DRSC/TRiP Functional Genomics Resources

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Protein Alignment bdl and Ncam2

DIOPT Version :9

Sequence 1:NP_608822.1 Gene:bdl / 33635 FlyBaseID:FBgn0028482 Length:719 Species:Drosophila melanogaster
Sequence 2:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus


Alignment Length:720 Identity:161/720 - (22%)
Similarity:263/720 - (36%) Gaps:153/720 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 EAKVGSHVVFNCYIDFPFDAPIPYLVHWTKDNKKIFTWYEQETSTSELFNGRLHLVENHPEFGRA 108
            |.|.|......|.:.   .:|.| .|.|...|:::.|          :.:.|..::.|:      
  Rat   125 EFKQGEDAEVVCRVS---SSPAP-AVSWLYHNEEVTT----------IPDNRFAVLANN------ 169

  Fly   109 SVNLTAIRESDQGWYHCQVSFPNRSP-SVRNNGTAYHLAVQGGSLIRIPPV--------NQTIRE 164
            ::.:..|.:||:|.|.|:.....|.. ..|:      :.|    ::.:||.        |.|...
  Rat   170 NLQILNINKSDEGIYRCEGRVEARGEIDFRD------IIV----IVNVPPAIVMPQKSFNATAER 224

  Fly   165 GQTAFFHCVMKHPENSQASWYKDGVLLQEVQDLVRRFYMGPDGSLSIDPTMMSDLGEYECKVRNS 229
            |:.....|......:...||:::|.|::|.:..:.:   |.:..|::...:..|.|.|.||..|.
  Rat   225 GEEMTLTCKASGSPDPAISWFRNGKLIEENEKYILK---GSNTELTVRNIINKDGGSYVCKATNK 286

  Fly   230 DGELQTAKAFLNIQYKAKVIYAPPEVFLPYGQPAVLDCHFRANPPLKNLRWEK--DGLLF-DSYN 291
            .||.| .:|||.:..:..::....|.....|. ..|.|..... |:..:.|::  ||:.| :...
  Rat   287 AGEDQ-KQAFLQVFVQPHILQLKNETTSENGH-VTLICEAEGE-PVPEITWKRAIDGVTFSEGDK 348

  Fly   292 VPGVFYKMNG-----SLFFAKVDENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPKAIY 351
            .|....::.|     ||....|..:.:|.|.|...:.:|  |....:.:.:...|.| |:.:.:|
  Rat   349 SPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIG--GHQRSMHLDIEYAPKF-VSNQTMY 410

  Fly   352 IQKLGEAAELPCEAIDRDGNNRPSIIWGRKDGQPLPADRF----SLSGGN---LTITGLVEGDRG 409
            ....|....:.|   |...|...||.| |::...|||...    :.|.|.   |.|....:.|.|
  Rat   411 YSWEGNPINISC---DVKANPPASIHW-RREKLVLPAKNTTHLKTHSVGRKMILEIAPTSDNDFG 471

  Fly   410 IYECSATNEAATITAEAELMIENI--APRAPYNLTANSTETCITIRWQP---GYLRPNLEYTVWY 469
            .|.|:|||...|...|..|.:.::  :||....:..:.|...|:.. :|   |.: |...|.|..
  Rat   472 RYNCTATNRIGTRFQEYILELADVPSSPRGVKIIELSQTTAKISFN-KPESHGGV-PIHHYQVDV 534

  Fly   470 RLMEAPEWRTLRVLDKKVMEATV--QHLQPGKEYEFMVLSQDKYGDGMFSKQFRFQTLP------ 526
            :.:.:..|:.:|   ...::.||  ..|:|...||..|.:.:..|.|.:||...|||||      
  Rat   535 KEVTSETWKIVR---SHGVQTTVVLSSLEPNTTYEVRVAAVNGKGQGDYSKIEIFQTLPVREPSP 596

