DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG17

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_001319754.1	Gene:	ABCG17 / 824676	AraportID:	AT3G55100	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	750	Identity:	186/750 - (24%)
Similarity:	304/750 - (40%)	Gaps:	169/750 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 SHLPQRPPVDIEFCDISYSVTDSHRRG---------FKTILKSVSGKFRNGEITAIMGPSGAGKS 190
            |.:|..|.| :.|.|::|:||...|.|         .||:|..::|:.:.|||.||:|.||||||
plant    13 SEIPPIPFV-LAFNDLTYNVTLQQRFGLRFGHSPAKIKTLLNGITGEAKEGEILAILGASGAGKS 76

  Fly   191 TLMNILAG-YKTAQLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLGKN 254
            ||::.||| .....|.|:|.:|.:....|..|.:|.|:||:|:|...|||.|.:|.||..:|.::
plant    77 TLIDALAGQIAEGSLKGTVTLNGEALQSRLLRVISAYVMQEDLLFPMLTVEETLMFAAEFRLPRS 141

  Fly   255 MISYAKVVVVEEILETIGLKESVNTLTCN-----LSGGQRKRLSIALELVNNPPVMFFDEPTSGL 314
            :....|...||.:::.:||....||:..:     :|||:|:|:||..:::::|.|:|.|||||||
plant   142 LSKSKKRNRVETLIDQLGLTTVKNTVIGDEGHRGVSGGERRRVSIGTDIIHDPIVLFLDEPTSGL 206

  Fly   315 DSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQGQCVYEGRVKGLVPYLSSLG 379
            ||::.|.::.:|:.:||.|..::.:|||||.|:.|..|.:.:|:.||.|:......|..:.|..|
plant   207 DSTSAFMVVQVLKKIARSGSIVIMSIHQPSGRIMEFLDRVIVLSSGQIVFSDSPATLPLFFSEFG 271

  Fly   380 YECPSYHNPADYVLEVASGEYGDAVPKLVDAVKSGACKKYAHKDYVLTLAQKGCNNDIIKGSGSG 444
            ...|...|.|::.|::.                         ||              ::||..|
plant   272 SPIPEKENIAEFTLDLI-------------------------KD--------------LEGSPEG 297

  Fly   445 AENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQNSDCSVVNMPTNAVDDSCSF 509
            ....                       |:.....:..||...|..:.:.|.:....||
plant   298 TRGL-----------------------VEFNRNWQHRKLRVSQEPHHNSSSLGEAINA------- 332

  Fly   510 SSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTSGWTQFWILLKRSFRTILR 574
            |.|:|  ..|..|....||.|                        ...|.:..||.||......|
plant   333 SISRG--KLVSTSYRSIPSYV------------------------NPWWVETVILAKRYMINWTR 371

  Fly   575 DKMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSNAGCIFFVSLFTTFTAMMPTILTFPTEMSV 639
            ...|...|:|..::.|.::..:|:.|.:....:..... .|..::.|.|.:....:..|..|..:
plant   372 TPELIGTRVFIVMMTGFLLATVYWKVDDSPRGVQERLS-FFSFAMATMFYSCADGLPAFIQERYI 435

  Fly   640 FVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTSQPMELERVSMFVLICVLN---- 700
            |:||..:..|...::..:.::..:|.....|..:....::.......|.....:::|...:
plant   436 FLRETAHNAYRRSSYVISHSLVTLPHLFALSIGFAATTFWFVGLNGGLAGFIYYLMIIFASFWSG 500

  Fly   701 -SLVAQSLGLLIGAGMNIETGVFLGPVTTIP----TILFSGFFVNFDTIPGYLQWVTYVSYVRYG 760
             |.|....|::        ..|.:..:.|..    .:|||||:||.|.|..|..|:.|:|.::|.
plant   501 CSFVTFVSGVI--------PNVMMSYMVTFGYLSYCLLFSGFYVNRDRIHLYWIWIHYISLLKYP 557

  Fly   761 FEGAMVAIY-GMDRAKMQCNQMY-------CHYRVPKKFLEEMS--------------------- 796
            :|..:...: ...|..::.||::       .......|.||.||
plant   558 YEAVLHNEFDDPSRCFVRGNQVFDNTIMEGVSETTKAKLLETMSGYLGMELTESTCLTTGSDLLK 622

  Fly   797 ------MDN-ALFWVDAVALIGIFFALRIIAYFVL 824
                  :|. ...||  ....|.||  ||:.||.|
plant   623 QHGIEQLDKWGCLWV--TLAWGFFF--RILFYFSL 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	184/747 (25%)
		ABCG_EPDR	142..366	CDD:213180	92/238 (39%)
		ABC2_membrane	564..767	CDD:279410	43/211 (20%)
ABCG17	NP_001319754.1	3a01204	18..661	CDD:273361	183/744 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810