DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment bdl and opcml

DIOPT Version :9

Sequence 1:NP_608822.1 Gene:bdl / 33635 FlyBaseID:FBgn0028482 Length:719 Species:Drosophila melanogaster
Sequence 2:NP_001005580.1 Gene:opcml / 449538 ZFINID:ZDB-GENE-040927-3 Length:342 Species:Danio rerio


Alignment Length:360 Identity:84/360 - (23%)
Similarity:135/360 - (37%) Gaps:81/360 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 LALLAIILLMNISCTSAAR--DHRRQTNLEAKVGSHVVFNCYIDFPFDAPIPYLVHWTKDNKKIF 79
            |.::|:.||..:.....||  |...:.|:..:.|...|..|.:|.....     |.|......:|
Zfish    14 LVVVALRLLFLVPAGVPARSGDSYLKDNITVRQGDSAVLKCSMDNKVSR-----VAWLNRTTILF 73

  Fly    80 TWYEQETSTSELFNGRLHLVENHPEFGRASVNLTAIRESDQGWYHCQVSFPNRSPSVRNNGTAYH 144
            |..|:.:     .:.|:.|:  :......|:.:..:...|:|.|.|.: ..|:.|    ..|..|
Zfish    74 TGNEKWS-----LDPRVVLL--NTAVNEYSIKILNVNLYDEGPYVCSI-LTNKKP----ESTKVH 126

  Fly   145 LAVQGGSLIRIPPVNQTIREGQTAFFHCV-MKHPENSQASW----YKDGVLLQEVQDLVRRFYMG 204
            |.||..:.|.....:.::.||......|: :..||.| ..|    .|...::.|.:      |:.
Zfish   127 LIVQVPARIVNVSTDVSVNEGSNVSLMCLAIGRPEPS-ILWKFRSSKGNRIVTEGE------YVE 184

  Fly   205 PDGSLSIDPTMMSDL-GEYECKVRN--SDGELQTAKAFLNIQYKAKVIYAPPEVF------LPYG 260
            ..|       :..|: |.|:|...|  |..:::|.:..:|.         ||.:.      ...|
Zfish   185 MTG-------ITKDMSGSYDCITSNDISPPDVRTVQVTVNY---------PPVISRARSTGTAVG 233

  Fly   261 QPAVLDCHFRANPPLKNLRWEK-DGLLFDSYNVPGVFYKMNGS---LFFAKVDENHAGSYTCTPY 321
            |..||.|...| .||.:.:|.| :..:.:.:|  ||..:..|.   |.|..|.|...|:|||...
Zfish   234 QKGVLWCEASA-VPLADFQWFKGERRILNGFN--GVKIENKGKQSMLTFFNVSEEDYGNYTCVAI 295

  Fly   322 NDLGTD-------GP-----------SPVISVIVL 338
            |.||..       ||           ||..|:::|
Zfish   296 NTLGITNASIILYGPGAIHDVNNAALSPTCSLLLL 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bdlNP_608822.1 IG_like 42..128 CDD:214653 17/85 (20%)
Ig 43..131 CDD:299845 16/87 (18%)
I-set 153..242 CDD:254352 19/96 (20%)
Ig 157..242 CDD:299845 18/92 (20%)
Ig_2 252..337 CDD:290606 32/112 (29%)
IG_like 260..327 CDD:214653 25/70 (36%)
I-set 341..428 CDD:254352
IGc2 356..419 CDD:197706
FN3 435..524 CDD:238020
FN3 554..636 CDD:238020
opcmlNP_001005580.1 Ig 41..129 CDD:299845 22/104 (21%)
IG_like 41..129 CDD:214653 22/104 (21%)
IG_like 139..216 CDD:214653 18/90 (20%)
IGc2 146..202 CDD:197706 15/69 (22%)
I-set 219..307 CDD:254352 27/90 (30%)
ig 223..307 CDD:278476 25/86 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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