DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdl and Fcrlb

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	XP_008767969.1	Gene:	Fcrlb / 498275	RGDID:	1563018	Length:	471	Species:	Rattus norvegicus

Alignment Length:	372	Identity:	80/372 - (21%)
Similarity:	132/372 - (35%)	Gaps:	111/372 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 PEFGRASVNLTAIRESDQGWYH-----CQVS-FPNRSPSVRNNGTAYHLAVQGGSLIRIPPVNQT 161
            |:.|        :.:..|.|..     |.:: .|:..||..:..|...      .::.:.|...|
  Rat    28 PDIG--------VFQQSQSWAFTFGRACHLTLLPHTVPSPTSPATLEK------PVLSLHPPWTT 78

  Fly   162 IREGQTAFFHCVMKHPENSQASWYKDGVLLQEVQDLVRRFYMG----PDGSLSIDPTMMSDLGEY 222
            |.:|:.....|...||            ||.|::.:...:|:|    |....||:   :...|.|
  Rat    79 IFKGERVTLRCDGYHP------------LLLELRPISTLWYLGHVLLPSHKKSIE---VQAPGVY 128

  Fly   223 ECKVRN---SDG-ELQTAKAFLNIQYKAKVIYAPPEVFLPY-----GQPAVLDCHFRANPPLKNL 278
            .|:.|.   ||. .|..:..:|.:|             :||     |:|.|:.|....:..:..|
  Rat   129 RCQTRGAPVSDPIHLSVSNDWLILQ-------------VPYAAVFEGEPLVMRCRGWYDKVVYKL 180

  Fly   279 RWEKDGLLFDSYNVPGVFY---KMNGSLFFAKVDENHAGSYTCTPYNDLGTDGPSPVISVIVLRP 340
            .:..||        ..|.|   ..|.::..|:..:  :|.|.|:     ||      :.:.|...
  Rat   181 HYYHDG--------QAVRYFHSSTNYTVLQARASD--SGHYQCS-----GT------MRIPVESA 224

  Fly   341 PIFSVTPKAIYIQKLGEAAEL----PCEAIDRDGNNRPSIIWGRKDGQPL---------PADRFS 392
            |:|| :..|:.:|:|.:...|    |.||..|......:.:..:|...||         |..||.
  Rat   225 PMFS-SKVAVTVQELFQTPVLRTLSPQEARGRVVLRCETRLHPQKRDTPLQFAFYKYSRPVRRFD 288

  Fly   393 LSGGNLTITGLVEGDRGIYECSATNEAATITAEAELMIENIAPRAPY 439
            . |...|:......:...|.|    ||||.|       .::..|:|:
  Rat   289 W-GAEYTVPEPEVEELESYWC----EAATTT-------RSVRKRSPW 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653	5/29 (17%)
		Ig	43..131	CDD:299845	5/33 (15%)
		I-set	153..242	CDD:254352	23/96 (24%)
		Ig	157..242	CDD:299845	23/92 (25%)
		Ig_2	252..337	CDD:290606	18/92 (20%)
		IG_like	260..327	CDD:214653	15/69 (22%)
		I-set	341..428	CDD:254352	26/99 (26%)
		IGc2	356..419	CDD:197706	15/75 (20%)
		FN3	435..524	CDD:238020	2/5 (40%)
		FN3	554..636	CDD:238020
Fcrlb	XP_008767969.1	Ig	68..145	CDD:416386	22/91 (24%)
		Ig strand A	69..72	CDD:409353	0/2 (0%)
		Ig strand A'	77..80	CDD:409353	1/2 (50%)
		Ig strand B	84..90	CDD:409353	0/5 (0%)
		Ig strand C	104..109	CDD:409353	1/4 (25%)
		Ig strand C'	111..113	CDD:409353	0/1 (0%)
		Ig strand E	118..123	CDD:409353	2/7 (29%)
		Ig strand F	126..131	CDD:409353	2/4 (50%)
		Ig strand G	139..145	CDD:409353	2/5 (40%)
		Ig2_FcgammaR_like	149..235	CDD:409411	25/120 (21%)
		Ig strand B	165..169	CDD:409411	1/3 (33%)
		Ig strand C	179..183	CDD:409411	1/3 (33%)
		Ig strand E	196..200	CDD:409411	1/3 (33%)
		Ig strand F	210..215	CDD:409411	2/9 (22%)
		Ig strand G	228..231	CDD:409411	1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000