DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and NAP12

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_001323430.1	Gene:	NAP12 / 818275	AraportID:	AT2G37010	Length:	1082	Species:	Arabidopsis thaliana

Alignment Length:	873	Identity:	203/873 - (23%)
Similarity:	341/873 - (39%)	Gaps:	227/873 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SAATTAPNAVLYTSGNMSLSTLSTGSGNPNPNP----NASTNSRQEPVPLLSQLKLTNDLKQNSH 94
            :|...|.|..:..|..:|.:.....|...:..|    ..|.:.::||..|...:|...:...|:.
plant   349 TAKGVAKNQKMGLSAQLSQTFSRMKSARKDATPVKASGKSKDKKKEPSNLTKMMKSMEENPSNNE 413

  Fly    95 GSQNNLCNGGLGS--NNHALAPK-----------------VANNSGGSPNGQK---KGTIAL--- 134
            |     .|.|.||  .....|||                 :........|.:.   .|.|::
plant   414 G-----FNVGTGSKPGKKPQAPKGKQLHTQSQIFKYAYGQIEKEKAMEQNNKNLTFSGVISMATD 473

  Fly   135 SHLPQRPPVDIEFCDISYSVTDSHRRGFKTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGY 199
            :.:..||.:::.|.|::.::...|    |.||:||:||...|.::|:||||||||:|.::.|||.
plant   474 TEMRTRPVIEVAFKDLTLTLKGKH----KHILRSVTGKIMPGRVSAVMGPSGAGKTTFLSALAGK 534

  Fly   200 KT-AQLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVV 263
            .| ...:|.:|||.:..::..::|::.::.||||:..||||.|.:..:|..:|...|....||::
plant   535 ATGCTRTGLILINGRNDSINSYKKITGFVPQDDVVHGNLTVEENLRFSARCRLSAYMSKADKVLI 599

  Fly   264 VEEILETIGLKESVNTLT-----CNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLI 323
            :|.::|::||:...::|.     ..:|||||||:::.:|:|..|.::..||||:||||::...|:
plant   600 IERVIESLGLQHVRDSLVGTIEKRGISGGQRKRVNVGVEMVMEPSLLILDEPTTGLDSASSQLLL 664

  Fly   324 SLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQ-GQCVYEGRVKGLVPYLSSLGYECPSYHN 387
            ..||..|..|..|...:||||..:::.||.:.:||: |..||.|.||.:..|.:.:|...|...|
plant   665 RALRREALEGVNICMVVHQPSYTMYKMFDDMIILAKGGLTVYHGSVKKIEEYFADIGITVPDRVN 729

  Fly   388 PADYVLEVASG---EYGDAVPKLVDAVKSGACKKYAHKDYVLTLAQKGCNNDIIK--------GS 441
            |.|:.:::..|   ..||.      .::....:...|..|.:.       :|::|        .:
plant   730 PPDHYIDILEGIVKPDGDI------TIEQLPVRWMLHNGYPVP-------HDMLKFCDGLPSSST 781

  Fly   442 GSGAE----NAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQNSDCSVVNMPTNA 502
            ||..|    |:.:....:|.|..:|                    :...|.|:
plant   782 GSAQEDSTHNSFSNDLWQDVKTNVE--------------------ITKDQLQH------------ 814

  Fly   503 VDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTSGWTQFWILLKR 567
                 ::|:|....|.|                                 .||.| .|:...:.|
plant   815 -----NYSNSHDNSNRV---------------------------------TPTVG-RQYRYFVGR 840

  Fly   568 SFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSNAGCIFFVSLFTTFTAMMPTILT 632
            ..:..||:..|..:.....::.||.:|.: ..|.:|....:.....|..|||....:|:..
plant   841 VGKQRLREARLQALDFLILLVAGACLGTL-AKVNDETIDTLGYTYTIIAVSLLCKISALRS---- 900

  Fly   633 FPTEMSVFVREHLNYW------YSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTSQPMELERVS 691
                   |..:.|.||      .|..|.:.||...|....|:...|| |.::|..:.|......:
plant   901 -------FSVDKLQYWRESAAGISSLAHFMAKDTMDHLNTIMKPLVY-LSMFYFFNNPRSSFEDN 957

  Fly   692 MFVLICVLNSLVAQSLGLLIGAGMNIETGVFLGPVTTIPTILFSGFFVNFDTIPGYLQWVTYVSY 756
            ..||:|::..:                ||     :..|..||:|         |...|.::.:..
plant   958 YIVLVCLVYCV----------------TG-----MAYIFAILYS---------PSAAQLLSVLVP 992

  Fly   757 VRYGFEGAMVAIYGMDRAKMQCNQM--YCHYRVPKKFLEEMSMDNAL----FWVDA--------- 806
            |      .|..|...|:..|....:  :|:   ||..||...:.||.    .||..
plant   993 V------VMTLIANQDKESMVLKYLGSFCY---PKWTLEAFVLSNAQRYSGVWVVTRCSSLSQNG 1048

  Fly   807 ----------VALIGIFFALRIIAYFVL 824
                      :.|:.:....|.||||.:
plant  1049 YDLSDWILCLIVLVLMGLICRFIAYFCM 1076

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	179/741 (24%)
		ABCG_EPDR	142..366	CDD:213180	84/230 (37%)
		ABC2_membrane	564..767	CDD:279410	42/208 (20%)
NAP12	NP_001323430.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810