DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG22

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_568169.1	Gene:	ABCG22 / 830541	AraportID:	AT5G06530	Length:	751	Species:	Arabidopsis thaliana

Alignment Length:	862	Identity:	236/862 - (27%)
Similarity:	393/862 - (45%)	Gaps:	207/862 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 KSPNRVSDS--AATTAPNAVLYTSGNMSLSTLSTG---SGNPNPNPNASTNSRQEPVPLLSQLKL 85
            :||:...|:  ...|||.||   .|..:||..|:.   ..:|..:..|.|:.|:.   ..:||||
plant    29 RSPHGSMDANGVPATAPAAV---GGGGTLSRKSSRRLMGMSPGRSSGAGTHIRKS---RSAQLKL 87

  Fly    86 TNDLKQNSHGSQ-NNLCNGGLGSN----NHALAPKVANNS--------------GG--SPNGQKK 129
              :|::.|.|:. :...:..||.:    ..|:.|:..::|              .|  .|..|.:
plant    88 --ELEEVSSGAALSRASSASLGLSFSFTGFAMPPEEISDSKPFSDDEMIPEDIEAGKKKPKFQAE 150

  Fly   130 GTIALSHLPQRPPVDIEFCDISYSV-----TDSHRRGFKTILKSVSGKFRNGEITAIMGPSGAGK 189
            .|:         |:.::|.|::|.|     |.|..   |.||..:||....||:.|:|||||:||
plant   151 PTL---------PIFLKFRDVTYKVVIKKLTSSVE---KEILTGISGSVNPGEVLALMGPSGSGK 203

  Fly   190 STLMNILAGYKTAQLS--GSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLG 252
            :||:::||| :.:|.|  |||..|.|..:.....|:. ::.|||||..:|||:|.:..||.|:|.
plant   204 TTLLSLLAG-RISQSSTGGSVTYNDKPYSKYLKSKIG-FVTQDDVLFPHLTVKETLTYAARLRLP 266

  Fly   253 KNMISYAKVVVVEEILETIGLKESVNTL-----TCNLSGGQRKRLSIALELVNNPPVMFFDEPTS 312
            |.:....|.....::::.:||:...:|:     ...:|||:|||:||..|::.||.::..|||||
plant   267 KTLTREQKKQRALDVIQELGLERCQDTMIGGAFVRGVSGGERKRVSIGNEIIINPSLLLLDEPTS 331

  Fly   313 GLDSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQGQCVYEGRVKGLVPYLSS 377
            ||||:|..:.|.:|..:|..|:|::.||||||:|||.:||.|.||.:|..:|.|:....:.|.||
plant   332 GLDSTTALRTILMLHDIAEAGKTVITTIHQPSSRLFHRFDKLILLGRGSLLYFGKSSEALDYFSS 396

  Fly   378 LGYECPSYHNPADYVLEVASGEYGD-AVP-KLVDAVKSG--------------ACKKYAHKDYVL 426
            :|.......|||:::|::|:|...| :|| :|.|.|:.|              |..:|..:.|..
plant   397 IGCSPLIAMNPAEFLLDLANGNINDISVPSELDDRVQVGNSGRETQTGKPSPAAVHEYLVEAYET 461

  Fly   427 TLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQNS 491
            .:|                         |.||..|    |:| :|:|:.|:.|..:|:.|
plant   462 RVA-------------------------EQEKKKL----LDP-VPLDEEAKAKSTRLKRQ----- 491

  Fly   492 DCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTS 556
                                                                         :.|.
plant   492 -------------------------------------------------------------WGTC 495

  Fly   557 GWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYY--DVGNEASKIMSNAGCIFFVSL 619
            .|.|:.||..|..:. .|.:..:.:|:...:....|:|::::  |:..... :...||.:||:::
plant   496 WWEQYCILFCRGLKE-RRHEYFSWLRVTQVLSTAVILGLLWWQSDIRTPMG-LQDQAGLLFFIAV 558

  Fly   620 FTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTS-- 682
            |..|..:...|..||.|.::..:|.....|.|.|::.|:|.:|:|...:..|:::||||::|.
plant   559 FWGFFPVFTAIFAFPQERAMLNKERAADMYRLSAYFLARTTSDLPLDFILPSLFLLVVYFMTGLR 623

  Fly   683 ---QPMELERVSMFVLICVLNSLVAQSLGLLIGA-GMNIETGVFLGPVTTIPTILFSGFFVNFDT 743
               .|..|..:::|  :|:   :.||.|||.||| .|:::....|..||.:..:|..||||.  .
plant   624 ISPYPFFLSMLTVF--LCI---IAAQGLGLAIGAILMDLKKATTLASVTVMTFMLAGGFFVK--K 681

  Fly   744 IPGYLQWVTYVSYVRYGFEGAMVAIYGMDRAKMQCNQMYCHYRVPKKFLEEMSMDNALFWVDAVA 808
            :|.::.|:.|:|:..:.:             |:.....|..:.|.   :..|.:||.|  .:..|
plant   682 VPVFISWIRYLSFNYHTY-------------KLLLKVQYQDFAVS---INGMRIDNGL--TEVAA 728

  Fly   809 LIGIFFALRIIAYFVLR 825
            |:.:.|..|::||..||
plant   729 LVVMIFGYRLLAYLSLR 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	202/723 (28%)
		ABCG_EPDR	142..366	CDD:213180	95/235 (40%)
		ABC2_membrane	564..767	CDD:279410	56/210 (27%)
ABCG22	NP_568169.1	PLN03211	112..748	CDD:215634	211/771 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	85	1.000	Domainoid score	I2816
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.710