Protein Alignment Atet and Abcg4

DIOPT Version :10

• Sequence 1: NP_523471.2
• Gene: Atet / 33636
• FlyBaseID: FBgn0020762
• Length: 832
• Species: Drosophila melanogaster
• Sequence 2: NP_620405.3
• Gene: Abcg4 / 192663
• MGIID: 1890594
• Length: 646
• Species: Mus musculus
• Alignment Length: 745
• Identity: 347/745 - (46%)
• Similarity: 460/745 - (61%)
• Gaps: 132/745 - (17%)

  Fly   104 GLGSNNHALAPKVANNSGGSP---------------NGQKKGTIALSHLPQRPPVDIEFCDISYS 153
            |.|....|:|..|....|..|               ..|:     .||||:|..|||||.::|||
Mouse    10 GCGLGPGAVAMAVTLEDGAEPPVLTTHLKKVENHITEAQR-----FSHLPKRSAVDIEFVELSYS 69

  Fly   154 VTDS---HRRGFKTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGYKTAQLSGSVLINSKER 215
            |.:.   .:||:||:||.:||||...|:..|||||||||||.|||||||:.:.:.|.:|:|.:.|
Mouse    70 VREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPR 134

  Fly   216 NLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEILETIGLKESVNTL 280
            .||.|||:||||||||:|:.:|||.|||||:|||||.:.  ...|..:|.|||..:||....:|.
Mouse   135 ELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK--QEVKKELVTEILTALGLMSCSHTR 197

  Fly   281 TCNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPSA 345
            |..|||||||||:|||||||||||||||||||||||::|||::||::|||.||||::||||||||
Mouse   198 TALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAHGGRTVICTIHQPSA 262

  Fly   346 RLFEKFDHLYLLAQGQCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYGDAVPKLVDA 410
            :|||.||.||:|:||||:::|.|..|:|||..||..||:||||||:::|||||||||..|.|..|
Mouse   263 KLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYGDLNPMLFRA 327

  Fly   411 VKSGACKKYAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDP 475
            |::|.|          |:|:|         ..|..:|                     .:|...|
Mouse   328 VQNGLC----------TMAEK---------KSSPGKN---------------------ELPAHCP 352

  Fly   476 AELKPPKLETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDS 540
            .  .||:|:.                                                    ::|
Mouse   353 T--CPPELDP----------------------------------------------------IES 363

  Fly   541 HESVVTLPNKTGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEAS 605
            |.          |.||..|||.||.:|:|.:||||.:|||:|..|||::|.:||::|..:|::||
Mouse   364 HT----------FATSTLTQFCILFRRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYLHIGDDAS 418

  Fly   606 KIMSNAGCIFFVSLFTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFS 670
            |:.:|.|.:||..||..|.|:|||:||||.||:||:||||||||:|||:|.|||:||:|||:|..
Mouse   419 KVFNNTGFLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYTLKAYYLAKTMADVPFQVVCP 483

  Fly   671 SVYVLVVYYLTSQPMELERVSMFVLICVLNSLVAQSLGLLIG-AGMNIETGVFLGPVTTIPTILF 734
            .||..:||::|.||.|..|..:|..:.:..:||||||||||| |..:::...|:||||.||.:||
Mouse   484 VVYCSIVYWMTGQPAETSRFLLFSALAIATALVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLF 548

  Fly   735 SGFFVNFDTIPGYLQWVTYVSYVRYGFEGAMVAIYGMDRAKMQCNQMYCHYRVPKKFLEEMSMDN 799
            |||||:|.|||.||||.:|:|||||||||.::.||||:|..:.|....|.:|.|:..|.|:.::.
Mouse   549 SGFFVSFKTIPTYLQWSSYLSYVRYGFEGLILTIYGMERGHLTCLDEQCPFRDPQIILRELDVEE 613

  Fly   800 ALFWVDAVALIGIFF-ALRIIAYFVLRWKL 828
            |..::|.:.| |||| |||::||.|||:::
Mouse   614 AKLYMDFLVL-GIFFLALRLLAYLVLRYRV 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_523471.2	3a01204	137..825	CDD:273361	335/692 (48%)
Abcg4	NP_620405.3	3a01204	44..646	CDD:273361	340/711 (48%)