DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdl and dpr19

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster

Alignment Length:	452	Identity:	89/452 - (19%)
Similarity:	155/452 - (34%)	Gaps:	136/452 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LALLAIILLM-----NISCTSAARDH-----------RRQTNLEAKVGSHVVFNCYIDFPFDAPI 65
            |.|...:||:     ::...:::::|           :..|.:.|:.|...:..|.:    ....
  Fly     8 LHLSCFLLLLSSTFSDVGKITSSQNHFGNTLQSQFNTKNNTRVIAQKGGLAILPCVV----KVNS 68

  Fly    66 PYLVHWTKDNKKIFTWYEQETSTSELFNGRLHLVENHPEFGRASVNLTAIRESDQGWYHCQVS-F 129
            |..|.|.:  :|.|.......||..  :.:..|||:....|..|:.:.|:||.|:|:|.||:| :
  Fly    69 PATVSWIR--RKDFQLLTVGLSTHS--SDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQLSIY 129

  Fly   130 PNRS--------PSVRNNGTAYHLAVQGGSLIRIPPVNQTIREGQTAFFHCVMKHPENSQA--SW 184
            |.:|        .:|....:|..|.:...|.:|:               .|.:|....:.|  .|
  Fly   130 PTQSIVIELKIVEAVAEISSAPELHIDETSTLRL---------------ECKLKRATENPAFVFW 179

  Fly   185 YKDGVLLQEVQDLVRRFYMGPDGSLSIDPTMMSDLGE--------YECKVRNSDG---ELQTAKA 238
            |.|..::.         |....|      .:::.:|:        |.....|...   .::::..
  Fly   180 YHDSKMIN---------YDSQGG------FVVTSIGQSNPQSGQFYRSSPANKSRATMPMESSNG 229

  Fly   239 FLNIQYKAKVIYAPPEVFLPYGQPAVLDCHFRANPPLKNLRWEKDGLLFDSYNVPGVFYKMNGS- 302
            .||....:......|...:|...|.:...|..|                         |.:|.|
  Fly   230 VLNSLLGSSDAIKAPAANVPSSTPYMTQQHQSA-------------------------YLLNPSV 269

  Fly   303 --LFFAKVDENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPKAIYIQKLGEAAELPCEA 365
              |...:|:..|||:|||.|.|               .||.  |:|...:..:|...........
  Fly   270 SVLTVKQVNFRHAGNYTCAPSN---------------ARPA--SITVHVLRGEKTAAMQHANRSI 317

  Fly   366 IDRDGNNRPS---IIWGRKDGQPLPADRFSLSGGNLTITGL------VEGDRGIYECSATNE 418
            :|.:.|...:   |..|..:|    ....:|:||.|..:||      |..||  :..:||::
  Fly   318 LDTETNGNGTFGLITLGGLNG----TSGVTLAGGILYFSGLFLLMGAVVFDR--FSLAATHK 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653	23/85 (27%)
		Ig	43..131	CDD:299845	24/88 (27%)
		I-set	153..242	CDD:254352	13/101 (13%)
		Ig	157..242	CDD:299845	12/97 (12%)
		Ig_2	252..337	CDD:290606	18/87 (21%)
		IG_like	260..327	CDD:214653	16/69 (23%)
		I-set	341..428	CDD:254352	19/87 (22%)
		IGc2	356..419	CDD:197706	16/72 (22%)
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	23/84 (27%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	20/77 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810