DRSC/TRiP Functional Genomics Resources

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Protein Alignment bdl and LRIT1

DIOPT Version :9

Sequence 1:NP_608822.1 Gene:bdl / 33635 FlyBaseID:FBgn0028482 Length:719 Species:Drosophila melanogaster
Sequence 2:NP_056428.1 Gene:LRIT1 / 26103 HGNCID:23404 Length:623 Species:Homo sapiens


Alignment Length:273 Identity:57/273 - (20%)
Similarity:97/273 - (35%) Gaps:63/273 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   260 GQPAVLDCHFRANPPLKNLRWEK------DGLLFDSYNVPGVFYKMNGSLFFAKVDENHAGSYTC 318
            |..|:|.|. ....|...:.|.:      :|.:....:..|..:.:.|....:.:|   :|.|.|
Human   268 GGTALLRCG-ATGVPGPEMSWRRANGRPLNGTVHQEVSSDGTSWTLLGLPAVSHLD---SGDYIC 328

  Fly   319 TPYNDLGTDGPSPVISVIVLRPPI---FSVTPKAIYIQK--LGEAA------------ELPCEAI 366
            ...|.||..  ..|||:||..||.   .|.:|.|::.:.  .||||            ::|..|:
Human   329 QAKNFLGAS--ETVISLIV
TEPPTSTEHSGSPGALWARTGGGGEAAAYNNKLVARHVPQIPKPAV 391

  Fly   367 DRDGNNRPSIIWGRKDGQPLPADRFSLSG-GNLTITGLVEGDRGIYECSATNEAATITAEAELMI 430
            ...|.:.||      ..:.|..:.|.:.. |.|:     :|..|             .:||. |:
Human   392 LATGPSVPS------TKEELTLEHFQMDALGELS-----DGRAG-------------PSEAR-MV 431

  Fly   431 ENIAPRAPYNLTANSTETCITIRWQPGYLRPNLEYTVWYRLMEAPEWRTLRVLDKKVMEATVQHL 495
            .::.       ....|...:::.|:....:....::|.|.:......|.:.|...|. ..|:..|
Human   432 RSVK-------VVGDTYHSVSLVWKAPQAKNTTAFSVLYAVFGQHSMRRVIVQPGKT-RVTITGL 488

  Fly   496 QPGKEYEFMVLSQ 508
            .|..:|...|..|
Human   489 LPKTKYVACVCVQ 501

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bdlNP_608822.1 IG_like 42..128 CDD:214653
Ig 43..131 CDD:299845
I-set 153..242 CDD:254352
Ig 157..242 CDD:299845
Ig_2 252..337 CDD:290606 19/82 (23%)
IG_like 260..327 CDD:214653 16/72 (22%)
I-set 341..428 CDD:254352 21/104 (20%)
IGc2 356..419 CDD:197706 15/75 (20%)
FN3 435..524 CDD:238020 13/74 (18%)
FN3 554..636 CDD:238020
LRIT1NP_056428.1 LRR 1 60..81
leucine-rich repeat 61..84 CDD:275378
LRR_8 63..143 CDD:290566
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..202 CDD:290566
LRR_4 131..171 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>240 CDD:301599
Ig 267..345 CDD:299845 19/82 (23%)
IG_like 267..345 CDD:214653 19/82 (23%)
FN3 431..498 CDD:214495 11/74 (15%)
LRR 6. /evidence=ECO:0000305 571..594
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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