| Sequence 1: | NP_608822.1 | Gene: | bdl / 33635 | FlyBaseID: | FBgn0028482 | Length: | 719 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_005206.2 | Gene: | DCC / 1630 | HGNCID: | 2701 | Length: | 1447 | Species: | Homo sapiens |
| Alignment Length: | 697 | Identity: | 160/697 - (22%) |
|---|---|---|---|
| Similarity: | 260/697 - (37%) | Gaps: | 134/697 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 13 GSALLALLAIILLMNISCTSAARDHRRQTNLEAKVGSHVVFNCYIDFPFDAPIPYLVHWTKDNKK 77
Fly 78 IFTWYEQETSTSELFNGRLHLVEN--HPEFGRASVNLTAIRESDQGWYHCQVSFPNRSPSVRNNG 140
Fly 141 TAYHLAVQGGSLIRIPPVNQTIREGQTAFFHCVMKHPENSQASWYKDGVLLQEVQDLV-----RR 200
Fly 201 FYMGPDGSLSIDPTMMSDLGEYECKVRN---------------SDGELQTAKAFLNIQYKAKVIY 250
Fly 251 APPEVFLPYGQPAVLDCHFRANPPLKNLRW----EKDGLLFDSYNVPGVFYKMNGSLFFAKVDEN 311
Fly 312 HAGSYTC-TPYNDLGTDGPSPVISVIVLRPPIFSVTPKAIYIQKLGEAAELPCEAIDRDGNNRPS 375
Fly 376 IIWGRKDGQPLPADRFSLSGG-NLTITGLVEGDRGIYECSATNEAATITAEAELMI-------EN 432
Fly 433 IAPRAPYNLT-ANSTETCITIRWQ-PGYLRPNLE-YTVWYRLMEAPEWRTLRVLDKKVMEATVQH 494
Fly 495 LQPGKEYEFMVLSQDKYGDGMFSKQFRFQTLPSPIRADDFDAQQLQHDLGQVTAPAGGLGAPWNL 559
Fly 560 TAIS-NQQGWLLHWEHPVQG---LEGLRLYA--VRWWKEPEHFLIGHAETFDNYYQLRHLKEDTL 618
Fly 619 FKVQVLAV-----GTETQQ----------SVPSHELLIDVPSQRKVR 650 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| bdl | NP_608822.1 | IG_like | 42..128 | CDD:214653 | 19/87 (22%) |
| Ig strand C | 69..72 | CDD:409512 | 0/2 (0%) | ||
| Ig strand E | 108..112 | CDD:409512 | 0/3 (0%) | ||
| Ig strand F | 122..127 | CDD:409512 | 2/4 (50%) | ||
| Ig | 153..242 | CDD:472250 | 25/108 (23%) | ||
| Ig strand B | 168..172 | CDD:409544 | 0/3 (0%) | ||
| Ig strand C | 181..185 | CDD:409544 | 0/3 (0%) | ||
| Ig strand E | 207..211 | CDD:409544 | 2/3 (67%) | ||
| Ig strand F | 221..226 | CDD:409544 | 2/4 (50%) | ||
| Ig strand G | 235..238 | CDD:409544 | 0/2 (0%) | ||
| Ig_3 | 247..322 | CDD:464046 | 20/79 (25%) | ||
| Ig | 341..428 | CDD:472250 | 28/87 (32%) | ||
| Ig strand B | 359..363 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 375..380 | CDD:409353 | 1/4 (25%) | ||
| Ig strand E | 396..400 | CDD:409353 | 3/4 (75%) | ||
| Ig strand F | 410..415 | CDD:409353 | 2/4 (50%) | ||
| Ig strand G | 423..426 | CDD:409353 | 0/2 (0%) | ||
| FN3 | 435..524 | CDD:238020 | 20/91 (22%) | ||
| FN3 | 554..636 | CDD:238020 | 25/102 (25%) | ||
| DCC | NP_005206.2 | IgI_1_Neogenin_like | 39..136 | CDD:409387 | 22/115 (19%) |
| Ig strand A | 39..42 | CDD:409387 | 1/2 (50%) | ||
| Ig strand A' | 45..51 | CDD:409387 | 0/5 (0%) | ||
| Ig strand B | 55..65 | CDD:409387 | 2/9 (22%) | ||
| Ig strand C | 70..76 | CDD:409387 | 2/8 (25%) | ||
| Ig strand C' | 78..81 | CDD:409387 | 1/4 (25%) | ||
| Ig strand D | 88..93 | CDD:409387 | 0/4 (0%) | ||
| Ig strand E | 95..101 | CDD:409387 | 3/6 (50%) | ||
| Ig strand F | 113..120 | CDD:409387 | 3/6 (50%) | ||
| Ig strand G | 125..136 | CDD:409387 | 0/13 (0%) | ||
| Ig_3 | 139..216 | CDD:464046 | 18/82 (22%) | ||
| I-set | 241..327 | CDD:400151 | 24/103 (23%) | ||
| Ig strand B | 257..261 | CDD:409562 | 3/3 (100%) | ||
| Ig strand C | 270..274 | CDD:409562 | 0/3 (0%) | ||
| Ig strand E | 293..297 | CDD:409562 | 1/3 (33%) | ||
| Ig strand F | 307..312 | CDD:409562 | 3/4 (75%) | ||
| Ig strand G | 322..325 | CDD:409562 | 0/2 (0%) | ||
| Ig | 334..417 | CDD:472250 | 27/86 (31%) | ||
| Ig strand B | 348..352 | CDD:409388 | 1/3 (33%) | ||
| Ig strand C | 361..365 | CDD:409388 | 0/3 (0%) | ||
| Ig strand E | 383..387 | CDD:409388 | 2/3 (67%) | ||
| Ig strand F | 397..402 | CDD:409388 | 2/4 (50%) | ||
| Ig strand G | 410..413 | CDD:409388 | 0/2 (0%) | ||
| FN3 | 429..521 | CDD:238020 | 20/91 (22%) | ||
| FN3 | <478..901 | CDD:442628 | 43/191 (23%) | ||
| FN3 | 946..1041 | CDD:238020 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1126..1152 | ||||
| Neogenin_C | 1148..1445 | CDD:461954 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1165..1222 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1288..1330 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1394..1419 | ||||
| Interaction with MYO10. /evidence=ECO:0000269|PubMed:21642953 | 1432..1439 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||