DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdl and CG34353

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster

Alignment Length:	479	Identity:	94/479 - (19%)
Similarity:	159/479 - (33%)	Gaps:	124/479 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 GQTAFFHCVMKHPENSQASWYKDGVLLQEVQD----------LVRRFYMGPDGSLSIDPTMMSDL 219
            |:|....|.:.:.:....:| |.|:.:.....          ||..|      :|.|...:.:|.
  Fly   100 GETIVLPCEVANTDTYVVAW-KRGIAILTAGSVKVTPDPRVRLVNGF------NLQIRDALPTDA 157

  Fly   220 GEYECKVRNSDGELQTAKAFLNIQYKAKVIYAPPEVF---------LPYGQPAVLDCHFRANPPL 275
            |:|.|::...|..        .|.:..::: .||.:.         :..|....::|....| |:
  Fly   158 GDYICQIATMDPR--------EITHTVEIL-VPPRIHHISTGGHLQVKKGSSVRIECSATGN-PM 212

  Fly   276 KNLRW-EKDGLLFDSYNVPGVFYKMNGS-LFFAKVDENHAGSYTCTPYNDLGTDGPSPVISVIVL 338
            .|:.| .|:.:|      |....|::.. |....||.:..|.|.||..|.:|....|.|:..::.
  Fly   213 PNVTWSRKNNIL------PNGEEKLHSHVLSIENVDRHKGGVYICTANNRVGQPASSQVVLHVLF 271

  Fly   339 RPPIFSVTPKAIYIQKLGEAAELPCEAIDRDGNNRPSIIWGRKDGQPLPADRFSL----SGGNLT 399
            .|.| ||....::..: |..|.|.|..   .|..:|.:||.:...|....:|..:    |...|.
  Fly   272 SPEI-SVERPVVFSGE-GHEATLVCIV---HGETQPEVIWFKDTMQLDTTERHIMETRGSRHTLI 331

  Fly   400 ITGLVEGDRGIYECSATNE------AATITAEAELMIENIAPRAPYNLTANSTETCITIRWQPGY 458
            |..:...|.|.|.|.|.|:      ...::.:..:.:.|..|.:.|....|       |.|....
  Fly   332 IRKVHPQDFGNYSCVAENQLGKARKTLQLSGKPNVAVFNSPPISQYKDRYN-------ISWAVDS 389

  Fly   459 LRPNLEYTVWYRLMEAPEWRTLRVLDKKVMEATVQHLQPGKEYEFMVLSQDKYGDGMFSKQFRFQ 523
            ..|..||.:.:|.:..........:|.....:::..           .|...||.|:.:
  Fly   390 HSPIEEYKLSFRKLPQGHEVVGNAIDSSSSSSSMSS-----------SSSQMYGSGLHA------ 437

  Fly   524 TLPSPIRADDFDAQQLQHDLGQVTAPAGGLGAPWNLTAISNQQGWLLHWEH-----------PV- 576
                             |.:|.......||....:.:...|    ::||.|           ||
  Fly   438 -----------------HRIGSNMGGLSGLSGSGSYSGYGN----VIHWGHNDWRNVVLPAVPVS 481

  Fly   577 ----QGLEGLRLYAVRWWKEPEHF 596
                ||:.    |.||.....:|:
  Fly   482 HHYAQGMS----YMVRGLDPDQHY 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653
		Ig	43..131	CDD:299845
		I-set	153..242	CDD:254352	16/86 (19%)
		Ig	157..242	CDD:299845	16/86 (19%)
		Ig_2	252..337	CDD:290606	23/95 (24%)
		IG_like	260..327	CDD:214653	19/68 (28%)
		I-set	341..428	CDD:254352	22/96 (23%)
		IGc2	356..419	CDD:197706	19/72 (26%)
		FN3	435..524	CDD:238020	14/88 (16%)
		FN3	554..636	CDD:238020	12/59 (20%)
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	17/95 (18%)
		Ig	103..177	CDD:143165	15/88 (17%)
		IG_like	191..269	CDD:214653	21/84 (25%)
		IGc2	198..258	CDD:197706	18/66 (27%)
		I-set	273..360	CDD:254352	23/91 (25%)
		Ig	290..359	CDD:143165	18/71 (25%)
		FN3	<466..524	CDD:238020	9/40 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810