DRSC/TRiP Functional Genomics Resources

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Protein Alignment bdl and prtga

DIOPT Version :10

Sequence 1:NP_608822.1 Gene:bdl / 33635 FlyBaseID:FBgn0028482 Length:719 Species:Drosophila melanogaster
Sequence 2:NP_001038495.1 Gene:prtga / 563834 ZFINID:ZDB-GENE-061204-4 Length:1149 Species:Danio rerio


Alignment Length:602 Identity:155/602 - (25%)
Similarity:242/602 - (40%) Gaps:115/602 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 VVFNCYIDFPFDAPIPYLVHWTKDNKKIFTWYEQETSTSELFNGRLHL--VENHPEFGRASVNLT 113
            ||.:|...  .:|||.  :.|.|:.   .|..|.|...| |.||.|.:  ||:..:         
Zfish    44 VVLDCQAH--GEAPIG--IRWLKNG---VTITESERVYS-LSNGSLLISEVESRKD--------- 91

  Fly   114 AIRESDQGWYHCQVSFPNRSPSVRNNGTAYHLAVQGGSLIRIPPVNQTIREGQTAFFHCVMKHPE 178
               :||:|:|.|...  |:..|:.:...  .|.:...|.....|.:..:.||..|.|.|.:....
Zfish    92 ---KSDEGFYQCLAQ--NKYGSILSQRA--RLTIASLSTFTQQPASIIVMEGSVARFTCKITATP 149

  Fly   179 NSQASWYKDGVLLQEVQDLVRRFYMGPDGSLSIDPTMMSDLGEYECKVRNSDGELQTAKAFLNI- 242
            ....:|..:.|.|....:   |..:.|.|.|.|......|.|.|.|...|.....::.:|.|.: 
Zfish   150 PPIITWEFNRVTLPLATE---RITVLPSGVLQIQGVEQRDAGSYRCVAANIVSRRRSTEATLTVT 211

  Fly   243 -------QYKAKVIYAPPEVFLPYGQPAVLDCHFRANP-PLKNLRWEK-DGLLFDSY--NVPGVF 296
                   ..:.::|..|..:.:|....|:|:|....|| ||  :.|.: |....|.:  .|.|  
Zfish   212 PAMSPRAPQRPRIIAGPQNLTVPAHSTALLECMASGNPRPL--ISWSRADHKSIDVHKTKVLG-- 272

  Fly   297 YKMNGSLFFAKVDENHAGSYTC---TPYNDLGTDGPS-PVISVIVLRPPIFSVTPKAIYIQKLGE 357
               ||:|..:.|:..|||.|.|   ||    ||...: ...::.||.||.....|:::...:.| 
Zfish   273 ---NGNLIISDVNPQHAGIYFCRATTP----GTRNYTIAAANITVLAPPSLVEWPESVTRPRAG- 329

  Fly   358 AAELPCEAIDRDGNNRPSIIWGRKDGQPLPAD-RFSLSGGNLTITGLVEGDRGIYECSATNEAAT 421
            .|...|.|   :|...|.|.| .|:|:|:.:: |..:....|.|..::..|.|||:|.|.|...:
Zfish   330 TARFVCTA---EGFPTPQITW-LKNGEPVRSNGRIKMYNSKLVINQIIPEDDGIYQCEAENIQGS 390

  Fly   422 ITAEAELMI--ENIAPRAPYNLTANS-TETCITIRW-QPGYLRPNLE----YTVWYRLMEA---P 475
            :.|.|.|::  .:..|.||.|:.|:: :.:.|.:.| :|.|   |.|    |:|.|...|.   .
Zfish   391 VLAMARLIVVMSDNRPSAPRNIRADTVSSSAIVLAWDRPAY---NSEKVIAYSVHYMKAEGLNNE 452

  Fly   476 EWRTLRVLDKKVMEATVQHLQPGKEYEFMVLSQDKYGDGMFSKQFRFQTLPS-PIRADDFDA--- 536
            |::.  |:........:..|:.|:.|.|.:::....|....|......||.. |:||.:...   
Zfish   453 EYQI--VIGNDTTRYIIDDLEAGRNYTFYIVAYMPMGASRMSDHVIQHTLEDVPLRAPELSLTSR 515

