DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bdl and iglon5

DIOPT Version :9

Sequence 1:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	344	Identity:	78/344 - (22%)
Similarity:	128/344 - (37%)	Gaps:	71/344 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LALLAIILL---MNISCTSAARDHRRQTNLEAKVGSHVVFNCYIDFPFDAPIPYLVHWTKDNKKI 78
            ||.|.|::|   :.:.||.....   ..|.....|.:...:|.||.....     |.|...:..:
Frog    10 LASLGIVMLAQVLFVQCTEFVPP---ADNYTVSQGDNATLSCLIDDKVTR-----VAWLNRSNIL 66

  Fly    79 FTWYEQETSTSELFNGRLHLVEN-HPEFGRASVNLTAIRESDQGWYHCQVSFPNRSPSVRNNGTA 142
            :...::.:     .:.|:.|:.| ..|:   |:.:|.:..:|:|.|.|  ||....   :.:.:.
Frog    67 YAGKDKWS-----IDSRVQLLTNTKSEY---SIVITHVDVADEGLYTC--SFQTED---KPHTSQ 118

  Fly   143 YHLAVQGGSLIRIPPVNQTIREGQTAFFHCVMKHPENSQASWYK-------DGVLLQEVQDLVRR 200
            .:|.||..:.|.....:.|:.||......|:.........:|.:       :|.|| |:.::.|:
Frog   119 VYLIVQVPAKIVNISSSVTVNEGSNVNLQCLAVGKPEPTITWQQLSEGFSSEGELL-EITEINRQ 182

  Fly   201 FYMGPDGSLSIDPTMMSDLGEYECKVRNSDGELQTAKAFLNIQYKAKVIYAPPEVF------LPY 259
                             ..|:|||...|......|.|..:.:.|       ||.:.      .|.
Frog   183 -----------------QAGDYECVTSNGVSVPDTKKVQITVNY-------PPYITDVKNAQSPV 223

  Fly   260 GQPAVLDCHFRANPPLKNLRWEKDGLLFDSYNVPGVFYKMNGS---LFFAKVDENHAGSYTCTPY 321
            |:||.|.|...|.||.: ..|.||..........|:..|...|   :.|:.|...|.|:|||...
Frog   224 GRPATLRCKAMAVPPAE-FEWYKDEKRRLISGTEGLSIKTESSWSVIVFSNVTSRHYGNYTCLAS 287

  Fly   322 NDLGTDGPSPVISVIVLRP 340
            |.||:...    |:.:|:|
Frog   288 NKLGSFNS----SLRLLKP 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdl	NP_608822.1	IG_like	42..128	CDD:214653	17/86 (20%)
		Ig	43..131	CDD:299845	18/88 (20%)
		I-set	153..242	CDD:254352	18/95 (19%)
		Ig	157..242	CDD:299845	17/91 (19%)
		Ig_2	252..337	CDD:290606	28/93 (30%)
		IG_like	260..327	CDD:214653	24/69 (35%)
		I-set	341..428	CDD:254352	78/344 (23%)
		IGc2	356..419	CDD:197706
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	20/112 (18%)
		IG_like	35..123	CDD:214653	20/105 (19%)
		Ig	126..207	CDD:299845	18/98 (18%)
		I-set	128..207	CDD:254352	18/96 (19%)
		I-set	210..299	CDD:254352	28/93 (30%)
		Ig	227..298	CDD:143165	23/75 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910