DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdl and FCRLB

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001002901.1	Gene:	FCRLB / 127943	HGNCID:	26431	Length:	426	Species:	Homo sapiens

Alignment Length:	322	Identity:	77/322 - (23%)
Similarity:	118/322 - (36%)	Gaps:	97/322 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 LIRIPPVNQTIREGQTAFFHCVMKHPENSQASWYKDGVLLQEVQDLVRRFYMG----PDGSLSID 212
            ::.:.|...||.:|:.....|...||            ||.|:|.:...:|:|    |....||:
Human    24 ILSLHPPWTTIFKGERVTLKCDGYHP------------LLLELQPISTLWYLGHLLLPSHKKSIE 76

  Fly   213 PTMMSDLGEYECKVRN---SDG-ELQTAKAFLNIQYKAKVIYAPPEVFLPYGQPAVLDCHFRANP 273
               :...|.|.|:.|.   ||. .|..:..:|.:|    |.|||  ||  .|:|.||.|....:.
Human    77 ---VQTPGVYRCQTRGAPVSDPIHLSVSNDWLILQ----VPYAP--VF--EGEPLVLRCRGWYDK 130

  Fly   274 PLKNLRWEKDGLLFDSYNVPGVFY---KMNGSLFFAKVDENHAGSYTCTPYNDLGTDGPSPVISV 335
            .:..|.:..||        ..|.|   ..|.::..|:..:  :|.|.|:     ||      :.:
Human   131 VVYKLHYYHDG--------QAVRYFHSSANYTVLQARASD--SGRYQCS-----GT------MRI 174

  Fly   336 IVLRPPIFSVTPKAIYIQKLGEAAEL----PCEAIDRDGNNRPSIIWG-----------RKDGQP 385
            .|...|:|| ...|:.:|:|..|..|    |.||       |.:.:.|           :|...|
Human   175 PVESAPMFS-AKVAVTVQELFRAPVLRVMGPREA-------RGAALGGVVLRCDTRLHPQKRDTP 231

  Fly   386 LPADRFSLS--------GGNLTITGLVEGDRGIYECSATNEAATITAEAELMIENIAPRAPY 439
            |....:..|        |...|:......:...|.|    ||||.|       .::..|:|:
Human   232 LQFAFYKYSRAVRRFDWGAEYTVPEPEVEELESYWC----EAATAT-------RSVRKRSPW 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653
		Ig	43..131	CDD:299845
		I-set	153..242	CDD:254352	24/96 (25%)
		Ig	157..242	CDD:299845	24/92 (26%)
		Ig_2	252..337	CDD:290606	20/87 (23%)
		IG_like	260..327	CDD:214653	16/69 (23%)
		I-set	341..428	CDD:254352	26/109 (24%)
		IGc2	356..419	CDD:197706	15/85 (18%)
		FN3	435..524	CDD:238020	2/5 (40%)
		FN3	554..636	CDD:238020
FCRLB	NP_001002901.1	Ig1_FcgammaR_like	23..100	CDD:143229	23/90 (26%)
		Ig2_FcgammaR_like	104..186	CDD:143230	29/111 (26%)
		IG_like	114..190	CDD:214653	24/99 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	400..426
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910