  Fly   537 ---------QQLQHDL--GQVTAPAGGLGAPWNLTAISNQQGWLLHWE---HPV-QGLEGLR--- 583
                     |.|.|.|  |:|:|        :.|:..::..|.|...|   |.. |.||||:   
Zfish   516 SPSDIQVSWQPLSHKLSRGRVSA--------YRLSYRTSSDGTLTQLELSAHKTHQLLEGLQPDT 572

  Fly   584 LYAVR-------WWKEP 593
            .|.:|       .|.||
Zfish   573 TYLLRIAAATAVGWGEP 589

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bdlNP_608822.1 IG_like 42..128 CDD:214653 23/78 (29%)
Ig strand C 69..72 CDD:409512 0/2 (0%)
Ig strand E 108..112 CDD:409512 0/3 (0%)
Ig strand F 122..127 CDD:409512 2/4 (50%)
Ig 153..242 CDD:472250 21/88 (24%)
Ig strand B 168..172 CDD:409544 2/3 (67%)
Ig strand C 181..185 CDD:409544 0/3 (0%)
Ig strand E 207..211 CDD:409544 2/3 (67%)
Ig strand F 221..226 CDD:409544 2/4 (50%)
Ig strand G 235..238 CDD:409544 0/2 (0%)
Ig_3 247..322 CDD:464046 26/81 (32%)
Ig 341..428 CDD:472250 25/87 (29%)
Ig strand B 359..363 CDD:409353 1/3 (33%)
Ig strand C 375..380 CDD:409353 2/4 (50%)
Ig strand E 396..400 CDD:409353 1/3 (33%)
Ig strand F 410..415 CDD:409353 3/4 (75%)
Ig strand G 423..426 CDD:409353 1/2 (50%)
FN3 435..524 CDD:238020 23/97 (24%)
FN3 554..636 CDD:238020 15/54 (28%)
prtgaNP_001038495.1 IgI_1_Neogenin_like 26..118 CDD:409387 26/97 (27%)
Ig strand A 26..29 CDD:409387
immunoglobulin domain 28..118 26/97 (27%)
Ig strand A' 32..38 CDD:409387
Ig strand B 42..52 CDD:409387 3/9 (33%)
Ig strand C 56..62 CDD:409387 2/7 (29%)
Ig strand C' 64..67 CDD:409387 0/5 (0%)
Ig strand D 72..77 CDD:409387 1/5 (20%)
Ig strand E 79..85 CDD:409387 2/5 (40%)
Ig strand F 96..103 CDD:409387 3/6 (50%)
Ig strand G 107..118 CDD:409387 2/12 (17%)
immunoglobulin domain 122..211 22/91 (24%)
I-set 124..210 CDD:400151 21/88 (24%)
Ig strand B 139..143 CDD:409353 2/3 (67%)
Ig strand C 152..156 CDD:409353 0/3 (0%)
Ig strand E 175..179 CDD:409353 2/3 (67%)
Ig strand F 189..194 CDD:409353 2/4 (50%)
Ig strand G 203..206 CDD:409353 0/2 (0%)
Ig_3 221..294 CDD:464046 24/79 (30%)
immunoglobulin domain 222..309 28/97 (29%)
immunoglobulin domain 314..384 21/74 (28%)
I-set 330..399 CDD:400151 23/72 (32%)
Ig strand B 332..335 CDD:409353 0/2 (0%)
Ig strand C 344..348 CDD:409353 2/4 (50%)
Ig strand E 365..369 CDD:409353 1/3 (33%)
Ig strand F 379..384 CDD:409353 3/4 (75%)
Ig strand G 392..395 CDD:409353 1/2 (50%)
FN3 406..499 CDD:238020 23/97 (24%)
fibronectin type III domain 406..491 22/89 (25%)
fibronectin type III domain 504..590 25/94 (27%)
FN3 507..597 CDD:238020 23/91 (25%)
fibronectin type III domain 606..690
fn3 608..686 CDD:394996
fibronectin type III domain 710..794
FN3 <715..>901 CDD:442628
fibronectin type III domain 806..895
FN3 809..901 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1060..1149
Blue background indicates that the domain is not in the aligned region.

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