DRSC/TRiP Functional Genomics Resources

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Protein Alignment bdl and CD276

DIOPT Version :9

Sequence 1:NP_608822.1 Gene:bdl / 33635 FlyBaseID:FBgn0028482 Length:719 Species:Drosophila melanogaster
Sequence 2:NP_001019907.1 Gene:CD276 / 80381 HGNCID:19137 Length:534 Species:Homo sapiens


Alignment Length:587 Identity:124/587 - (21%)
Similarity:201/587 - (34%) Gaps:156/587 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 GSALLALLAIILLMNISCTSAARDHRRQTNLEAKVGSHVVFNCYIDFPFDAPIP-------YLVH 70
            |:||.||...:       |.|......:..:.|.||:.....|..     :|.|       .|:.
Human    15 GAALGALWFCL-------TGALEVQVPEDPVVALVGTDATLCCSF-----SPEPGFSLAQLNLIW 67

  Fly    71 WTKDNKKIFTWYEQETSTSELFNGRLHLVENHPEFGRASVNLTAIRESDQGWYHCQVSFPNRSPS 135
            ...|.|::...:.:.......:..|..|..:....|.||:.|..:|.:|:|.:.|.|       |
Human    68 QLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFV-------S 125

  Fly   136 VRNNGTAYHLAVQGGSLIRIPPV----NQTIREGQTAFFHC--VMKHPENSQASWYKDGVLLQEV 194
            :|:.|:| .:::|..:....|.:    |:.:|.|.|....|  ...:|| ::..| :||..:...
Human   126 IRDFGSA-AVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPE-AEVFW-QDGQGVPLT 187

  Fly   195 QDLVRRFYMGPDGSL---SIDPTMMSDLGEYECKVRNSDGELQTAKAFLNIQYK-----AKVIYA 251
            .::.........|..   ||...::...|.|.|.|||...: |.|.:.:.|..:     |..:..
Human   188 GNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQ-QDAHSSVTITPQRSPTGAVEVQV 251

  Fly   252 P--PEVFLPYGQPAVLDCHFRANPPLK----NLRWEKDGLLFDSYNV------------------ 292
            |  |.|.| .|..|.|.|.|...|...    ||.|:    |.|:..:                  
Human   252 PEDPVVAL-VGTDATLRCSFSPEPGFSLAQLNLIWQ----LTDTKQLVHSFTEGRDQGSAYANRT 311

  Fly   293 ---PGVFYKMNGSLFFAKVDENHAGSYTC-TPYNDLGTDGPSPVISVIVLRP---PIFSVTPKAI 350
               |.:..:.|.||...:|.....||:|| ....|.|    |..:|:.|..|   |..::.|...
Human   312 ALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFG----SAAVSLQVAAPYSKPSMTLEPNKD 372

  Fly   351 YIQKLGEAAELPCEAIDRDGNNRPSIIWGRKDGQPLPADRFSLSGGNLTITGLVEGDRGIYECSA 415
            .  :.|:...:.|.:.  .|.....:.|  :|||.:|..      ||:| |..:..::|:::..:
Human   373 L--RPGDTVTITCSSY--RGYPEAEVFW--QDGQGVPLT------GNVT-TSQMANEQGLFDVHS 424

  Fly   416 TNEAATITAEAELMIENIAPRAPYNLTANSTETC--------------ITIRWQPGYLRPN---- 462
            .....                    |.||.|.:|              :||..||....|.    
Human   425 VLRVV--------------------LGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWV 469

  Fly   463 --------------LEYTVWYRLMEAPEWRTLRVLDKK-VMEATVQHLQPGKEYEFMVLSQDKYG 512
                          |.:..|.::.::.|.......|:. ..|.:...|||.|.      |..|..
Human   470 TVGLSVCLIALLVALAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKH------SDSKED 528

  Fly   513 DG 514
            ||
Human   529 DG 530

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bdlNP_608822.1 IG_like 42..128 CDD:214653 19/92 (21%)
Ig 43..131 CDD:299845 20/94 (21%)
I-set 153..242 CDD:254352 22/97 (23%)
Ig 157..242 CDD:299845 21/93 (23%)
Ig_2 252..337 CDD:290606 28/112 (25%)
IG_like 260..327 CDD:214653 22/92 (24%)
I-set 341..428 CDD:254352 15/86 (17%)
IGc2 356..419 CDD:197706 13/62 (21%)
FN3 435..524 CDD:238020 23/113 (20%)
FN3 554..636 CDD:238020
CD276NP_001019907.1 IG_like 37..138 CDD:214653 24/113 (21%)
Ig 43..139 CDD:299845 23/108 (21%)
Ig 148..231 CDD:299845 20/85 (24%)
IG_like 156..237 CDD:214653 20/83 (24%)
IG_like 255..356 CDD:214653 27/109 (25%)
Ig 261..357 CDD:299845 24/103 (23%)
Ig 366..449 CDD:299845 19/115 (17%)
IG_like 374..456 CDD:214653 19/112 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 498..534 10/39 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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