19%)
		MATH_TRAF4	331..479	CDD:239750	50/148 (34%)
Traf2	NP_001101285.1	RING-HC_TRAF2	31..73	CDD:438301	5/9 (56%)
		zf-TRAF	178..234	CDD:280357	13/76 (17%)
		TRAF_BIRC3_bd	263..326	CDD:465226	9/62 (15%)
		MATH_TRAF2	330..493	CDD:239747	55/166 (33%)