Protein Alignment Atet and Abcg8

DIOPT Version :9

• Sequence 1: NP_001097079.1
• Gene: Atet / 33636
• FlyBaseID: FBgn0020762
• Length: 832
• Species: Drosophila melanogaster
• Sequence 2: NP_569098.2
• Gene: Abcg8 / 155192
• RGDID: 620300
• Length: 672
• Species: Rattus norvegicus
• Alignment Length: 633
• Identity: 144/633 - (22%)
• Similarity: 263/633 - (41%)
• Gaps: 150/633 - (23%)

  Fly   166 LKSVSGKFRNGEITAIMGPSGAGKSTLMNILAG--YKTAQLSGSVLINSKERNLRRFRKLSCYIM 228
            ::::|.|.|:|::.||:|.:|.|::||::::.|  :.....||.:.||.:....:..:|...::.
  Rat    88 IRNLSFKVRSGQMLAIIGSAGCGRATLLDVITGRDHGGKMKSGQIWINGQPSTPQLIQKCVAHVR 152

  Fly   229 QDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEILETIGLKESVNTLTCN-----LSGGQ 288
            |.|.|:.||||||.:...|.::|.|......:...||:::..:.|::..||...|     :|||:
  Rat   153 QQDQLLPNLTVRETLTFIAQMRLPKTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGE 217

  Fly   289 RKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEKFDH 353
            |:|:||.::|:.||.::..|||||||||.|...|:..|..||:|.|.::.::|||.:.:|..||.
  Rat   218 RRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVRTLSRLAKGNRLVLISLHQPRSDIFRLFDL 282

  Fly   354 LYLLAQGQCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYGDAVPKLVDAVKSGACKK 418
            :.|:..|..:|.|..:.:|.|.:|:||.||.|.||||:.:::.|
  Rat   283 VLLMTSGTPIYLGVAQHMVQYFTSIGYPCPRYSNPADFYVDLTS--------------------- 326

  Fly   419 YAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKL 483
                                                      ::.|..|..:...:.|.|. ..|
  Rat   327 ------------------------------------------IDRRSKEQEVATMEKARLL-AAL 348

  Fly   484 ETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLP 548
            ..::.|..|..:......::|......|...||:...|:.:..|..:
  Rat   349 FLEKVQGFDDFLWKAEAKSLDTGTYAVSQTLTQDTNCGTAAELPGMI------------------ 395

  Fly   549 NKTGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSH----VIVGAIIGMIYYDVGNEASKIMS 609
                      .||..|::|......||.    ..||.|    .::..|||.:||...::....|.
  Rat   396 ----------QQFTTLIRRQISNDFRDL----PTLFIHGAEACLMSLIIGFLYYGHADKPLSFMD 446

  Fly   610 NAGCIFFVSLFTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYV 674
            .|..:|.:.....|..::..:....:|.|:...|..:..|:...::|||.:.::|....:..:|.
  Rat   447 MAALLFMIGALIPFNVILDVVSKCHSERSLLYYELEDGLYTAGPYFFAKVLGELPEHCAYVIIYG 511

  Fly   675 LVVYYLTS-QP------MELERVSMFVLICVLNSLVAQSLGLLIGAGMNIETGVFLGPVTTIPTI 732
            :.:|:||: :|      :....:.:.|..|...:|.|.::                     :||.
  Rat   512 MPIYWLTNLRPGPELFLLHFMLLWLVVFCCRTMALAASAM---------------------LPTF 555

  Fly   733 ---------------LFSGFFVNFDTIPGYLQWVTYVSYVRYGFEGAM 765
                           |.:||.:|.:.:.....|::.:|::|:.|.|.|
  Rat   556 HMSSFCCNALYNSFYLTAGFMINLNNLWIVPAWISKMSFLRWCFSGLM 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	144/633 (23%)
		ABCG_EPDR	142..366	CDD:213180	70/206 (34%)
		ABC2_membrane	564..767	CDD:279410	45/228 (20%)
Abcg8	NP_569098.2	ABCG_White	60..295	CDD:213201	70/206 (34%)
		3a01204	88..662	CDD:273361	144/633 (23%)
		ABC2_membrane	401..605	CDD:279410	45/228 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335092
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740