DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment bdl and Kirrel1

DIOPT Version :9

Sequence 1:NP_608822.1 Gene:bdl / 33635 FlyBaseID:FBgn0028482 Length:719 Species:Drosophila melanogaster
Sequence 2:XP_006232737.1 Gene:Kirrel1 / 310695 RGDID:727883 Length:805 Species:Rattus norvegicus


Alignment Length:700 Identity:146/700 - (20%)
Similarity:224/700 - (32%) Gaps:196/700 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    61 FDAPIPYLVHWTKDNKKIFTWYEQE---TSTSELFNGR-------LHLVENHPEFGRASVNLTAI 115
            |:|.....:.|.:|..      :||   |||..|.:|:       |.:.....:.||.       
  Rat   178 FNAKPAATIIWFRDGT------QQEGAVTSTELLKDGKRETTISQLLIQPTDLDIGRV------- 229

  Fly   116 RESDQGWYHCQ---VSFPNRSPSVRNNGTAYHLAVQGGSLIRIPPVNQTIREGQTAFFHC-VMKH 176
                   :.|:   .:.||      ...|:..|.|.....:.:....||:.||:...|.| ...:
  Rat   230 -------FTCRSMNEAIPN------GKETSIELDV
HHPPTVTLSIEPQTVLEGERVIFTCQATAN 281

  Fly   177 PENSQASWYKDGVLLQEVQDLVRRFYMGPDGSLSIDPTMMSDLGEYECKVRNSDGELQTAKAFLN 241
            ||.....|.|.|.|:::..:  .|:....|.|...:|.        .|:|.|..|....: ..:|
  Rat   282 PEILGYRWAKGGFLIEDAHE--SRYETNVDYSFFTEPV--------SCEVYNKVGSTNVS-TLVN 335

  Fly   242 IQYKAKVIYAPPEVFLPYGQPAVLDCHFRANPPLKNLRWEKDGLLFDSY---NVPGVFYKMN--- 300
            :.:..:::..|.......|....|.|.:..|||| .|.|.|.    ||.   .:||...:.|   
  Rat   336 VH
FAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPL-TLTWTKK----DSNMGPRLPGSPPEANLSA 395

  Fly   301 ------GSLFFAKVDENHAGSYTCTPYNDLGTDGPSPVISV-------IVLRPPIFSVTPKAIYI 352
                  ..|....|.:..||:|||...        .|.|.|       .|..|||  ::.:|:..
  Rat   396 QVLSNSNQLLLKSVTQADAGTYTCRAI--------VPRIGVAEREVPLYV
NGPPI--ISSEAVQF 450

  Fly   353 QKLGEAAELPCEAIDRDGNNRP--SIIWGRKDG-------QPLPADRFSLSGG---NLTITGLVE 405
            ...|:..::.|..    |:..|  .|.|..|:.       :....:|.:...|   .|||..::|
  Rat   451 AVRGDGGKVECFI----GSTPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVME 511

  Fly   406 GD-RGIYECSATNEAATITAEAELMIENIAPRAPYNLTANSTETCITIRWQPGYLR----PNLEY 465
            .| :..|.|:|.|.....||..:|....:   .|..:.|.:|...       |.|.    ..|.:
  Rat   512 ADFQTHYNCTAWNSFGPGTAIIQLE
EREV---LPVGIIAGATIGA-------GILLVFSFAALVF 566

  Fly   466 TVWYRLMEAPEWRTLRVLDKKV----MEATVQH-------------------------------- 494
            .::.|...:.:..|||.||.||    .|....|                                
  Rat   567 FLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTTSISTATRVMKAIYSSFKDDVDLKQ 631

  Fly   495 ------LQPGKEYEFMVLSQDKYG-----DGMFSKQFRF--QTLPSPIRADDFDAQQLQHDLGQV 546
                  ::..:|||....:...|.     |...|:...:  ...|.|.|.|...:.:|.|..|..
  Rat   632 DLHCDTIETREEYEMKDPTNGYYNVRAHEDRPSSRAVLYADYRAPGPTRFDGRPSSRLSHSSGYA 696

  Fly   547 ------TAPAGGLG---------APWNLTAISNQQGWLLHWE-------HPVQGLEGLRLYAVRW 589
                  .|||...|         ||......|.     |.:|       ||..|..|...|.:.:
  Rat   697 QLNTYSRAPASDYGTEPTPSGPSAPGGTDTTSQ-----LSYENYEKFNSHPFPGAAGYPTYRLGY 756

  Fly   590 WKEPEHFLIGHAETFDNYYQLRHLKEDTLFKV--QVLAVGTETQQSVPSH 637
            .:.|...|  ....::.|..:......|.|..  |....|...||.:.:|
  Rat   757 PQAPPSGL--ERTPYEAYDPIGKYATATRFSYTSQHSDYGQRFQQRMQTH 804

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bdlNP_608822.1 IG_like 42..128 CDD:214653 15/79 (19%)
Ig 43..131 CDD:299845 15/82 (18%)
I-set 153..242 CDD:254352 20/89 (22%)
Ig 157..242 CDD:299845 20/85 (24%)
Ig_2 252..337 CDD:290606 26/103 (25%)
IG_like 260..327 CDD:214653 22/78 (28%)
I-set 341..428 CDD:254352 23/99 (23%)
IGc2 356..419 CDD:197706 18/75 (24%)
FN3 435..524 CDD:238020 22/141 (16%)
FN3 554..636 CDD:238020 20/99 (20%)
Kirrel1XP_006232737.1 I-set 54..148 CDD:254352
Ig 57..148 CDD:299845
Ig2_KIRREL3-like 170..251 CDD:143236 19/98 (19%)
I-set 255..336 CDD:254352 20/91 (22%)
Ig_2 259..337 CDD:290606 21/88 (24%)
Ig_2 340..437 CDD:290606 26/109 (24%)
IG_like 346..437 CDD:214653 26/103 (25%)
Ig5_KIRREL3 439..536 CDD:143306 24/102 (24%)
IG_like 451..536 CDD:214653 20/88 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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