DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and ABCG31

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_180555.2	Gene:	ABCG31 / 817544	AraportID:	AT2G29940	Length:	1426	Species:	Arabidopsis thaliana

Alignment Length:	727	Identity:	181/727 - (24%)
Similarity:	311/727 - (42%)	Gaps:	165/727 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 QKKGTIALSHLPQRPPVDIEFCDISYSV---TDSHRRGFK----TILKSVSGKFRNGEITAIMGP 184
            :|||.|    ||.: |:.:.|.:::|.|   .:...:|..    .:|.:|||.|..|.:||::|.
plant   813 EKKGMI----LPFK-PLTMTFHNVNYYVDMPKEMRSQGVPETRLQLLSNVSGVFSPGVLTALVGS 872

  Fly   185 SGAGKSTLMNILAGYKT-AQLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAAN 248
            |||||:|||::|||.|| ....|.:.|:...:..:.|.::|.|:.|:|:....:||.|::..:|:
plant   873 SGAGKTTLMDVLAGRKTGGYTEGDIRISGHPKEQQTFARISGYVEQNDIHSPQVTVEESLWFSAS 937

  Fly   249 LKLGKNMISYAKVVVVEEILETIGLKESVNTL---------TCNLSGGQRKRLSIALELVNNPPV 304
            |:|.|.:....|...||:::..:.|    :||         |..||..|||||:||:|||.||.:
plant   938 LRLPKEITKEQKKEFVEQVMRLVEL----DTLRYALVGLPGTTGLSTEQRKRLTIAVELVANPSI 998

  Fly   305 MFFDEPTSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQ-GQCVYEGRV 368
            :|.||||||||:.....::..:|:....|||:||||||||..:||.||.|.|:.: ||.:|.|::
plant   999 IFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFEAFDELLLMKRGGQVIYGGKL 1063

  Fly   369 ----KGLVPYLSSLGYECP--SYHNPADYVLEVASGEYGDAVPKLVDAVKSGACKKYAHKDYVLT 427
                :.||.|...:....|  |.:|||.::|||.:       |.|             .:.|.:.
plant  1064 GTHSQVLVDYFQGINGVPPISSGYNPATWMLEVTT-------PAL-------------EEKYNME 1108

  Fly   428 LAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQNSD 492
            .|      |:.|.|              |:...:|....:.|:|   |...:|....::.|||.
plant  1109 FA------DLYKKS--------------DQFREVEANIKQLSVP---PEGSEPISFTSRYSQNQ- 1149

  Fly   493 CSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTSG 557
                                              .|..:.|:
plant  1150 ----------------------------------LSQFLLCL----------------------- 1157

  Fly   558 WTQ---FWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNE---ASKIMSNAGCIFF 616
            |.|   :|           |......:||....|...|:|.:::|:|::   :..:::..|.::.
plant  1158 WKQNLVYW-----------RSPEYNLVRLVFTTIAAFILGTVFWDIGSKRTSSQDLITVMGALYS 1211

  Fly   617 VSLF---TTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVY 678
            ..||   :..:::.|.:   ..|.:||.||.....|:...:..|:.:.::|:.:..:.:|.::.|
plant  1212 ACLFLGVSNASSVQPIV---SIERTVFYREKAAGMYAPIPYAAAQGLVEIPYILTQTILYGVITY 1273

  Fly   679 YLTSQPMELERVSMFVLICVLNSLVAQSLGLL-IGAGMNIETGVFLGPVTTIPTILFSGFFVNFD 742
            :.........:..::::...|........|:: :|...|......:.........|.|||.|...
plant  1274 FTIGFERTFSKFVLYLVFMFLTFTYFTFYGMMAVGLTPNQHLAAVISSAFYSLWNLLSGFLVQKP 1338

  Fly   743 TIPGYLQWVTYVSYVRYGFEGAMVAIYGMDRAKMQCNQMYCHYRVPKKFLE-EMSMDNALFWVDA 806
            .||.:..|..|:..|.:..:|.:::..|  ..:...|:...|..| |:|:| .......:..|.|
plant  1339 LIPVWWIWFYYICPVAWTLQGVILSQLG--DVESMINEPLFHGTV-KEFIEYYFGYKPNMIGVSA 1400

  Fly   807 VALIG---IFFA 815
            ..|:|   :||:
plant  1401 AVLVGFCALFFS 1412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	177/717 (25%)
		ABCG_EPDR	142..366	CDD:213180	92/241 (38%)
		ABC2_membrane	564..767	CDD:279410	37/209 (18%)
ABCG31	NP_180555.2	PLN03140	17..1426	CDD:215599	181/727 (25%)
		ABC_trans_N	77..151	CDD:291196
		ABCG_PDR_domain1	155..416	CDD:213200
		ABC2_membrane	517..723	CDD:279410
		PDR_assoc	730..793	CDD:285559
		ABCG_PDR_domain2	823..1061	CDD:213199	92/241 (38%)
		ABC2_membrane	1156..1361	CDD:279410	41/241 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324553at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920