Protein Alignment Atet and ABCG1

DIOPT Version :9

• Sequence 1: NP_001097079.1
• Gene: Atet / 33636
• FlyBaseID: FBgn0020762
• Length: 832
• Species: Drosophila melanogaster
• Sequence 2: XP_024307909.1
• Gene: ABCG1 / 9619
• HGNCID: 73
• Length: 786
• Species: Homo sapiens
• Alignment Length: 680
• Identity: 344/680 - (50%)
• Similarity: 448/680 - (65%)
• Gaps: 95/680 - (13%)

  Fly   156 DSHRRGFKTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGYKTAQLSGSVLINSKERNLRRF 220
            |....|:||:||.:||||.:||:.||||||||||||||||||||:...:.|:||||...|:||.|
Human   199 DPMEEGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCF 263

  Fly   221 RKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEILETIGLKESVNTLTCNLS 285
            ||:||||||||:|:.:|||:|||||:|:|||.:.  ...:..:|:|||..:||....||.|.:||
Human   264 RKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEK--DEGRREMVKEILTALGLLSCANTRTGSLS 326

  Fly   286 GGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEK 350
            |||||||:|||||||||||||||||||||||::|||::||::.||:|||:|:||||||||:|||.
Human   327 GGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFEL 391

  Fly   351 FDHLYLLAQGQCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYGDAVPKLVDAVKSGA 415
            ||.||:|:||||||.|:|..|||||..||..||:||||||:|:|||||||||...:||.||:.|.
Human   392 FDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGM 456

  Fly   416 CKKYAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKP 480
                             |::|..:..|..||          ..|.|..|   ||..|.....||
Human   457 -----------------CDSDHKRDLGGDAE----------VNPFLWHR---PSEEVKQTKRLK- 490

  Fly   481 PKLETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVV 545
             .|....|....|.             |||:|                    |:
Human   491 -GLRKDSSSMEGCH-------------SFSAS--------------------CL----------- 510

  Fly   546 TLPNKTGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSN 610
                         |||.||.||:|.:|:||.:|||:|:.||:.:|.:||::|..:||||.|::||
Human   511 -------------TQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSN 562

  Fly   611 AGCIFFVSLFTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVL 675
            :|.:||..||..|.|:|||:||||.||.||:||||||||||||:|.|||:||:||||:|...|..
Human   563 SGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCS 627

  Fly   676 VVYYLTSQPMELERVSMFVLICVLNSLVAQSLGLLIG-AGMNIETGVFLGPVTTIPTILFSGFFV 739
            :||::||||.:..|..:|..:..:.|||||||||||| |..:::...|:||||.||.:|||||||
Human   628 IVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFV 692

  Fly   740 NFDTIPGYLQWVTYVSYVRYGFEGAMVAIYGMDRAKMQCN-QMYCHYRVPKKFLEEMSMDNALFW 803
            :|||||.||||::|:|||||||||.:::|||:||..:.|: ...||::..:..|.|:.::||..:
Human   693 SFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLY 757

  Fly   804 VDAVALIGIFF-ALRIIAYFVLRWKLHMIR 832
            :|.:.| |||| :||:|||||||:|:...|
Human   758 LDFIVL-GIFFISLRLIAYFVLRYKIRAER 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	340/671 (51%)
		ABCG_EPDR	142..366	CDD:213180	138/209 (66%)
		ABC2_membrane	564..767	CDD:279410	120/203 (59%)
ABCG1	XP_024307909.1	3a01204	202..786	CDD:273361	342/675 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141410
Domainoid	1	1.000	270	1.000	Domainoid score	I1842
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	696	1.000	Inparanoid score	I684
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.760