DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG37

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_190916.1	Gene:	ABCG37 / 824516	AraportID:	AT3G53480	Length:	1450	Species:	Arabidopsis thaliana

Alignment Length:	721	Identity:	182/721 - (25%)
Similarity:	305/721 - (42%)	Gaps:	164/721 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 PVDIEFCDISYSV---TDSHRRGFK----TILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGY 199
            |:.:.|.|::|.|   .:...:|:.    .:|..::|.||.|.:||:||.|||||:||:::|||.
plant   847 PLTVTFQDLNYFVDMPVEMRDQGYDQKKLQLLSDITGAFRPGILTALMGVSGAGKTTLLDVLAGR 911

  Fly   200 KTA-QLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVV 263
            ||: .:.|.:.|:...:....|.::|.|..|.|:...|:||.|:::.:|.|:|...:.:..|...
plant   912 KTSGYIEGDIRISGFPKVQETFARVSGYCEQTDIHSPNITVEESVIYSAWLRLAPEIDATTKTKF 976

  Fly   264 VEEILETIGLKESVNTL-----TCNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLI 323
            |:::||||.|.|..::|     ...||..|||||:||:|||.||.::|.||||:|||:.....::
plant   977 VKQVLETIELDEIKDSLVGVTGVSGLSTEQRKRLTIAVELVANPSIIFMDEPTTGLDARAAAIVM 1041

  Fly   324 SLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQ-GQCVYEGRV----KGLVPYLSSLGYECP 383
            ..::::|..||||||||||||..:||.||.|.||.: |:.:|.|.:    :.::.|..|:. |.|
plant  1042 RAVKNVADTGRTIVCTIHQPSIDIFEAFDELVLLKRGGRMIYTGPLGQHSRHIIEYFESVP-EIP 1105

  Fly   384 SY---HNPADYVLEVASG----EYGDAVPKLVDAVK----SGACKKYAHKDYVLTLAQKGCNNDI 437
            ..   ||||.::|:|:|.    |.|      ||..|    |...|:               |:::
plant  1106 KIKDNHNPATWMLDVSSQSVEIELG------VDFAKIYHDSALYKR---------------NSEL 1149

  Fly   438 IKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQNSDCSVVNMPTNA 502
            :|                                          :|....|.:||
plant  1150 VK------------------------------------------QLSQPDSGSSD---------- 1162

  Fly   503 VDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTSGWTQFWILLKR 567
                                                        :..|..|..|.|.||..:|.:
plant  1163 --------------------------------------------IQFKRTFAQSWWGQFKSILWK 1183

  Fly   568 SFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVG---NEASKIMSNAGCIFFVSLFTTFTAMMPT 629
            ...:..|......||:...::...|.|.:::..|   :....:.:..|.|:.:.||.........
plant  1184 MNLSYWRSPSYNLMRMMHTLVSSLIFGALFWKQGQNLDTQQSMFTVFGAIYGLVLFLGINNCASA 1248

  Fly   630 ILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVY-----YLTSQPMELER 689
            :..|.||.:|..||.....||..|:...:.:.::|:..:.::.:|:|.|     |.::..:....
plant  1249 LQYFETERNVMYRERFAGMYSATAYALGQVVTEIPYIFIQAAEFVIVTYPMIGFYPSAYKVFWSL 1313

  Fly   690 VSMFVLICVLNSLVAQSLGLLIGAGMNIETGVFLGPVTTIPTILFSGFFVNFDTIPGYLQWVTYV 754
            .|||..:...|.|..    .|:....|......|..:..:...|||||.:....:||:..|:.|:
plant  1314 YSMFCSLLTFNYLAM----FLVSITPNFMVAAILQSLFYVGFNLFSGFLIPQTQVPGWWIWLYYL 1374

  Fly   755 SYVRYGFEGAMVAIYGMDRAKMQCNQMYCHYRVPKKFLEE-MSMDNALFWVDAVALIGIFFAL-R 817
            :...:...|.:.:.||....::   .::.......:||:: ....:.|..|.||..|....|| .
plant  1375 TPTSWTLNGFISSQYGDIHEEI---NVFGQSTTVARFLKDYFGFHHDLLAVTAVVQIAFPIALAS 1436

  Fly   818 IIAYFV 823
            :.|:||
plant  1437 MFAFFV 1442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	182/721 (25%)
		ABCG_EPDR	142..366	CDD:213180	94/237 (40%)
		ABC2_membrane	564..767	CDD:279410	43/210 (20%)
ABCG37	NP_190916.1	PLN03140	54..1450	CDD:215599	182/721 (25%)
		ABC_trans_N	89..167	CDD:291196
		ABCG_PDR_domain1	186..429	CDD:213200
		ABC2_membrane	530..735	CDD:279410
		PDR_assoc	742..804	CDD:285559
		ABCG_PDR_domain2	847..1085	CDD:213199	94/237 (40%)
		ABC2_membrane	1180..1387	CDD:279410	43/210 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324553at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920