DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG11

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_173226.2	Gene:	ABCG11 / 838363	AraportID:	AT1G17840	Length:	703	Species:	Arabidopsis thaliana

Alignment Length:	751	Identity:	213/751 - (28%)
Similarity:	343/751 - (45%)	Gaps:	156/751 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 VANNSGGSPNGQKKGTIALSHLPQRPPVDIEFC----------DISYSVT--DSHRRGFKTILKS 168
            |:...|..|.|   |...||....|.....||.          |::..||  |...   :.:|:.
plant    14 VSVGGGNFPVG---GLSPLSEAIWREKAPTEFVGDVSARLTWQDLTVMVTMGDGET---QNVLEG 72

  Fly   169 VSGKFRNGEITAIMGPSGAGKSTLMNILAGYKTAQ--LSGSVLINSKERNLRRFRKLS----CYI 227
            ::|....|.:||:|||||:||||:::.||....|.  |||:||:|.::      .|||    .|:
plant    73 LTGYAEPGSLTALMGPSGSGKSTMLDALASRLAANAFLSGTVLLNGRK------TKLSFGTAAYV 131

  Fly   228 MQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEILETIGLKESVNTLTCN-----LSGG 287
            .|||.||..|||||.:..:|.::|...|:...|..:||..:..:||::..:|:..|     :|||
plant   132 TQDDNLIGTLTVRETIWYSARVRLPDKMLRSEKRALVERTIIEMGLQDCADTVIGNWHLRGISGG 196

  Fly   288 QRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEKFD 352
            :::|:|||||::..|.::|.|||||||||::.|.:...||:|:|.|||::.:|||||:.:||.||
plant   197 EKRRVSIALEILMRPRLLFLDEPTSGLDSASAFFVTQTLRALSRDGRTVIASIHQPSSEVFELFD 261

  Fly   353 HLYLLAQGQCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYGDAVPKLVDAVKSGACK 417
            .||||:.|:.||.|:......:.:..|:.||:..||:|:.|...:.::        |.|::
plant   262 RLYLLSGGKTVYFGQASDAYEFFAQAGFPCPALRNPSDHFLRCINSDF--------DKVRA---- 314

  Fly   418 KYAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPK 482
                               .:|||       |.:             :.|.|   |||.|    |
plant   315 -------------------TLKGS-------MKL-------------RFEAS---DDPLE----K 333

  Fly   483 LETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTL 547
            :.|.::       :.:..:....|..:.::|.....:        |...|   ::|||
plant   334 ITTAEA-------IRLLVDYYHTSDYYYTAKAKVEEI--------SQFKG---TILDS------- 373

  Fly   548 PNKTGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSNAG 612
               .|...|...|.:.|.||||..:.||.....:||..:::|...||.||.:||...|.|::...
plant   374 ---GGSQASFLLQTYTLTKRSFINMSRDFGYYWLRLLIYILVTVCIGTIYLNVGTSYSAILARGS 435

  Fly   613 CIFFVSLFTTFTAM--MPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVL 675
            |..||..|.||.::  .|   :|..:|.||.||.||..|.:.||..|.|::..||.|:.:.:...
plant   436 CASFVFGFVTFMSIGGFP---SFVEDMKVFQRERLNGHYGVAAFVIANTLSATPFLIMITFISGT 497

  Fly   676 VVYYLTSQPMELERVSMFVLICVLNSLVAQSL-------------GLLIGAGMNIETGVFLGPVT 727
            :.|::............|||....:..|.:||             |::||||:.   |:|:
plant   498 ICYFMVGLHPGFTHYLFFVLCLYASVTVVESLMMAIASIVPNFLMGIIIGAGIQ---GIFM---- 555

  Fly   728 TIPTILFSGFFVNFDTIPGYLQWVTYVSYVRYGFEGAMVAIYGMDRAKMQCNQMYCHYRVPKKFL 792
                 |.||||...:.||... |...:||:.:.| .|:...|..|...:..:.....:::|.:::
plant   556 -----LVSGFFRLPNDIPKPF-WRYPMSYISFHF-WALQGQYQNDLRGLTFDSQGSAFKIPGEYV 613

  Fly   793 EEMSMDNALF---WVDAVALIGIFFALRIIAYFVLR 825
            .|......|.   |::...::.:....|||.:.:::
plant   614 LENVFQIDLHRSKWINLSVILSMIIIYRIIFFIMIK 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	206/728 (28%)
		ABCG_EPDR	142..366	CDD:213180	97/246 (39%)
		ABC2_membrane	564..767	CDD:279410	67/217 (31%)
ABCG11	NP_173226.2	3a01204	66..601	CDD:273361	192/646 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810