DRSC/TRiP Functional Genomics Resources

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Protein Alignment bdl and Kirrel2

DIOPT Version :9

Sequence 1:NP_608822.1 Gene:bdl / 33635 FlyBaseID:FBgn0028482 Length:719 Species:Drosophila melanogaster
Sequence 2:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus


Alignment Length:654 Identity:134/654 - (20%)
Similarity:219/654 - (33%) Gaps:158/654 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    68 LVHWTKDNKKIFTWYEQETSTSELFNGRLHLVENHPEFGRASVNLTAIRESDQGWYHCQVSFPNR 132
            ||.||||...:       ....:|.....:.:..:...|:..:::..:...|:..|.||.|    
Mouse    50 LVQWTKDGLAL-------GGERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQAS---- 103

  Fly   133 SPSVRNNGTAYHLAVQ-------GG---SLIRIPPVNQTIR---EGQTAFFHCVMKHPENSQASW 184
            ...:|:.....|:.|.       ||   ||:...|.|.|.|   :.:.|        ||   ..|
Mouse   104 QAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDSRPA--------PE---LLW 157

  Fly   185 YKDGVLLQEV---QDLVRRFYMGP-DGSLSIDPTMMSDLGEYECKVRNSDGELQTAK---AFLNI 242
            ::||:.|...   |..::....|. :.:|.:.|:...|.....|:.|:.  .|.|.:   ..|::
Mouse   158 FRDGIRLDGSSFHQTTLKDKATGTVENTLFLTPSSHDDGATLICRARSQ--ALPTGRDTAVTLSL 220

  Fly   243 QYKAKVIYAPPEVFLPYGQPAVLDCHFRANPPLKNLRWEKDGLLFDSYNVPGVFYKMNGSLFFAK 307
            ||...|..:.....:..|:.....|...|.||:...||.|.|........|.:....:.:.....
Mouse   221 QYPPMVTLSAEPQTVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADATFLTEP 285

  Fly   308 VDENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPKAIYIQKLGEAAELPCEAIDRDGNN 372
            |        :|...|.:|:...|..:.  ||..||....||::.:. :|:.|...|  :.| ||.
Mouse   286 V--------SCEVSNAVGSANRSTALE--VLYGPILQAKPKSVSVD-VGKDASFSC--VWR-GNP 336

  Fly   373 RPSIIWGRKDGQPLPADRFSLSGGNLTITGLVEGDRGIYECSAT---------NEAATITAEAEL 428
            .|.|.|.|..|..:.:     ||..|.:..:...|.|.|.|.|.         ...|.:|..|..
Mouse   337 LPRITWTRMGGSQVLS-----SGPTLRLPSVALEDAGDYVCRAEPRRTGLGGGKAQARLTVNAPP 396

  Fly   429 MIENIAP-----RAPYNLT----ANSTETCITIRWQPGYLRPNLEYTVWYRLMEAPEWRTLRVLD 484
            ::..:.|     |.|..|.    |:.....:...|..|:|..............|||        
Mouse   397 VVTALQPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPE-------- 453

  Fly   485 KKVMEA-------TVQHLQPGKEYEFMV----LSQDKYGDGMFSKQF-RFQTLPS-PIRADDFDA 536
               :|.       :|.|:...:|.:|..    .::::.|:|...... |...||: .|.|....|
Mouse   454 ---VEGGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRRDLLPTVRIVAGAASA 515

  Fly   537 Q------------------QLQHDLGQVTAPAGGLGA----PWNLTAISNQQGWLLHWEHP---V 576
            .                  .|......|..|....|:    |...|..|..:|.::|.:|.   :
Mouse   516 ATSLLMVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSSRGPEEETGSSEDRGPIVHTDHSDLVL 580

  Fly   577 QGLEGLRLYAVRWWKEPEHFLIGHAETFDNYYQLRHLKEDTLFKVQVLAVGTETQQSVPSHELLI 641
            :..|.|..      |:|.          :.||::|.:...       |::|     ..|...|.:
Mouse   581 EEKEALET------KDPT----------NGYYRVRGVSVS-------LSLG-----EAPGGGLFL 617

  Fly   642 DVPS 645
            ..||
Mouse   618 PPPS 621

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bdlNP_608822.1 IG_like 42..128 CDD:214653 12/59 (20%)
Ig 43..131 CDD:299845 13/62 (21%)
I-set 153..242 CDD:254352 21/98 (21%)
Ig 157..242 CDD:299845 21/94 (22%)
Ig_2 252..337 CDD:290606 15/84 (18%)
IG_like 260..327 CDD:214653 14/66 (21%)
I-set 341..428 CDD:254352 26/95 (27%)
IGc2 356..419 CDD:197706 19/71 (27%)
FN3 435..524 CDD:238020 19/109 (17%)
FN3 554..636 CDD:238020 16/88 (18%)
Kirrel2NP_766486.1 IG 27..116 CDD:214652 14/76 (18%)
Ig 122..220 CDD:416386 25/110 (23%)
Ig strand A 123..126 CDD:409353 0/2 (0%)
Ig strand A' 129..133 CDD:409353 0/3 (0%)
Ig strand B 140..147 CDD:409353 3/6 (50%)
Cell attachment site. /evidence=ECO:0000255 146..148 0/1 (0%)
Ig strand C 153..158 CDD:409353 2/7 (29%)
Ig strand C' 161..163 CDD:409353 1/1 (100%)
Ig strand D 166..173 CDD:409353 1/6 (17%)
Ig strand E 180..188 CDD:409353 2/7 (29%)
Ig strand F 197..205 CDD:409353 1/7 (14%)
Ig strand G 211..217 CDD:409353 0/5 (0%)
Ig_3 223..292 CDD:404760 13/76 (17%)
Ig strand B 241..245 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 1/3 (33%)
Ig strand E 272..275 CDD:409353 0/2 (0%)
Ig strand F 281..290 CDD:409353 2/16 (13%)
Ig strand G 298..301 CDD:409353 0/2 (0%)
Ig 315..392 CDD:416386 22/85 (26%)
Ig strand A' 316..321 CDD:409353 1/4 (25%)
Ig strand B 324..333 CDD:409353 2/10 (20%)
Ig strand C 339..343 CDD:409353 1/3 (33%)
Ig strand C' 346..348 CDD:409353 0/1 (0%)
Ig strand D 351..354 CDD:409353 0/7 (0%)
Ig strand E 355..360 CDD:409353 1/4 (25%)
Ig strand F 368..376 CDD:409353 4/7 (57%)
Ig strand G 382..392 CDD:409353 1/9 (11%)
Ig 394..498 CDD:416386 19/114 (17%)
Ig strand A 395..399 CDD:409353 0/3 (0%)
Ig strand A' 401..404 CDD:409353 0/2 (0%)
Ig strand B 412..419 CDD:409353 1/6 (17%)
Ig strand C 426..431 CDD:409353 0/4 (0%)
Ig strand C' 433..436 CDD:409353 1/2 (50%)
Ig strand D 444..451 CDD:409353 0/6 (0%)
Ig strand E 461..468 CDD:409353 1/6 (17%)
Ig strand F 479..486 CDD:409353 0/6 (0%)
Ig strand G 489..496 CDD:409353 2/6 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576 8/33 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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