Protein Alignment Traf4 and traf3

DIOPT Version :9

• Sequence 1: NP_477416.1
• Gene: Traf4 / 33638
• FlyBaseID: FBgn0026319
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_002938036.2
• Gene: traf3 / 100498216
• XenbaseID: XB-GENE-968262
• Length: 569
• Species: Xenopus tropicalis
• Alignment Length: 620
• Identity: 150/620 - (24%)
• Similarity: 235/620 - (37%)
• Gaps: 220/620 - (35%)

  Fly     3 RSLAQWTKTLSFPSR-------LSPNRNSKDCS----TLASPVPPPTPPRNKTTSGSGNCATSRS 56
            ||||   .|:..|.:       |.|......|.    .|.:|        .:|..|...|.|..:
 Frog    28 RSLA---TTIYVPEQGGYKERFLKPVEEKYKCEKCRLVLCNP--------RQTECGHRFCETCMN 81

  Fly    57 S--SSTVSSSHSSSHSSPTPGNNNNNMPITELEQIIYPGPDPKHIMGSLVFCIHHKQGCKWSDEL 119
            :  |||          ||......:|  ||: :::.......:.::...:||.:..:|||....|
 Frog    82 AILSST----------SPQCMACEDN--ITK-DKVFKDNCCRREVLALQMFCRNETRGCKELITL 133

  Fly   120 RKLKGHLNA-CKHDATQCPN-KCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEHNGS 182
            ..|..||.: |:.:...||. .|..::.|..::||::.||..|.|.|:||:::.....:::|..
 Frog   134 GNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKHED- 197

  Fly   183 CGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTLPLHAAQCPRAPLACPQR 247
                                                                ..||...::||..
 Frog   198 ----------------------------------------------------VDCPSVVISCPHM 210

  Fly   248 CDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLM-------- 304
            |....:.|.||.|||. ||.:...:||||..||.|||..|.::||..|:|..|::||
 Frog   211 CSVKSLLRSELNAHLL-ECVNAPSTCSFKRYGCTFKGTNQQIKAHEASSAVQHVNLMKEWSNYLE 274

  Fly   305 --VAL----SSRQGQQIQML--------------------------------------------- 318
              |::    ||.:.:.||:|
 Frog   275 AKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKE 339

  Fly   319 --------------------------------KSAVS---------------KLSI--------- 327
                                            |:|.|               .||:
 Frog   340 IRNLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMD 404

  Fly   328 ---------NYTGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGEN 383
                     :|.|.|:|||.|:..:..||.....|.|.|.||||..:|||:.|.::|||:|.|:.
 Frog   405 LRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKG 469

  Fly   384 THVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQL 448
            ||:|::..::.|||||||.|||...::..|.:||......|  ::|.|||...:|::|:.|.: :
 Frog   470 THLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLG--DAFKPDPNSSSFKKPTGEMN-I 531

  Fly   449 GFGFPRFISHELLHSRPFIKGDTVFLRVKVDPSKI 483
            ..|.|.|::..:|.:..:||.||:|::|.||.|.:
 Frog   532 ASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDL 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf4	NP_477416.1	PLN03086	<109..206	CDD:178635	22/98 (22%)
		zf-TRAF	233..292	CDD:424248	23/58 (40%)
		MATH_TRAF4	331..479	CDD:239750	58/147 (39%)
traf3	XP_002938036.2	RING-HC_TRAF3	54..95	CDD:319554	12/58 (21%)
		RING-HC finger (C3HC4-type)	56..94	CDD:319554	12/55 (22%)
		zf-TRAF	139..195	CDD:280357	16/55 (29%)
		zf-TRAF	200..250	CDD:280357	22/50 (44%)
		Smc	<255..>372	CDD:224117	11/116 (9%)
		MATH_TRAF3	382..564	CDD:239746	63/184 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391991at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3301
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950