Protein Alignment bdl and Myot

DIOPT Version :10

• Sequence 1: NP_608822.1
• Gene: bdl / 33635
• FlyBaseID: FBgn0028482
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: XP_006526194.1
• Gene: Myot / 58916
• MGIID: 1889800
• Length: 497
• Species: Mus musculus
• Alignment Length: 531
• Identity: 105/531 - (19%)
• Similarity: 185/531 - (34%)
• Gaps: 120/531 - (22%)

  Fly    23 ILLMNISCTSAARDHRRQTNLEAKVGSHVVF--NCYIDFPFDAPIPYLVHWTKDNKKIFTWYEQE 85
            |::....||      .::.:..:.|.||:..  :.|       |.|..:......:|:...|.|
Mouse    40 IVIQPRQCT------EQRFSASSTVSSHITVSSSAY-------PAPQQLAGPNPGQKVTATYNQ- 90

  Fly    86 TSTSELFNGRLHLVENHPEFGRASVNLTAIRESDQGWYHCQVSFP---------NRSPSVRNNGT 141
             |.:...:.   ::.:.|::..:.:..|.    |..:....|:.|         |..|:.:   |
Mouse    91 -SPASFLSS---ILPSQPDYCNSKIPSTV----DSNYQQSSVNQPVNAMSSQAANARPTPK---T 144

  Fly   142 AYHLAVQGGSLIRIPPVNQTIREGQTAFFHCVMKHPENSQASWYKDGVLLQEVQDLVRRFYMGPD 206
            ..| .:||.....|..:.:.::...|      :.|..|.:.::          ::.:.|..:||.
Mouse   145 PDH-EIQGSKEALIQDLERKLKCKDT------LLHNGNQRLTY----------EEKMARRLLGPQ 192

  Fly   207 GSLSIDPTMMSDLGEY--------------ECKVR---NSDGELQTAKAFLNIQYKAKVIYAPPE 254
            .:.::.....||:.:.              ..:||   :|..|.....|.....|..:.|..|..
Mouse   193 NAAAVFQAQNSDVQDSPQQHNPEQARLHVPTSQVRSRSSSRAEANDQDAIQEKFYPPRFIQVPEN 257

  Fly   255 VFLPYGQPAVLDCHFRANP-PLKNLRWEKDGLLFDSYNVPGVFYKMNG--SLFFAKVDENHAGSY 316
            :.:..|:...:|  |:.:. |..::.|..:|....|..:..:.....|  ||.|..|..:.||.|
Mouse   258 MSIEEGRFCRMD--FKVSGLPAPDVSWYLNGRPVQSDELHKMIVSEKGFHSLIFEVVRASDAGPY 320

  Fly   317 TCTPYNDLGTDGPSPVISVIV---LRPPIFSVTPKAIYIQKLGEAAELPCE--AIDRDGNNRPSI 376
            .|...|..|....:..:.|:.   .|.|:|...|::..:.: ||..:|.|:  ||.     .|.:
Mouse   321 ACVARNRAGEATFTVQLDVLAKEHKRAPMFIFKPQSKKVFE-GETVKLECQISAIP-----PPKL 379

  Fly   377 IWGRKDGQ-PLPADRFSLSGGN-----LTITGLVEGDRGIYECSATNEAATITAEAELMIENIAP 435
            .|.|.:.. ....||.||...|     |.|..:.:.|.|.|..||.|||...|....|
Mouse   380 FWKRNNEMVQFNTDRISLYHDNAGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL------- 437

  Fly   436 RAPYNLTANSTETCITIRWQPGYLRPNLEYTVWYRLMEAPEWRTLRVLDKKVMEATVQHLQPGKE 500
                ::||...:|...    |..||....::.:..|       ..|.||.|      |...|..|
Mouse   438 ----DVTARPIQTLPA----PKQLRVRPTFSKYLAL-------NGRGLDVK------QAFNPEGE 481

  Fly   501 YEFMVLSQDKY 511
            ::.:......|
Mouse   482 FQRLAAQSGLY 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653	13/87 (15%)
		Ig strand C	69..72	CDD:409512	0/2 (0%)
		Ig strand E	108..112	CDD:409512	0/3 (0%)
		Ig strand F	122..127	CDD:409512	0/4 (0%)
		Ig	153..242	CDD:472250	14/105 (13%)
		Ig strand B	168..172	CDD:409544	0/3 (0%)
		Ig strand C	181..185	CDD:409544	0/3 (0%)
		Ig strand E	207..211	CDD:409544	0/3 (0%)
		Ig strand F	221..226	CDD:409544	0/18 (0%)
		Ig strand G	235..238	CDD:409544	0/2 (0%)
		Ig_3	247..322	CDD:464046	18/77 (23%)
		Ig	341..428	CDD:472250	28/94 (30%)
		Ig strand B	359..363	CDD:409353	1/3 (33%)
		Ig strand C	375..380	CDD:409353	1/4 (25%)
		Ig strand E	396..400	CDD:409353	2/8 (25%)
		Ig strand F	410..415	CDD:409353	1/4 (25%)
		Ig strand G	423..426	CDD:409353	1/2 (50%)
		FN3	435..524	CDD:238020	15/77 (19%)
		FN3	554..636	CDD:238020
Myot	XP_006526194.1	Ig	249..339	CDD:472250	20/91 (22%)
		Ig strand B	266..270	CDD:409353	1/5 (20%)
		Ig strand C	279..283	CDD:409353	0/3 (0%)
		Ig strand E	305..309	CDD:409353	2/3 (67%)
		Ig strand F	319..324	CDD:409353	2/4 (50%)
		Ig strand G	332..335	CDD:409353	0/2 (0%)
		IgI_Myotilin_C	348..439	CDD:409473	29/107 (27%)
		Ig strand A	348..351	CDD:409473	1/2 (50%)
		Ig strand A'	354..359	CDD:409473	1/4 (25%)
		Ig strand B	364..371	CDD:409473	2/6 (33%)
		Ig strand C	378..384	CDD:409473	1/5 (20%)
		Ig strand C'	385..388	CDD:409473	0/2 (0%)
		Ig strand D	395..401	CDD:409473	2/5 (40%)
		Ig strand E	404..414	CDD:409473	2/9 (22%)
		Ig strand F	418..426	CDD:409473	4/7 (57%)
		Ig strand G	428..439	CDD:409473	3/21 (14%)