  Fly   527 -----SPIRADDFDAQQLQHDLGQVTAPAGGLGAP-----WNLTAISNQQGWLLHWEHPVQGLEG 581
                 .|.....|.....:.|.|         |||     ....:...:..||   |..|||   
  Rat   597 PSIHGQPSSGKSFKISITKQDDG---------GAPILEYIVKYRSKDKEDQWL---EKKVQG--- 646

  Fly   582 LRLYAVRWWKEPEHFLIGHAETFDNYYQLRHLKEDTLFKVQVLAVG-------TETQQSVPSHEL 639
                      ..:|.:            |.||:....::||:.|..       |..:.|:|....
  Rat   647 ----------NKDHII------------LEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPPKPN 689

  Fly   640 LI-DVPSQRKVRALIIGSSVGVIFLLCAL----CAFLYVKRSC------LRHLFAKDSSASEDED 693
            :| |..........|||..|..:.|:..:    |.|:   |.|      .|.:..|.|.:|....
  Rat   690 IIKDTLFNGLGLGAIIGLGVAALLLILVVTDVSCFFI---RQCGLLMCITRRMCGKKSGSSGKSK 751

  Fly   694 TAESG 698
            ..|.|
  Rat   752 ELEEG 756

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bdlNP_608822.1 IG_like 42..128 CDD:214653 18/83 (22%)
Ig 43..131 CDD:299845 18/86 (21%)
I-set 153..242 CDD:254352 25/96 (26%)
Ig 157..242 CDD:299845 24/92 (26%)
Ig_2 252..337 CDD:290606 19/92 (21%)
IG_like 260..327 CDD:214653 17/74 (23%)
I-set 341..428 CDD:254352 28/93 (30%)
IGc2 356..419 CDD:197706 22/69 (32%)
FN3 435..524 CDD:238020 23/93 (25%)
FN3 554..636 CDD:238020 18/93 (19%)
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452
Ig strand B 38..42 CDD:409452
Ig strand C 50..54 CDD:409452
Ig strand E 76..80 CDD:409452
Ig strand F 90..95 CDD:409452
Ig strand G 104..107 CDD:409452
IGc2 128..189 CDD:197706 16/80 (20%)
Ig strand B 130..139 CDD:409353 1/8 (13%)
Ig strand C 145..153 CDD:409353 2/7 (29%)
Ig strand C' 156..159 CDD:409353 1/12 (8%)
Ig strand D 162..167 CDD:409353 1/4 (25%)
Ig strand E 168..175 CDD:409353 1/12 (8%)
IgI_1_MuSK 209..298 CDD:409562 24/92 (26%)
Ig strand B 228..232 CDD:409562 0/3 (0%)
Ig strand C 241..245 CDD:409562 1/3 (33%)
Ig strand E 264..268 CDD:409562 1/3 (33%)
Ig strand F 278..283 CDD:409562 2/4 (50%)
Ig strand G 291..294 CDD:409562 1/3 (33%)
Ig 300..397 CDD:416386 19/100 (19%)
Ig strand A 300..305 CDD:409353 0/4 (0%)
Ig strand A' 309..313 CDD:409353 1/3 (33%)
Ig strand B 317..325 CDD:409353 2/8 (25%)
Ig strand C 331..337 CDD:409353 1/5 (20%)
Ig strand C' 340..343 CDD:409353 1/2 (50%)
Ig strand D 353..359 CDD:409353 0/5 (0%)
Ig strand E 362..368 CDD:409353 2/5 (40%)
Ig strand F 376..384 CDD:409353 3/7 (43%)
Ig strand G 387..397 CDD:409353 2/11 (18%)
Ig_3 401..479 CDD:404760 24/82 (29%)
Ig strand B 418..422 CDD:409353 0/3 (0%)
Ig strand C 431..435 CDD:409353 3/4 (75%)
Ig strand E 458..462 CDD:409353 1/3 (33%)
Ig strand F 472..477 CDD:409353 2/4 (50%)
Ig strand G 486..489 CDD:409353 1/2 (50%)
FN3 496..588 CDD:238020 23/96 (24%)
fn3 594..678 CDD:394996 20/120 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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