Protein Alignment Traf4 and trf-1

DIOPT Version :10

• Sequence 1: NP_477416.1
• Gene: Traf4 / 33638
• FlyBaseID: FBgn0026319
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_499773.2
• Gene: trf-1 / 176767
• WormBaseID: WBGene00006612
• Length: 462
• Species: Caenorhabditis elegans
• Alignment Length: 439
• Identity: 105/439 - (23%)
• Similarity: 169/439 - (38%)
• Gaps: 91/439 - (20%)

  Fly    76 NNNNNMPITELEQIIYP------GPDPKHIMGSLVFCIHHKQGCKWSDELRKLKGHLNACKHDAT 134
            |.|........:.||.|      ....|.|:...|.|.....||.|..:|..|..||:.|...::
 Worm    44 NENRTPGCAACQTIIQPELCQHDRAKQKQILALPVVCTFESSGCPWDGQLGTLHDHLSECTFKSS 108

  Fly   135 QCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEHNGSCGQEPVYCEAKCGQRIL 199
                                       .:||.|..:|:...||:|...|
 Worm   109 ---------------------------LKCEKCGRQFAKNDLEKHRAKC---------------- 130

  Fly   200 RGRMTLHKSKDCAKRLRR--CAHCQREFSADTLPLHAAQCPRAPLACPQRCDAGPIPRGELEAHL 262
                          .|.|  |:.|.:.........|...||:..::||.:|.....||.|:|||.
 Worm   131 --------------ELNRAVCSFCNKTIRDSDRERHPKTCPQVIISCPFQCGLTDRPRLEIEAHC 181

  Fly   263 RDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMV---------------ALSSRQG 312
             ..|.::...|.|...||.|.|.::.::.||......||..:.               .:.|...
 Worm   182 -PSCPNVDNVCPFVPYGCTFAGGKESIQQHLSDEPVRHLMYLCDEITDLKGTYELMERDMGSFND 245

  Fly   313 QQIQMLKSAVSKLSINYTGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNG 377
            :|.::| ||....:..:...|:|||.....:..||:......:.|.||.:.::|||:.|...|.|
 Worm   246 RQTRIL-SAAETCTEMFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFG 309

  Fly   378 NGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDP----TWENF 438
            :|......:|:|:.:|.||:|..|:|||..:|..:|.:|..:. :..|..::|.||    ..|.|
 Worm   310 DGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRP-EDRVNITYVIDPRKLKANEKF 373

  Fly   439 -QRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKVDPSKIVAV 486
             .||..|.: ..||...|.|..:|.:  ::|.|.:::::.||..:.:.|
 Worm   374 LARPRGERN-AAFGSQSFCSLAILQN--YVKDDKIYVQIDVDRCETLPV 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf4	NP_477416.1	PLN03086	<109..206	CDD:178635	16/96 (17%)
		zf-TRAF	233..292	CDD:280357	19/58 (33%)
		MATH_TRAF4	331..479	CDD:239750	45/152 (30%)
trf-1	NP_499773.2	RING_Ubox	15..61	CDD:473075	4/16 (25%)
		zf-TRAF	152..210	CDD:280357	19/58 (33%)
		MATH_TRAF_C	264..412	CDD:238168	45/151 (30%)