DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG24

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_175745.4	Gene:	ABCG24 / 841775	AraportID:	AT1G53390	Length:	1109	Species:	Arabidopsis thaliana

Alignment Length:	755	Identity:	194/755 - (25%)
Similarity:	305/755 - (40%)	Gaps:	181/755 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 CSSHAVILPAAKSPNRVSDSAATTAPNAVLYTSGNMSLSTLSTGSGNPNPNPNASTNSRQEPVPL 79
            |||     ||:.|   .:.|:.....:|...::|..||       |.........|
plant   413 CSS-----PASSS---AAQSSYENEDHAAAGSNGRASL-------GIEGKRVKGQT--------- 453

  Fly    80 LSQLKLTNDL----------KQNSHGSQN-NLCNGGLGSNNHALAPKVANNSGGSPNGQKKGTIA 133
            |:::|.|...          |:.:...:| ||...|:        .|:|.||    ..:|:
plant   454 LAKIKKTQSQIFKYAYDRIEKEKAMEQENKNLTFSGI--------VKMATNS----ETRKR---- 502

  Fly   134 LSHLPQRPPVDIEFCDISYSVTDSHRRGFKTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAG 198
              ||     :::.|.|::.::    :...|.:|:.|:|..:.|.|||:||||||||::|::.|||
plant   503 --HL-----MELSFKDLTLTL----KSNGKQVLRCVTGSMKPGRITAVMGPSGAGKTSLLSALAG 556

  Fly   199 YKT-AQLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVV 262
            ... .:|||.:|||.|:.::..::|:..::.||||:..||||.|.:...|..:|..::....||:
plant   557 KAVGCKLSGLILINGKQESIHSYKKIIGFVPQDDVVHGNLTVEENLWFHAKCRLPADLSKADKVL 621

  Fly   263 VVEEILETIGLKESVNTLT-----CNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQL 322
            |||.|::::||:...::|.     ..:|||||||:::.||:|..|.|:|.|||||||||::...|
plant   622 VVERIIDSLGLQAVRSSLVGTVEKRGISGGQRKRVNVGLEMVMEPSVLFLDEPTSGLDSASSQLL 686

  Fly   323 ISLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQ-GQCVYEGRVKGLVPYLSSLGYECPSYH 386
            :..||..|..|..|...:||||..||:.|:.|.|||: |..||.|.|..:..|.|.||...|...
plant   687 LRALRHEALEGVNICMVVHQPSYTLFKTFNDLVLLAKGGLTVYHGSVNKVEEYFSGLGIHVPDRI 751

  Fly   387 NPADYVLEVASGEYGDAVPKLVDAVKSGACKK------YAHKDYVLTLAQKGCNNDIIKGSGSGA 445
            ||.||.::|..|       .::....||...|      ..||.|.:.|       |:...|.:|.
plant   752 NPPDYYIDVLEG-------VVISMGNSGIGYKELPQRWMLHKGYSVPL-------DMRNNSAAGL 802

  Fly   446 ENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQNSDCSVVNMPTNAVDDSCSFS 510
            |.                                .|.|.|....|::.:........|..:....
plant   803 ET--------------------------------NPDLGTNSPDNAEQTFARELWRDVKSNFRLR 835

  Fly   511 SSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTSGWTQFWILLKRSFRTILRD 575
            ..|...|               .:.|...||...          .|.|.|:...|.|..:..:|:
plant   836 RDKIRHN---------------FLKSRDLSHRRT----------PSTWLQYKYFLGRIAKQRMRE 875

  Fly   576 KMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSNAGCIFFVSLFTTFTAMMPTILTFPTEMSVF 640
            ..|........::.||.:|.: ....:|:.........|..|||.....|:..           |
plant   876 AQLQATDYLILLLAGACLGSL-IKASDESFGAPGYIYTIIAVSLLCKIAALRS-----------F 928

  Fly   641 VREHLNYW------YSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTSQPMELERVSMFVLICVL 699
            ..:.|:||      .|..|.:.||...|: |.|:...:..|.::|..:.|......:..||:|::
plant   929 SLDKLHYWRESASGMSSSACFLAKDTIDI-FNILVKPLVYLSMFYFFTNPRSTFFDNYIVLVCLV 992

  Fly   700 NSLVAQSLGLLIGAGMNIETGVFLGPVTT------IPTIL 733
            ..:          .|:.....:||.|.|.      :|.:|
plant   993 YCV----------TGIAYALAIFLQPSTAQLFSVLLPVVL 1022

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	167/622 (27%)
		ABCG_EPDR	142..366	CDD:213180	92/230 (40%)
		ABC2_membrane	564..767	CDD:279410	37/182 (20%)
ABCG24	NP_175745.4	EcfA2	504..736	CDD:224047	95/240 (40%)
		ABCG_EPDR	505..731	CDD:213180	92/229 (40%)
		ABC2_membrane	867..>1006	CDD:304374	30/161 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810