Protein Alignment Traf4 and Traf1

DIOPT Version :10

• Sequence 1: NP_477416.1
• Gene: Traf4 / 33638
• FlyBaseID: FBgn0026319
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_033447.2
• Gene: Traf1 / 22029
• MGIID: 101836
• Length: 409
• Species: Mus musculus
• Alignment Length: 434
• Identity: 100/434 - (23%)
• Similarity: 162/434 - (37%)
• Gaps: 152/434 - (35%)

  Fly   172 SGAGLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKS-KDCAKRLRRCAHCQREFSADTLPLHAA 235
            |.:..:|:....|..|..|:.....|:|.....|.:: :|...|:  |..|:    ||.  ||..
Mouse     3 SSSAPDENEFQFGCPPAPCQDPSEPRVLCCTACLSENLRDDEDRI--CPKCR----ADN--LHPV 59

  Fly   236 QCPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAH 300
            . |.:||.               :..:..:.....:.|.|...||.|||..|.::.|..::.::|
Mouse    60 S-PGSPLT---------------QEKVHSDVAEAEIMCPFAGVGCSFKGSPQSMQEHEATSQSSH 108

  Fly   301 LSLMVAL--------SSRQGQQIQMLKSAVSKLSI------------------------------ 327
            |.|::|:        .|..|.....|:..:|:|.:
Mouse   109 LYLLLAVLKEWKSSPGSNLGSAPMALERNLSELQLQAAVEATGDLEVDCYRAPCCESQEELALQH 173

  Fly   328 ----------------------------------------------------------------- 327
                                                                             
Mouse   174 LVKEKLLAQLEEKLRVFANIVAVLNKEVEASHLALAASIHQSQLDREHILSLEQRVVELQQTLAQ 238

  Fly   328 ------------------NYTGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMF 374
                              ::.||.|||||:.:.:..|:.....:.|.||.|||::|||||...::
Mouse   239 KDQVLGKLEHSLRLMEEASFDGTFLWKITNVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLY 303

  Fly   375 LNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQ 439
            |||:|.|:.||:|::|.::.|||||||.|||.:.:||.|.:   |:.:....::|.||.:..:||
Mouse   304 LNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLD---QNNREHAIDAFRPDLSSASFQ 365

  Fly   440 RPSNEPDQLGFGFPRFISHELLHS--RPFIKGDTVFLRVKVDPS 481
            ||.:|.: :..|.|.|.....|.|  ..::|.||:||:..||.|
Mouse   366 RPQSETN-VASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVDTS 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf4	NP_477416.1	PLN03086	<109..206	CDD:178635	7/33 (21%)
		zf-TRAF	233..292	CDD:280357	12/58 (21%)
		MATH_TRAF4	331..479	CDD:239750	60/149 (40%)
Traf1	NP_033447.2	TRAF_BIRC3_bd	175..238	CDD:465226	0/62 (0%)
		MATH_TRAF1	260..406	CDD:239748	60/149 (40%)