DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG19

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_191073.1	Gene:	ABCG19 / 824679	AraportID:	AT3G55130	Length:	725	Species:	Arabidopsis thaliana

Alignment Length:	769	Identity:	199/769 - (25%)
Similarity:	336/769 - (43%)	Gaps:	160/769 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 GGSPNGQKKG-----TIALSHLPQRP-PVDIEFCDISYSVTDSHRRGF------KTILKSVSGKF 173
            |.|.:|.|..     .|.:..|..:| |..:.|.::.|.||...|.||      ||:|..|||:.
plant    43 GDSGDGVKSDDPAHHIIDVEALYVKPVPYVLNFNNLQYDVTLRRRFGFSRQNGVKTLLDDVSGEA 107

  Fly   174 RNGEITAIMGPSGAGKSTLMNILAGYKTAQ--LSGSVLIN-SKERNLRRFRKLSCYIMQDDVLIA 235
            .:|:|.|::|.||||||||::.||| :.|:  |.|||.:| .|....|..:.:|.|:||||:|..
plant   108 SDGDILAVLGASGAGKSTLIDALAG-RVAEGSLRGSVTLNGEKVLQSRLLKVISAYVMQDDLLFP 171

  Fly   236 NLTVREAMMVAANLKLGKNMISYAKVVVVEEILETIGLKESVNTLTCN-----LSGGQRKRLSIA 295
            .|||:|.:|.|:..:|.:::....|:..||.:::.:||:.:.||:..:     :|||:|:|:||.
plant   172 MLTVKETLMFASEFRLPRSLSKSKKMERVEALIDQLGLRNAANTVIGDEGHRGVSGGERRRVSIG 236

  Fly   296 LELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQG 360
            ::::::|.|:|.|||||||||:..|.::.:|:.:|:.|..::.:|||||||:.|..|.|.:|::|
plant   237 IDIIHDPIVLFLDEPTSGLDSTNAFMVVQVLKRIAQSGSIVIMSIHQPSARIVELLDRLIILSRG 301

  Fly   361 QCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYGDAVPKLVDAVKSGACKKYAHKDYV 425
            :.|:.|....|..:.|..|...|...|.:::.|               |.|:.
plant   302 KSVFNGSPASLPGFFSDFGRPIPEKENISEFAL---------------DLVRE------------ 339

  Fly   426 LTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQN 490
                        ::||..|.:   |::...:                             :..||
plant   340 ------------LEGSNEGTK---ALVDFNE-----------------------------KWQQN 360

  Fly   491 SDCSVVNMP-TNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFP 554
            ....:.:.| ||.:|...|.|    .:.|:..|.|.| ..|.|...|...|.|:|.:..|.:.|.
plant   361 KISLIQSAPQTNKLDQDRSLS----LKEAINASVSRG-KLVSGSSRSNPTSMETVSSYANPSLFE 420

  Fly   555 TSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSNAGCIFFVSL 619
            |      :||.||..:..:|...|...|:.:.::.|.::..:|:.:.:.............|| :
plant   421 T------FILAKRYMKNWIRMPELVGTRIATVMVTGCLLATVYWKLDHTPRGAQERLTLFAFV-V 478

  Fly   620 FTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTSQP 684
            .|.|...:..:..|..|..:|:||..:..|...::..:.::..:|..:..|.|:..:.::.....
plant   479 PTMFYCCLDNVPVFIQERYIFLRETTHNAYRTSSYVISHSLVSLPQLLAPSLVFSAITFWTVGLS 543

  Fly   685 MELERVSMFVLICVL--------NSLVAQSLGLLIGAGMNIETGVFLGPVTTIPTILFSGFFVNF 741
            ..||.   ||..|:|        :|:|.    .:.|...||.....:........:|.|||:||.
plant   544 GGLEG---FVFYCLLIYASFWSGSSVVT----FISGVVPNIMLCYMVSITYLAYCLLLSGFYVNR 601

  Fly   742 DTIPGYLQWVTYVSYVRYGFEGAMV-------------------AIYG--MDRAKM--------- 776
            |.||.|..|..|:|.::|.:|..::                   .:.|  .|..|:
plant   602 DRIPFYWTWFHYISILKYPYEAVLINEFDDPSRCFVRGVQVFDSTLLGGVSDSGKVKLLETLSKS 666

  Fly   777 ---QCNQMYCHYRVPKKFLEEMSMDNALFWVDAVALI---GIFFALRIIAYFVL 824
               :..:..| .|.....|.:..:.....| |.:.:.   |:||  ||:.||.|
plant   667 LRTKITESTC-LRTGSDLLAQQGITQLSKW-DCLWITFASGLFF--RILFYFAL 716

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	194/748 (26%)
		ABCG_EPDR	142..366	CDD:213180	94/237 (40%)
		ABC2_membrane	564..767	CDD:279410	47/229 (21%)
ABCG19	NP_191073.1	P-loop_NTPase	89..307	CDD:304359	88/218 (40%)
		3a01204	90..724	CDD:273361	185/722 (26%)
		ABC2_membrane	424..627	CDD:279410	47/210 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810