DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG28

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_200882.4	Gene:	ABCG28 / 836195	AraportID:	AT5G60740	Length:	1109	Species:	Arabidopsis thaliana

Alignment Length:	788	Identity:	198/788 - (25%)
Similarity:	327/788 - (41%)	Gaps:	187/788 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 LSTLSTGSGNPNPNPNASTNSRQEPVPLLSQLKLT---NDLKQNSHGSQN-NLCNGGLGSNNHAL 112
            ||....||....| |...::|..:......:.|||   :|::||....:. ||..|......||.
plant   382 LSQAKPGSDAALP-PMLGSSSDTKKGKKKEKNKLTEMLHDIEQNPEDPEGFNLEIGDKNIKKHAP 445

  Fly   113 APKVANNSG-------GSPNGQK-----------KGTIALSH---LPQRPPVDIEFCDISYSVTD 156
            ..|..:...       |....:|           .|.|::::   :.:||.:::.|.|:|.::..
plant   446 KGKALHTQSQMFRYAYGQIEKEKAMQEQNKNLTFSGVISMANDIDIRKRPMIEVAFKDLSITLKG 510

  Fly   157 SHRRGFKTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGYKT-AQLSGSVLINSKERNLRRF 220
            .:    |.:::.|:||...|.::|:||||||||:|.:..|.|... ..::|.:|:|.|..:::.:
plant   511 KN----KHLMRCVTGKLSPGRVSAVMGPSGAGKTTFLTALTGKAPGCIMTGMILVNGKVESIQSY 571

  Fly   221 RKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEILETIGLKESVNTLT---- 281
            :|:..::.|||::..||||.|.:..:|..:|..::....||:|||.::|::||:...::|.
plant   572 KKIIGFVPQDDIVHGNLTVEENLWFSARCRLPADLPKPEKVLVVERVIESLGLQHVRDSLVGTVE 636

  Fly   282 -CNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPSA 345
             ..:|||||||:::.||:|..|.::..||||||||||:...|:..||..|..|..|...:||||.
plant   637 KRGISGGQRKRVNVGLEMVMEPSLLILDEPTSGLDSSSSQLLLRALRREALEGVNICMVVHQPSY 701

  Fly   346 RLFEKFDHLYLLAQGQCV-YEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYGDAVPKLVD 409
            .||..||.|.|||:|..: |:|.||.:..|.||||...|...||.||.:::..|       .|..
plant   702 TLFRMFDDLILLAKGGLICYQGPVKKVEEYFSSLGIVVPERVNPPDYYIDILEG-------ILKP 759

  Fly   410 AVKSGACKK------YAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEP 468
            :..||...|      ..|..|.:.:       |::|
plant   760 STSSGVTYKQLPVRWMLHNGYPVPM-------DMLK----------------------------- 788

  Fly   469 SIPVDDPAELKPPKLETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGC 533
                                     |:..|.          ||:.|..:|.|||..|   :|||
plant   789 -------------------------SIEGMA----------SSASGENSAHGGSAHG---SVVG- 814

  Fly   534 MTSLLDSHESVV----------------TLPNKTGFPTSG----------WTQFWILLKRSFRTI 572
                 |...|..                .|.|  .|.:||          :.|:...|.|..:..
plant   815 -----DDGTSFAGEFWQDVKANVEIKKDNLQN--NFSSSGDLSEREVPGVYQQYRYFLGRLGKQR 872

  Fly   573 LRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSNAGCIFFVSLFTTFTAMMPTILTFPTEM 637
            ||:.....:.....::.|..:|.:        :|:....    |.::..|:|.:..::|...|.:
plant   873 LREARTLAVDYLILLLAGICLGTL--------AKVSDET----FGAMGYTYTVIAVSLLCKITAL 925

  Fly   638 SVFVREHLNYW------YSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTSQPMELERVSMFVLI 696
            ..|..:.|:||      .|..|::.||...| .|..:...:..|.::|..:.|......:..|||
plant   926 RSFSLDKLHYWRESRAGMSSLAYFLAKDTVD-HFNTIVKPLVYLSMFYFFNNPRSTVTDNYVVLI 989

  Fly   697 CVLNSL--VAQSLGLLIGAGMNIETGVFLGPVTTIPTILFSGFFVNFDTIPGYLQWVTYVSYVRY 759
            |::..:  :|.:|.:|...|......|.|..|.|:  |..|   .|.:.|   :..::.:.|.|:
plant   990 CLVYCVTGIAYTLAILFEPGPAQLWSVLLPVVLTL--IATS---TNDNKI---VDSISELCYTRW 1046

  Fly   760 GFEGAMVA 767
            ..|..:|:
plant  1047 ALEAFVVS 1054

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	175/678 (26%)
		ABCG_EPDR	142..366	CDD:213180	85/230 (37%)
		ABC2_membrane	564..767	CDD:279410	44/210 (21%)
ABCG28	NP_200882.4	ABCG_EPDR	496..723	CDD:213180	85/230 (37%)
ABCG28	NP_200882.4	3a01204	513..1103	CDD:273361	170/652 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900