DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG20

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_190919.1	Gene:	ABCG20 / 824519	AraportID:	AT3G53510	Length:	739	Species:	Arabidopsis thaliana

Alignment Length:	782	Identity:	186/782 - (23%)
Similarity:	322/782 - (41%)	Gaps:	177/782 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 NHALAPKVANNSGGSPNGQKKGTIALSHLPQRPPVDIEFCDISYSVT------------------ 155
            :.|:...||:|...|        :..|.:|...|..:.|.|::|||.
plant    60 SRAMDIAVASNFWSS--------VPSSRVPSSSPFVLSFKDLTYSVKIKKKFKPFPCCGNSPFDG 116

  Fly   156 DSHRRGFKTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAG-YKTAQLSGSVLINSKERNLRR 219
            :......|.:|..:||:.|.||:.|::|.||:|||||::.||. .....|.|.:.:|.:......
plant   117 NDMEMNTKVLLNGISGEAREGEMMAVLGASGSGKSTLIDALANRISKESLRGDITLNGEVLESSL 181

  Fly   220 FRKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEILETIGLKESVNTLTCN- 283
            .:.:|.|:||||:|...|||.|.:|.:|..:|..::....|...|:.:::.:||:.:..|:..:
plant   182 HKVISAYVMQDDLLFPMLTVEETLMFSAEFRLPSSLSKKKKKARVQALIDQLGLRNAAKTVIGDE 246

  Fly   284 ----LSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPS 344
                :|||:|:|:||..:::::|.::|.|||||||||::.:.::.:|:.:|:.|..::.:|||||
plant   247 GHRGVSGGERRRVSIGTDIIHDPIILFLDEPTSGLDSTSAYMVVKVLQRIAQSGSIVIMSIHQPS 311

  Fly   345 ARLFEKFDHLYLLAQGQCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYGDAVPKLVD 409
            .|:....|.|..|::|..||.|....|..:.|..|:..|...|..::.|        |.:.:|.|
plant   312 YRILGLLDKLIFLSRGNTVYSGSPTHLPQFFSEFGHPIPENENKPEFAL--------DLIRELED 368

  Fly   410 AVKSGACKKYAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDD 474
            :.:........||.:
plant   369 SPEGTKSLVEFHKQW-------------------------------------------------- 383

  Fly   475 PAELKPPKLETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLD 539
                :..:..:|..:|::.|        :.|:.|.|.|:|  ..|.|:            |:|..
plant   384 ----RAKQTSSQSRRNTNVS--------LKDAISASISRG--KLVSGA------------TNLRS 422

  Fly   540 SHESVVTLPNKTGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEA 604
            |.::         |....||:..::.|||.....|...|..:||.:.::.|.|:..|::.:.|..
plant   423 SFQT---------FANPFWTEMLVIGKRSILNSRRQPELFGIRLGAVLVTGMILATIFWKLDNSP 478

  Fly   605 SKIMSNAGCIFFVSLFTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVF 669
            ..|....| .|..::.|||......|..|..|..:|:||.....|...::..|.||..:|..|:.
plant   479 RGIQERLG-FFAFAMSTTFYTCAEAIPVFLQERYIFMRETAYNAYRRSSYVLAHTIISIPALIIL 542

  Fly   670 SSVYVLVVYYLTSQPMELERVSMFVLICVLNSLVAQSLGLLIGAGMNIETGVFLGPVTTIPT--- 731
            |:.:....:.........|.. :|....:|.:..|.|..:...:|  :.:.|.:|....:..
plant   543 SAAFAASTFSAVGLAGGSEGF-LFFFFTILTAFWAGSSFVTFLSG--VVSHVMIGFTVVVAILAY 604

  Fly   732 -ILFSGFFVNFDTIPGYLQWVTYVSYVRYGFEG-------------------------------- 763
             :||||||::.|.||.|..|..|:|.|:|.:||
plant   605 FLLFSGFFISRDRIPLYWIWFHYLSLVKYPYEGVLQNEFEDPTKCFVRGIQMFDNSPLGQVPTAV 669

  Fly   764 ------AMVAIYGMDRAKMQCNQMYCHYRVPKKFLEEMSMDNALFWVDAVALIGIFFALRIIAYF 822
                  :|..:.|::.....|....... :.::.:.|:|..|.| |: .||. |.||  |::.||
plant   670 KISLLKSMSGVLGINVTAETCVTTGIDI-LKQQGITEISKWNCL-WI-TVAW-GFFF--RVLFYF 728

  Fly   823 VL 824
            .|
plant   729 TL 730

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	180/754 (24%)
		ABCG_EPDR	142..366	CDD:213180	79/247 (32%)
		ABC2_membrane	564..767	CDD:279410	56/244 (23%)
ABCG20	NP_190919.1	P-loop_NTPase	119..333	CDD:304359	73/213 (34%)
		3a01204	120..738	CDD:273361	173/714 (24%)
		ABC2_membrane	438..641	CDD:279410	55/206 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810