DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15429 and Cyb5r4

DIOPT Version :9

Sequence 1:	NP_608823.2	Gene:	CG15429 / 33637	FlyBaseID:	FBgn0031596	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_596918.3	Gene:	Cyb5r4 / 171015	RGDID:	621834	Length:	520	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	56/247 - (22%)
Similarity:	89/247 - (36%)	Gaps:	65/247 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KDEVVSHNKKDDCWVIIHRNIYDLTPMLKDRFDNWNRTLDYLVAHAGKDLTHFFHE-----NGEP 72
            ::|:..||||||||:.|...:|:::|.::.....    .|.|:..||.|.|..|:|     |.|.
  Rat    59 EEELKKHNKKDDCWICIRGFVYNVSPYMEYHPGG----EDELMRAAGADGTDLFNEVHRWVNYES 119

  Fly    73 --------RTEISPSTGR-----PRVL---FP--PILEVAISEFCKTPGEMWSQDPFYHIGTVTK 119
                    |..:.|:..:     .|||   .|  .:.:....|...:|...|.|         |:
  Rat   120 MLKECLVGRMAVKPAVPKDCHEGKRVLNGMLPKSQVTDTLPREGPSSPSYDWFQ---------TE 175

  Fly   120 RARLIRIVNTLTAQTQYMTVCNEDSIYDIQQK--------YKQRYNHHAG-------SYEWRKFS 169
            .:      .|:...|:...:..:..|.|:|..        ....|..|.|       ::..|...
  Rat   176 SS------VTIVIYTKQKNINLDSVIVDLQDDSLRAEAVIKDHSYLIHIGLSHEVQENFSVRVIE 234

  Fly   170 NGGKSCSILNLNGTLDENGLTDD-EDSNVELPPPSIWLYY-------TDDIT 213
            |.||...:|....|:....|.|. |..:..:|.....|||       .:|:|
  Rat   235 NVGKIEIVLQKKETVSWKCLGDPLEKHDSFIPKKDTGLYYRQCQLISKEDVT 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15429	NP_608823.2	Cyt-b5	10..>70	CDD:278597	20/61 (33%)
Cyb5r4	NP_596918.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		Cyt-b5	56..128	CDD:278597	22/72 (31%)
		p23_NCB5OR	169..255	CDD:107240	17/100 (17%)
		cyt_b5_reduct_like	277..518	CDD:99780	2/10 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5274
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900