DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdl and FCGR2B

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	XP_024309811.1	Gene:	FCGR2B / 2213	HGNCID:	3618	Length:	324	Species:	Homo sapiens

Alignment Length:	246	Identity:	56/246 - (22%)
Similarity:	88/246 - (35%)	Gaps:	57/246 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 GSLSIDPTMMSDLGEYECKVRNSDGELQTAKAFLNIQYKAKVIYAPPEVFLPYGQP--------- 262
            |.||..|.:.::....:||.....|.:....|.|.:...|....|||:..|.. :|
Human     2 GILSFLPVLATESDWADCKSPQPWGHMLLWTAVLFLAPVAGTPAAPPKAVLKL-EPQWINVLQED 65

  Fly   263 -AVLDCHFRANPPLKNLRWEKDGLLFDSYNVPGVFYKMNGSLFFAKVDENHAGSYTCTPYNDLGT 326
             ..|.|....:|...:::|..:|.|..::..|...:|.|         .|.:|.|||    ..|.
Human    66 SVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPSYRFKAN---------NNDSGEYTC----QTGQ 117

  Fly   327 DGPSPVISVIVLRPPIFSVTPKAIYIQKLGEAAELPCEAIDRDGNNRPSIIWGRKDGQPL----- 386
            ...|..:.:.||...:...||...:.:  ||...|.|.:            |  || :||
Human   118 TSLSDPVHLTVLSEWLVLQTPHLEFQE--GETIVLRCHS------------W--KD-KPLVKVTF 165

  Fly   387 ----PADRFSLSGGNLTITGLVEGDRGIYECSA-------TNEAATITAEA 426
                .:.:||.|..|.:|........|.|.|:.       :::..|||.:|
Human   166 FQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQA 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653
		Ig	43..131	CDD:299845
		I-set	153..242	CDD:254352	9/34 (26%)
		Ig	157..242	CDD:299845	9/34 (26%)
		Ig_2	252..337	CDD:290606	20/94 (21%)
		IG_like	260..327	CDD:214653	16/76 (21%)
		I-set	341..428	CDD:254352	23/102 (23%)
		IGc2	356..419	CDD:197706	17/78 (22%)
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
FCGR2B	XP_024309811.1	Ig1_FcgammaR_like	50..128	CDD:143229	18/91 (20%)
FCGR2B	XP_024309811.1	Ig2_FcgammaR_like	132..214	CDD:319307	21/98 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910