DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdl and negr1

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	XP_009300786.1	Gene:	negr1 / 445374	ZFINID:	ZDB-GENE-040822-27	Length:	360	Species:	Danio rerio

Alignment Length:	370	Identity:	74/370 - (20%)
Similarity:	135/370 - (36%)	Gaps:	89/370 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SGSALLALLAIILLMNISCTSAARDHRRQTNLEAKV---GSHVVFNCYIDFPFDAPIPYLVHWTK 73
            ||..|.|::..:.....||..|.:.....|:.|:.|   |...:..||:               .
Zfish    13 SGQWLTAIILSLCCFLPSCLPAGQTVDYTTSSESVVSRQGDTALLRCYL---------------L 62

  Fly    74 DNKKIFTWYEQET---STSELFNG--RLHLVENHPEFGRASVNLTAIRESDQGWYHCQVSFPNRS 133
            |......|..:.:   :.::.::|  |:.:|.|..:....|:.:..:..:|:|.|.|
Zfish    63 DGISKGAWLNRSSIIYAGNDKWSGDPRVSIVSNVGDKHEYSLQIQKVDVTDEGVYTC-------- 119

  Fly   134 PSVRNNGTAYHLAVQGGSLIRIPP------VNQTIREGQTAFFHCVMKHPENSQASWYKDGVLLQ 192
             |:::....:...:|  .::::||      .:.|:.||......|........:.||       :
Zfish   120 -SIQSERNLHPKLIQ--LIVKVPPKIYDISSDITVNEGSNVSLICAASGKPEPKISW-------R 174

  Fly   193 EVQDLVRRFYMGPDGSLSIDPTMMSDLGEYECKVRN--SDGELQTAKAFLNIQYKAKVIYAPPEV 255
            .:....|::..|.  .|:|........|:|||...|  :..:.:|.:..:|.         ||.:
Zfish   175 HISPSARKYESGE--YLNITGISRDQAGDYECGAENDIASPDTKTVRVTVNF---------PPAI 228

  Fly   256 F------LPYGQPAVLDCHFRANP-PLKNLRWEK--------DGLLFDSYNVPGVFYKMNGSLFF 305
            .      :..||.|:|.|...|.| |:  ..|.|        .|::.::.:...|....|
Zfish   229 HEMKSHGVRPGQVALLRCEAAAVPSPV--FEWYKGEKRINMGQGIVINNLSSRSVLTVKN----- 286

  Fly   306 AKVDENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPKAI 350
              :.::..|:|||...|.|||...|     :.|.|.|...|..|:
Zfish   287 --MTQDRYGNYTCVAVNRLGTANAS-----VPLNPIIEPTTTSAV 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653	16/93 (17%)
		Ig	43..131	CDD:299845	16/95 (17%)
		I-set	153..242	CDD:254352	18/96 (19%)
		Ig	157..242	CDD:299845	17/92 (18%)
		Ig_2	252..337	CDD:290606	24/99 (24%)
		IG_like	260..327	CDD:214653	20/75 (27%)
		I-set	341..428	CDD:254352	3/10 (30%)
		IGc2	356..419	CDD:197706
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
negr1	XP_009300786.1	Ig	42..121	CDD:299845	17/102 (17%)
		IG_like	44..136	CDD:214653	18/117 (15%)
		I-set	140..222	CDD:254352	17/90 (19%)
		IGc2	153..208	CDD:197706	13/63 (21%)
		IG_like	236..312	CDD:214653	22/89 (25%)
		IGc2	238..304	CDD:197706	18/74 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900