DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdl and CG33543

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster

Alignment Length:	374	Identity:	87/374 - (23%)
Similarity:	144/374 - (38%)	Gaps:	59/374 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LLALLAIILLMNISCTSAARDHRRQTNLEAKVGSHVVFNCYIDFPFDAPI------PYLVHWTKD 74
            |:||.:::||: :|..:|.......|:    .|.........|.|...|:      |.:.|:..:
  Fly     4 LIALCSLLLLL-LSQNAAILGQLDSTS----SGGSGTGGAPPDRPPTPPLSLQPSTPSITHFVNE 63

  Fly    75 NKKIF----------TWYEQETSTSELFNGRLHLVENHPEFGRASVNLTAIRESDQGWYHCQVS- 128
            :..||          .|.:....|.|...||:|:.:.  ..|..::....|...|:|.:.|:|:
  Fly    64 SFIIFCQTVQKDIDTKWRDPRGQTRENTKGRVHIEKK--TTGLLALVFEHIALEDRGNWTCEVNG 126

  Fly   129 --FPNRSPSVRNNGTA-YHLAV-QGGSLIRIPPVNQTIREGQTAFFHCVMKHPENSQASWYKDGV 189
              ..||:.:|.....| :.|.| |..|..:...| |::|||:.|..:|.::.....:.||..:|.
  Fly   127 NRNGNRNVNVEREFLASFELLVNQKISFGKTEQV-QSVREGRDAMVNCFVEGMPAPEVSWLYNGE 190

  Fly   190 LLQEVQDLV-RRFYMGPDGSLSIDPTMMSDLGEYECKVRN-----SDGELQTAKAFLNIQYKAKV 248
            .:..|.... .|...|    |.|.....:|.|||.|:...     ||.:..|  ..|.||:|...
  Fly   191 YINTVNSTKHNRLSNG----LYIRNVSQADAGEYTCRAMRITPTFSDSDQIT--ILLRIQHKPHW 249

  Fly   249 IY--APPEVFLPYGQPAVLDCHFRANPPLKNLRWEKDGLLFDSYNVPGVFYKM-----NGSLFFA 306
            .:  ..|..:...|....|.|.....|| .:..|     |.::..:.|..:::     ..:|...
  Fly   250 FFNETLPVQYAYVGGAVNLSCDAMGEPP-PSFTW-----LHNNKGIVGFNHRIFVADYGATLQLQ 308

  Fly   307 KVDENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPKAIYIQKL 355
            ..:.:..|.|.|...|.||.     :..||.|||....:.|:...::||
  Fly   309 MKNASQFGDYKCKVANPLGM-----LERVIKLRPGPKPLGPRRFQLKKL 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653	19/101 (19%)
		Ig	43..131	CDD:299845	20/106 (19%)
		I-set	153..242	CDD:254352	24/94 (26%)
		Ig	157..242	CDD:299845	24/90 (27%)
		Ig_2	252..337	CDD:290606	17/89 (19%)
		IG_like	260..327	CDD:214653	15/71 (21%)
		I-set	341..428	CDD:254352	3/15 (20%)
		IGc2	356..419	CDD:197706	87/374 (23%)
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	17/62 (27%)
		IG_like	256..336	CDD:214653	18/90 (20%)
		IGc2	263..327	CDD:197706	13/69 (19%)
		FN3	341..445	CDD:238020	3/12 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900