DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG26

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_187928.2	Gene:	ABCG26 / 820512	AraportID:	AT3G13220	Length:	685	Species:	Arabidopsis thaliana

Alignment Length:	722	Identity:	185/722 - (25%)
Similarity:	329/722 - (45%)	Gaps:	138/722 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 PVDIEFCDISYSVTDSHRR---------------------GFKTILKSVSGKFRNGEITAIMGPS 185
            |:.::|.|:.|.|.:||..                     |:|.|||.::|....|||.|:||||
plant    62 PIFLKFEDVEYKVRNSHASSANLVKTMVSKVVTHTNPDPDGYKHILKGITGSTGPGEILALMGPS 126

  Fly   186 GAGKSTLMNILAGYKTAQLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLK 250
            |:||:||:.|:.|..|..:.|.:..|....:....|::. ::.|||||:..|||.|.:..||.|:
plant   127 GSGKTTLLKIMGGRLTDNVKGKLTYNDIPYSPSVKRRIG-FVTQDDVLLPQLTVEETLAFAAFLR 190

  Fly   251 LGKNMISYAKVVVVEEILETIGLKESVNT-----LTCNLSGGQRKRLSIALELVNNPPVMFFDEP 310
            |..:|....|...:|.|::.:||:....|     ....:|||:|||.|||.|::.:|.::..|||
plant   191 LPSSMSKEQKYAKIEMIIKELGLERCRRTRVGGGFVKGISGGERKRASIAYEILVDPSLLLLDEP 255

  Fly   311 TSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQGQCVYEGRVKGLVPYL 375
            ||||||::..:|:.:|:.:|:.|||::.||||||:|:|..||.|.|:::|...:.|:.:..:.|.
plant   256 TSGLDSTSATKLLHILQGVAKAGRTVITTIHQPSSRMFHMFDKLLLISEGHPAFYGKARESMEYF 320

  Fly   376 SSLGYECPSYHNPADYVLEVASGEYGD-AVPKLVDAVKSGACKKYAHKDYVLTLAQKGCNNDIIK 439
            |||........|||:::|::|:|:..| ::|..:.|.|:               ||......::|
plant   321 SSLRILPEIAMNPAEFLLDLATGQVSDISLPDELLAAKT---------------AQPDSEEVLLK 370

  Fly   440 GSGSGAENAMAILTLEDEKPPLEDR---QLEPSIPVDDPAELKPPKLETQQSQNSDCSVVNMPTN 501
                                .|:.|   .|||....::....|.|:
plant   371 --------------------YLKQRYKTDLEPKEKEENHRNRKAPE------------------- 396

  Fly   502 AVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTSGWTQFWILLK 566
                                                    ...:.:..|..:..|.|.||.||.:
plant   397 ----------------------------------------HLQIAIQVKKDWTLSWWDQFLILSR 421

  Fly   567 RSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEA-SKIMSNAGCIFFVSLFTTFTAMMPTI 630
            |:||...|| ....:||...:.|..::|::::....:. :.:....|.:|::.:|.|.:::...:
plant   422 RTFRERRRD-YFDKLRLVQSLGVAVVLGLLWWKSKTDTEAHLRDQVGLMFYICIFWTSSSLFGAV 485

  Fly   631 LTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTSQPMELERVSMFVL 695
            ..||.|....|:|.....|.|..:|...|:.||...:::.:.::::||::......:......||
plant   486 YVFPFEKIYLVKERKAEMYRLSVYYVCSTLCDMVAHVLYPTFFMIIVYFMAEFNRNIPCFLFTVL 550

  Fly   696 ICVLNSLVAQSLGLLIGAG-MNIETGVFLGPVTTIPTILFSGFFVNFDTIPGYLQWVTYVSYVRY 759
            ..:|.::.:|..|..:||. ::|:....:..:..:..:|..|::|..  ||.::||:.|:|::.|
plant   551 TILLIAITSQGAGEFLGASVLSIKRAGMIASLVLMLFLLTGGYYVQH--IPKFMQWLKYLSFMHY 613

  Fly   760 GFEGAMVAIYGMDRAKMQC-NQMYCHYRVPKKFLEEMSMDNAL--FWVDAVALIGIFFALRIIAY 821
            ||...:...|..|:. .:| ::..|.........:.::::..|  .||    |:.:.|..|:.||
plant   614 GFRLLLKVQYSADQL-FECGSKGGCRTLQSSSSFDTINLNGGLQELWV----LLAMAFGYRLCAY 673

  Fly   822 FVLRWKL 828
            |.||.|:
plant   674 FCLRKKI 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	182/717 (25%)
		ABCG_EPDR	142..366	CDD:213180	91/249 (37%)
		ABC2_membrane	564..767	CDD:279410	47/204 (23%)
ABCG26	NP_187928.2	PLN03211	62..678	CDD:215634	183/718 (25%)
		ABCG_EPDR	93..311	CDD:213180	84/218 (39%)
		ABC2_membrane	435..621	CDD:279410	41/187 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	85	1.000	Domainoid score	I2816
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.710