DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atet and CG32091

DIOPT Version :9

Sequence 1:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_729728.1	Gene:	CG32091 / 39307	FlyBaseID:	FBgn0052091	Length:	623	Species:	Drosophila melanogaster

Alignment Length:	697	Identity:	225/697 - (32%)
Similarity:	367/697 - (52%)	Gaps:	107/697 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 DIEFCDISYSVTDSHRRGF------KTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGYKTA 202
            ::||.|:.|:|.:  |:.|      :.||..|||.||||:::|||||||||||:|:|.::|::..
  Fly    14 NVEFQDVYYTVKE--RKNFWRVTGERRILNGVSGSFRNGQLSAIMGPSGAGKSSLLNAISGFRRD 76

  Fly   203 QLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEI 267
            .::|         |::..|..:|||.|||.....|||.|.|.:|.:||| ||  .:.|..::.:|
  Fly    77 GVTG---------NIKMKRDNACYITQDDHHQTLLTVEELMNLACDLKL-KN--RHKKAEIMTDI 129

  Fly   268 LETIGLKESVNTLTCNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARG 332
            ||.:.|....|.....||||:|||||||||||:||.:.|.||||||||..|..|.|.||:::|..
  Fly   130 LENLHLNHRRNVTAEKLSGGERKRLSIALELVDNPNIFFLDEPTSGLDEVTAAQCIRLLQAMAYE 194

  Fly   333 GRTIVCTIHQPSARLFEKFDHLYLLAQGQCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVAS 397
            |||||||||||||.::..||.:|:||:|||||:|..:..:|:|.....:||.:::|:||::|:..
  Fly   195 GRTIVCTIHQPSATIYNYFDSIYVLAKGQCVYQGSPRATIPFLRLAQLDCPRHYSPSDYIIELVD 259

  Fly   398 GEYGDAVPKLVDAVKSGACKKYAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLE 462
            .|.|..||.|.|..::|..      .||::.:::           ...:.|:..:.||.:|.|.
  Fly   260 AEDGHLVPALSDLTENGKL------IYVVSQSEQ-----------LAPQQAVTTMFLEQQKRPF- 306

  Fly   463 DRQLEPSIPVDDPAELKPPKLETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGP 527
                                               :|.                 ...||.:...
  Fly   307 -----------------------------------LPA-----------------FFAGSAASTD 319

  Fly   528 SAVVGCMTSLLDSHESVVTLPNKTGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAI 592
            ..::|..::||:..::.....:.......|:.||.:|::.....|.|.::...::||.|::.|..
  Fly   320 GTLIGGTSALLEQVKAFSKRLHTDRRDVCGFRQFIVLMRIMLLRITRARLALTIQLFHHLLCGLF 384

  Fly   593 IGMIYYDVGNEASKIMSNAGCIFFVSLFTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFA 657
            .|:|::.:||:.:::..:........|...:|.:|..||::|.|:.:..:|..|.||:|..:|.|
  Fly   385 FGLIFFQLGNQGARMFDHLKFCIGAVLMIVYTQVMVPILSYPAEVKLVKKETFNRWYTLTPYYMA 449

  Fly   658 KTIADMPFQIVFSSVYVLVVYYLTSQPMELERVSMFVLICVLNSLVAQSLGLLIGAGMNIETGVF 722
            .|::.:|.|::.:..::.|.|:::..|.:..|..:||.:.::.||||:.:||.|||..:|..|..
  Fly   450 LTVSRLPVQVLLNITFMAVTYWMSGLPQQFWRFCIFVAVGLMISLVAEGMGLAIGATFSITNGSV 514

  Fly   723 LGPVTTIPTILFSGFFV-NFDTIP---GYLQWVTYVSYVRYGFEGAMVAIYGMDRAKMQCNQMYC 783
            :||:...|.:   |..| .||..|   |.:|.:...||||.|....::|::|..|.::.|:.:||
  Fly   515 VGPMLIAPLM---GLAVYGFDFAPQVSGGMQLLMKFSYVRVGVVSLVLAVFGFQREELDCDAIYC 576

  Fly   784 HYRVPK---KFL--EEMSMDNALFWVDAVALIGIFFALRIIAYFVLR 825
            |:..|:   |||  |::||   |.....:|::.:||  |::.|..||
  Fly   577 HFSDPRVLLKFLDVEKVSM---LHQFGLLAMLMLFF--RVMMYISLR 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	223/695 (32%)
		ABCG_EPDR	142..366	CDD:213180	111/227 (49%)
		ABC2_membrane	564..767	CDD:279410	60/206 (29%)
CG32091	NP_729728.1	P-loop_NTPase	15..228	CDD:304359	111/226 (49%)
		3a01204	30..620	CDD:273361	219/679 (32%)
		ABC2_membrane	356..558	CDD:279410	60/204 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438895
Domainoid	1	1.000	87	1.000	Domainoid score	I417
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	1	1.000	-	-		mtm14984
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
	9	8.850