DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG21

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_001189973.1	Gene:	ABCG21 / 822149	AraportID:	AT3G25620	Length:	672	Species:	Arabidopsis thaliana

Alignment Length:	755	Identity:	210/755 - (27%)
Similarity:	358/755 - (47%)	Gaps:	137/755 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 SNNHALAPKVAN---------------NSGGSPNGQKKGTIALSHLPQRPPVDIEFCDISYSVTD 156
            :|.|..:|...|               |....|:.|.:.:..|..  ...|:.::|.:::||:..
plant    17 ANRHETSPVQENRFSSPSHVNPCLDDDNDHDGPSHQSRQSSVLRQ--SLRPIILKFEELTYSIKS 79

  Fly   157 SHRRGF-----------KTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGYKTAQLSGSVLI 210
            ...:|.           :.:||.|||..:.||:.|::||||:||:||:..|||....:|||:|..
plant    80 QTGKGSYWFGSQEPKPNRLVLKCVSGIVKPGELLAMLGPSGSGKTTLVTALAGRLQGKLSGTVSY 144

  Fly   211 NSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEILETIGLKE 275
            |.:.......||.. ::.|||||..:|||.|.:...|.|:|.|.:....|:..||.::..:||..
plant   145 NGEPFTSSVKRKTG-FVTQDDVLYPHLTVMETLTYTALLRLPKELTRKEKLEQVEMVVSDLGLTR 208

  Fly   276 SVNT-----LTCNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGRT 335
            ..|:     |...:|||:|||:||..|::.||.::..|||||||||:|..::::.||||||||||
plant   209 CCNSVIGGGLIRGISGGERKRVSIGQEMLVNPSLLLLDEPTSGLDSTTAARIVATLRSLARGGRT 273

  Fly   336 IVCTIHQPSARLFEKFDHLYLLAQGQCVYEGRVKGLVPYLSSLGYECP--SYHNPADYVLEVASG 398
            :|.||||||:||:..||.:.:|::|..:|.|....::.|..|:||: |  |:.||||:||::|:|
plant   274 VVTTIHQPSSRLYRMFDKVLVLSEGCPIYSGDSGRVMEYFGSIGYQ-PGSSFVNPADFVLDLANG 337

  Fly   399 EYGDAVPKLVDAVKSGACKKYAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLED 463
            ...|.             |:|                |.|:.:|       .:..||      |.
plant   338 ITSDT-------------KQY----------------DQIETNG-------RLDRLE------EQ 360

  Fly   464 RQLEPSIPVDDPAELKPP-KLETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGP 527
            ..::.|:.......|.|| |.|..::...|.:...:...|:.:.
plant   361 NSVKQSLISSYKKNLYPPLKEEVSRTFPQDQTNARLRKKAITNR--------------------- 404

  Fly   528 SAVVGCMTSLLDSHESVVTLPNKTGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAI 592
                                     :|||.|.||.:||||..:....:. .:.:|:|..:.|..:
plant   405 -------------------------WPTSWWMQFSVLLKRGLKERSHES-FSGLRIFMVMSVSLL 443

  Fly   593 IGMIYYDVGNEASKIMSNAGCIFFVSLFTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFA 657
            .|::::.  :..:.:....|.:||.|:|..|..:...|.|||.|..:.::|..:..|.|.::|.|
plant   444 SGLLWWH--SRVAHLQDQVGLLFFFSIFWGFFPLFNAIFTFPQERPMLIKERSSGIYRLSSYYIA 506

  Fly   658 KTIADMPFQIVFSSVYVLVVYYLTSQPMELERVSMFVLICVLNSLVAQSLGLLIGA-GMNIETGV 721
            :|:.|:|.:::..:::|.:.|::......|....|.::|.:.|.||||.:||.:|| .|:.:...
plant   507 RTVGDLPMELILPTIFVTITYWMGGLKPSLTTFIMTLMIVLYNVLVAQGVGLALGAILMDAKKAA 571

  Fly   722 FLGPVTTIPTILFSGFFVNFDTIPGYLQWVTYVSYVRYGFEGAMVAIYGMDRAKMQCNQ-MYCHY 785
            .|..|..:..:|..|:::..  |||::.|:.|||:..|.::..:...|..|.. .:|.. ::|..
plant   572 TLSSVLMLVFLLAGGYYIQH--IPGFIAWLKYVSFSHYCYKLLVGVQYTWDEV-YECGSGLHCSV 633

  Fly   786 RVPKKFLEEMSMDNALFWVDAVALIGIFFALRIIAYFVLR 825
             :..:.::.:.:.| :.| |.:||..:....|::||..||
plant   634 -MDYEGIKNLRIGN-MMW-DVLALAVMLLLYRVLAYLALR 670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	200/708 (28%)
		ABCG_EPDR	142..366	CDD:213180	96/239 (40%)
		ABC2_membrane	564..767	CDD:279410	54/203 (27%)
ABCG21	NP_001189973.1	PLN03211	43..670	CDD:215634	204/727 (28%)
		P-loop_NTPase	89..304	CDD:304359	91/215 (42%)
		ABC2_membrane	416..615	CDD:279410	54/203 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	85	1.000	Domainoid score	I2816
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H75179
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.710