DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bdl and FCGR3A

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001121064.2	Gene:	FCGR3A / 2214	HGNCID:	3619	Length:	358	Species:	Homo sapiens

Alignment Length:	191	Identity:	41/191 - (21%)
Similarity:	68/191 - (35%)	Gaps:	40/191 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 TAYHLAVQGG-------SLIRIPPVNQTIREGQTAFFHCVMKH-PENSQASWYKDGVLLQEVQDL 197
            ||..|.|..|       :::.:.|....:.|..:....|...: ||::...|:.:..|:.
Human   113 TALLLLVSAGMRTDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLIS----- 172

  Fly   198 VRRFYMGPDGSLSIDPTMMSDLGEYECKVR----NSDGELQTAKAFLNIQYKAKVIYAPPEVFLP 258
                  ....|..||...:.|.|||.|:..    :...:|:....:|.:|       ||..|| .
Human   173 ------SQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQ-------APRWVF-K 223

  Fly   259 YGQPAVLDCHFRANPPLKNLRWEKDGLLFDSYNVPG-VFYKMNGSLFFAKVDENHAGSYTC 318
            ...|..|.||...|..|..:.:.::|        .| .::..|...:..|.....:|||.|
Human   224 EEDPIHLRCHSWKNTALHKVTYLQNG--------KGRKYFHHNSDFYIPKATLKDSGSYFC 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653
		Ig	43..131	CDD:299845
		I-set	153..242	CDD:254352	17/93 (18%)
		Ig	157..242	CDD:299845	17/89 (19%)
		Ig_2	252..337	CDD:290606	17/68 (25%)
		IG_like	260..327	CDD:214653	14/60 (23%)
		I-set	341..428	CDD:254352
		IGc2	356..419	CDD:197706
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
FCGR3A	NP_001121064.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910