DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdl and DIP-theta

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	80/354 - (22%)
Similarity:	126/354 - (35%)	Gaps:	86/354 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NLEAKVGSHVVFNCYIDFPFDAPIPYLVHWTK-DNKKIFTWYEQETSTSELFNGRLHLVENHPEF 105
            |:...|....|..|.:    |....|.:.|.: |.:.|.| .:....|.   |.|:.:  .|.|.
  Fly   138 NVTVPVSREAVLQCVV----DNLQTYKIAWLRVDTQTILT-IQNHVITK---NHRMSI--THAEK 192

  Fly   106 GRASVNLTAIRESDQGWYHCQVSFPNRSPSVRNNGTAYHLAVQGGSL-IRIPP--------VNQT 161
            ....:.:..::|||:|||.||:   |..|          :..|.|.| :.:||        .:..
  Fly   193 RAWILRIRDVKESDKGWYMCQI---NTDP----------MKSQVGYLDVVVPPDILDYPTSTDMV 244

  Fly   162 IREGQTAFFHCVMKHPENSQASWYKDGVLLQEVQDLVRRFYMGPDGS---------LSIDPTMMS 217
            ||||......|..........:|.::|..|..:          |:|:         |:|......
  Fly   245 IREGSNVTLKCAATGSPTPTITWRREGGELIPL----------PNGAEAVAYNGSFLTIAKVNRL 299

  Fly   218 DLGEYECKVRNSDGELQTAKAFLNIQYKAKVIYAPPEVFL-------PYGQPAVLDCHFRANPPL 275
            ::|.|.|...|......:.:..|       :::.||.:::       ...|...|:|...|.|..
  Fly   300 NMGAYLCIASNGIPPTVSKRVML-------IVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKS 357

  Fly   276 KNLRWEKDGLLFDSYNVPG------VF---YKMNGSLFFAKVDENHAGSYTCTPYNDLG-TDGP- 329
            .|. |.|:    |:..|||      .|   ||:...|...:||....|:|.|...|.|| |||.
  Fly   358 INY-WMKN----DTIIVPGERFVPETFESGYKITMRLTIYEVDIQDFGAYRCVAKNSLGDTDGAI 417

  Fly   330 ----SPVISVIVLRPPIFSVTPKAIYIQK 354
                .|..:.:....|..|:....:.:.|
  Fly   418 KLYHIPQTTTMTTMAPTVSINTVPVVLVK 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653	23/86 (27%)
		Ig	43..131	CDD:299845	22/88 (25%)
		I-set	153..242	CDD:254352	19/105 (18%)
		Ig	157..242	CDD:299845	18/101 (18%)
		Ig_2	252..337	CDD:290606	30/106 (28%)
		IG_like	260..327	CDD:214653	24/76 (32%)
		I-set	341..428	CDD:254352	3/14 (21%)
		IGc2	356..419	CDD:197706
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	28/114 (25%)
		IG_like	137..230	CDD:214653	28/114 (25%)
		IG_like	240..324	CDD:214653	17/100 (17%)
		IGc2	247..310	CDD:197706	13/72 (18%)
		Ig	327..419	CDD:299845	29/96 (30%)
		IG_like	343..420	CDD:214653	27/81 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810