DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG23

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_197442.2	Gene:	ABCG23 / 832061	AraportID:	AT5G19410	Length:	633	Species:	Arabidopsis thaliana

Alignment Length:	817	Identity:	186/817 - (22%)
Similarity:	325/817 - (39%)	Gaps:	212/817 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 KSPNRVSDSAATTAPNAVLYTSGNMSLSTLSTGSGNPNPNPNASTNSRQEPVPLLSQLKLTNDLK 90
            |..|.....|:...|:|:..:........|.:.|.:|:...:||::....|:|..::..||
plant     2 KKNNNTHTMASCFHPSAMATSHREEDSIILFSASNSPDEFSSASSSFSSSPLPTPNRYSLT---- 62

  Fly    91 QNSHGSQNNLCNGGLGSNNHALAPKVANNSGGSPNGQKKGTIALSHLPQRPPVDIEFCDISYSVT 155
                                     |.|.|           ..::|.|
plant    63 -------------------------VTNLS-----------YTINHTP----------------- 74

  Fly   156 DSHRRGFKTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAG---YKTAQLSGSVLINSKE-RN 216
                     ||.|||....:.:|.|::||||.|||||:.|::|   :|....|.:||:|::: .:
plant    75 ---------ILNSVSLAAESSKILAVVGPSGTGKSTLLKIISGRVNHKALDPSSAVLMNNRKITD 130

  Fly   217 LRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEILETIGLKESVNTLT 281
            ..:.|:|..::.|||.|:..|||:|.:|.:|...| ::..:..:...||.:|..:||....::..
plant   131 YNQLRRLCGFVPQDDDLLPLLTVKETLMYSAKFSL-RDSTAKEREERVESLLSDLGLVLVQDSFV 194

  Fly   282 -------CNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARG-GRTIVC 338
                   ..:|||:|||:|||:|::.:||::..|||||||||....|::.||.::|:. .||::.
plant   195 GEGDEEDRGVSGGERKRVSIAVEMIRDPPILLLDEPTSGLDSRNSLQVVELLATMAKSKQRTVLF 259

  Fly   339 TIHQPSARLFEKFDHLYLLAQGQCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYGDA 403
            :|||||.|:.:......:|::|..::.|.::.|...::.||::.|...||.::.:|:
plant   260 SIHQPSYRILDYISDYLILSRGSVIHLGSLEHLEDSIAKLGFQIPEQLNPIEFAMEI-------- 316

  Fly   404 VPKLVDAVKSGACKKYAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEP 468
                |:::::
plant   317 ----VESLRT------------------------------------------------------- 322

  Fly   469 SIPVDDPAELKPPKLETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGC 533
                     .||                    |:|              ||..|.|..|
plant   323 ---------FKP--------------------NSV--------------AVVESSSMWP------ 338

  Fly   534 MTSLLDSHESVVTLPNKTGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYY 598
                 :::|:...:..|..|.....|:...|..|..:.|.|.|.|...|....|:.|..:|.:|.
plant   339 -----ENNENDGIISKKEAFRVLDVTEISYLCSRFCKIIYRTKQLFLARTMQAVVAGLGLGSVYT 398

  Fly   599 DVGNEASKIMSNAGCIFFVSLFTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADM 663
            .:..:...:....| :|..||....::.:..:..:..|..|.::|.....|.:.::..|.|||.:
plant   399 RLKRDEEGVAERLG-LFAFSLSFLLSSTVEALPIYLRERRVLMKESSRGSYRISSYMIANTIAFV 462

  Fly   664 PFQIVFSSVYVLVVYYLTSQPMELERVSMFVLICVLNSLVAQSLGLLIGAGMNIETGVFLGPVTT 728
            ||..|.|.::.:.||::......::..|.|||...|..|:|.||.|.:.|    .:..|:...:.
plant   463 PFLFVVSLLFSIPVYWIVGLNPSIQAFSFFVLCVWLIILMASSLVLFLSA----VSPDFISGNSL 523

  Fly   729 IPTI-----LFSGFFVNFDTIPGYLQWVTYVSYVRYGFEGAMVAIY-GMDRAKMQCNQMYCHYRV 787
            |.|:     ||||:|:..:.||....::.|||..||..|..:|..| .|.........|.| ...
plant   524 ICTVLGAFFLFSGYFIPKEKIPKPWMFMYYVSLYRYPLESMVVNEYWSMREECFSSGNMGC-LMT 587

  Fly   788 PKKFLEEMSMDNALFWVDAVALIGIFFALRIIAYFVL 824
            .:..|:|..:|....|::...::..|...||:.:.:|
plant   588 GEDVLKERGLDKDTRWINVGIMLAFFVFYRILCWGIL 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	168/706 (24%)
		ABCG_EPDR	142..366	CDD:213180	76/235 (32%)
		ABC2_membrane	564..767	CDD:279410	56/207 (27%)
ABCG23	NP_197442.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910