DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bdl and Fcrl5

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_899045.3	Gene:	Fcrl5 / 329693	MGIID:	3053558	Length:	596	Species:	Mus musculus

Alignment Length:	267	Identity:	59/267 - (22%)
Similarity:	96/267 - (35%)	Gaps:	72/267 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 NLTAIRESDQGWYHCQVSFPNRSPSVRNNGTAYHLAVQGGSL---IRIPPVNQTIREGQTAFFHC 172
            ::.||...:...|.|:....|  ..|....||:.:.||..|.   ..|.|.::.:.|||....:|
Mouse   263 HIPAIWTEESKRYQCKAETVN--SQVSKQSTAFIIPVQRASARFQTHIIPASKLVFEGQLLLLNC 325

  Fly   173 VMKH-PENSQASWYKDGVLLQEVQDLVRRFYMGPDGSLSIDPTMMSDLGEYECKVRNSDGELQTA 236
            .:|. |...:.||||..:|.:|.:.|     ...:....|....:||.|||.|:..||      .
Mouse   326 SVKGVPGPLKFSWYKKDMLNKETKIL-----KSSNAEFKISQVNISDAGEYYCEANNS------R 379

  Fly   237 KAFLNIQYKAKVIYAPPEVFLPYGQPAV----------------LDCHFRANPPLKNLRWEKDGL 285
            ::|::..:       |..:.:|..||.:                |.|..:...|.         :
Mouse   380 RSFVSRAF-------PITIKVPVSQPVLTLSTGKTQALEGDLMTLHCQSQRGSPC---------I 428

  Fly   286 LFDSYNVPGVFYKM-----------NGSLFFAKVDENHAGSYTCTPYNDLGTDGPSPVISVIVLR 339
            |::      .||:.           .|:.|...:....:|:|.||..|.||.....      .:|
Mouse   429 LYE------FFYENVSLGNSSILSGGGAYFNFSMSTERSGNYYCTADNGLGAQCSE------AIR 481

  Fly   340 PPIFSVT 346
            ..||.:|
Mouse   482 ISIFDMT 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653	4/16 (25%)
		Ig	43..131	CDD:299845	4/19 (21%)
		I-set	153..242	CDD:254352	25/89 (28%)
		Ig	157..242	CDD:299845	24/85 (28%)
		Ig_2	252..337	CDD:290606	19/111 (17%)
		IG_like	260..327	CDD:214653	17/93 (18%)
		I-set	341..428	CDD:254352	3/6 (50%)
		IGc2	356..419	CDD:197706
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
Fcrl5	NP_899045.3	Ig	34..112	CDD:299845
		IG_like	40..101	CDD:214653
		Ig	119..202	CDD:299845
		IG_like	127..200	CDD:214653
		Ig_2	209..297	CDD:290606	8/35 (23%)
		Ig_2	308..391	CDD:290606	26/100 (26%)
		IG_like	310..393	CDD:214653	25/100 (25%)
		Ig_2	398..484	CDD:290606	17/106 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	522..544
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	561..596
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000